Streptozocin

CHEBI:CHEBI_9288

Definition

An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

Chemical Information

Molecular Formula
C8H15N3O7
Molecular Mass
265.22072
Charge
0
SMILES
CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
InChIKey
ZSJLQEPLLKMAKR-GKHCUFPYSA-N

Alternative Names

  • 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose
  • 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
  • 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
  • estreptozocina
  • N-D-Glucosyl-(2)-N'-nitrosomethylurea
  • N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff
  • streptozocin
  • streptozocin
  • streptozocine
  • Streptozocinium
  • streptozocinum
  • Streptozotocin
  • Zanosar

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9288
DRON_00010000
10114
oboInOwl#hasDbXref
Wikipedia:Streptozocin

Additional References

Wikipedia:Streptozocin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:9288
pharm_class
Alkylating Drug [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10114
oboInOwl#hasDbXref
Wikipedia:Streptozocin
oboInOwl#id
CHEBI:9288
generic_name
Streptozocin
brand_name
Zanosar
brand_name_base
Zanosar
rxcui
207948
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
POWDER, FOR SOLUTION
active_ingredient_strength
1 g/10mL
route
INTRAVENOUS
pharm_class_moa
Alkylating Activity [MoA]
pharm_class_epc
Alkylating Drug [EPC]
nui
N0000175558
marketing_start_date
20031203
package_marketing_start_date
20031203
labeler_name
ESTEVE PHARMACEUTICALS, S.A.
manufacturer_name
ESTEVE PHARMACEUTICALS, S.A.
product_ndc
0703-4636
spl_id
086af066-2d97-4c11-9f8d-68eb4f7c29f3
active_ingredient_name
STREPTOZOCIN
package_ndc
0703-4636-01
package_description
10 mL in 1 VIAL (0703-4636-01)
unii
5W494URQ81
spl_set_id
15d161ed-9e7b-4c92-ba45-0556d2423e67
application_number
NDA050577
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_25212
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38399
owl#annotatedSource
t321206
owl#someValuesFrom
t3056168