Discuss This Drug

Sulindac

CHEBI:CHEBI_9352

Definition

A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.

Chemical Information

Molecular Formula
C20H17FO3S
Molecular Mass
356.41158
Charge
0
SMILES
CC1=C(CC(O)=O)c2cc(F)ccc2C\1=C/c1ccc(cc1)S(C)=O
InChI
InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-
InChIKey
MLKXDPUZXIRXEP-MFOYZWKCSA-N

Alternative Names

  • (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
  • {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid
  • cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
  • cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid
  • Clinoril
  • sulindac
  • Sulindac
  • sulindaco
  • Sulindacum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10237
oboInOwl#hasDbXref
Wikipedia:Sulindac
core#notation
CHEBI:9352

Additional References

Wikipedia:Sulindac

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

RO_0000087
http://purl.obolibrary.org/obo/CHEBI_66993
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10237
oboInOwl#hasDbXref
Wikipedia:Sulindac
oboInOwl#id
CHEBI:9352
generic_name
SULINDAC
brand_name
SULINDAC
brand_name_base
SULINDAC
product_type
BULK INGREDIENT
dosage_form
POWDER
marketing_category
BULK INGREDIENT
labeler_name
PuraCap Laboratories LLC dba Blu Pharmaceuticals
product_ndc
49452-7583
application_number
ANDA071891
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_15366
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20021008
spl_id
08a1008b-dc02-9bba-e063-6294a90aed7e
package_ndc
49452-7583-6
package_description
10000 g in 1 DRUM (49452-7583-6)
core#notation
CHEBI:9352
rxcui
198239
pharm_class
Non-Steroidal [CS]
manufacturer_name
PuraCap Laboratories LLC dba Blu Pharmaceuticals
active_ingredient_strength
1 kg/kg
nui
N0000175722
pharm_class_epc
Nonsteroidal Anti-inflammatory Drug [EPC]
pharm_class_moa
Cyclooxygenase Inhibitors [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
package_marketing_start_date
08-OCT-02
active_ingredient_name
SULINDAC
unii
184SNS8VUH
spl_set_id
eb7acb87-6565-4524-a91a-02064ea8bd1a
upc
0372789373010
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0111686
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38712
owl#annotatedSource
t321290
owl#someValuesFrom
t3000755