Discuss This Drug

Ketotifen

CHEBI:CHEBI_92511

Definition

An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Chemical Information

Molecular Formula
C19H19NOS
Molecular Mass
309.427
Charge
0
SMILES
CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1
InChI
InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3
InChIKey
ZCVMWBYGMWKGHF-UHFFFAOYSA-N

Alternative Names

  • 10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one
  • 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
  • ketotifen
  • ketotifene
  • ketotifeno
  • ketotifenum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6146
oboInOwl#hasDbXref
Wikipedia:Ketotifen
core#notation
CHEBI:92511

Additional References

Wikipedia:Ketotifen

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
311237
package_marketing_start_date
30-JAN-17
manufacturer_name
PERRIGO DIRECT INC.
package_description
1 kg in 1 CONTAINER (51927-0014-0)
unii
HBD503WORO
spl_set_id
5fccbb63-7859-484c-b7b3-9de711364c09
package_ndc
49452-3923-4
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6146
oboInOwl#hasDbXref
Wikipedia:Ketotifen
oboInOwl#id
CHEBI:92511
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SOLUTION/ DROPS
product_type
BULK INGREDIENT
labeler_name
PERRIGO DIRECT INC.
generic_name
ketotifen fumarate solution
brand_name
Ketotifen Fumarate Ophthalmic Solution
brand_name_base
Ketotifen Fumarate Ophthalmic Solution
product_ndc
51927-0014
application_number
ANDA077958
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_140417
listing_expiration_date
20241231
marketing_start_date
20121031
route
OPHTHALMIC
spl_id
f18da66f-1692-bd42-e053-2995a90aaa14
core#notation
CHEBI:92511
pharm_class
Histamine-1 Receptor Inhibitor [EPC]
active_ingredient_strength
.35 mg/mL
active_ingredient_name
KETOTIFEN FUMARATE
upc
0305361252403
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4660
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_140417
owl#someValuesFrom
t3879746
owl#annotatedSource
t321276