Discuss This Drug

Spironolactone

CHEBI:CHEBI_9241

Definition

A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Chemical Information

Molecular Formula
C24H32O4S
Molecular Mass
416.57448
Charge
0
SMILES
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]33CCC(=O)O3)[C@]1([H])[C@@H](CC1=CC(=O)CC[C@]21C)SC(C)=O
InChI
InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
InChIKey
LXMSZDCAJNLERA-ZHYRCANASA-N

Alternative Names

  • 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
  • espironolactona
  • spironolactone
  • Spironolactone
  • spironolactonum
  • spironolattone

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
9997
oboInOwl#hasDbXref
Wikipedia:Spironolactone
core#notation
CHEBI:9241

Additional References

Wikipedia:Spironolactone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SUSPENSION
labeler_name
Tianjin Jinjin Pharmaceutical Co.,Ltd
application_number
ANDA086513
product_ndc
50090-6408
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
9997
oboInOwl#hasDbXref
Wikipedia:Spironolactone
oboInOwl#hasAlternativeId
CHEBI:45692
oboInOwl#id
CHEBI:9241
generic_name
Spironolactone Micronized
brand_name
Spironolactone and Hydrochlorothiazide
brand_name_base
Spironolactone and Hydrochlorothiazide
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35703
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
route
ORAL
package_ndc
53489-143-10
spl_id
e730d821-976f-4dc5-a98a-4fa3c9539565
listing_expiration_date
20241231
marketing_start_date
19790803
package_description
2500 g in 1 PAIL (62991-1211-6)
manufacturer_name
REMEDYREPACK INC.
package_marketing_start_date
20230407
active_ingredient_strength
25 mg/5mL
active_ingredient_name
SPIRONOLACTONE
nui
N0000011310
upc
0369238202786
spl_set_id
7ef0c2bb-9657-419e-848c-858893be50bc
has_treatment
http://purl.obolibrary.org/obo/DOID_682
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38383
owl#annotatedSource
t321247
owl#someValuesFrom
t929134
rxcui
200825
unii
27O7W4T232
core#notation
CHEBI:9241
pharm_class_epc
Aldosterone Antagonist [EPC]
pharm_class
Aldosterone Antagonists [MoA]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
pharm_class_moa
Aldosterone Antagonists [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class