tamsulosin

CHEBI:CHEBI_9398

Definition

A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (R)-configuration. A specific alpha1 adrenoceptor antagonist used (generally as its hydrochloride salt, tamsulosin hydrochloride) in the treatment of prostatic hyperplasia, chronic prostatitis, urinary retention, and help with the passage of kidney stones.

Chemical Information

Molecular Formula
C20H28N2O5S
Molecular Mass
408.514
Charge
0
SMILES
C=1C=C(OCCN[C@@H](CC2=CC=C(C(=C2)S(N)(=O)=O)OC)C)C(=CC1)OCC
InChI
InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
InChIKey
DRHKJLXJIQTDTD-OAHLLOKOSA-N

Alternative Names

  • (-)-tamsulosin
  • (R)-(-)-tamsulosin
  • (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
  • 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide
  • tamsulosin
  • Tamsulosin
  • tamsulosina
  • tamsulosine
  • tamsulosinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9398
oboInOwl#hasDbXref
Wikipedia:Tamsulosin
DRON_00010000
77492

Additional References

Wikipedia:Tamsulosin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
0904-6401-89
spl_id
180060de-07ab-4cad-a02b-0b9631abbeb7
listing_expiration_date
20241231
marketing_start_date
20190416
labeler_name
Ascend Laboratories, LLC
package_description
90 CAPSULE in 1 BOTTLE (0904-6401-89)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
CAPSULE, GELATIN COATED
application_number
ANDA214730
product_ndc
61919-703
pharm_class
alpha-Adrenergic Blocker [EPC]
active_ingredient_strength
75 kg/75kg
active_ingredient_name
TAMSULOSIN HYDROCHLORIDE
upc
0368071487299
spl_set_id
49245aec-9a0f-459e-e054-00144ff8d46c
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4738
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108507
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6474
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_142544
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_142548
owl#someValuesFrom
t3000691
owl#annotatedSource
t321297
package_marketing_start_date
27-APR-10
core#notation
CHEBI:9398
rxcui
863671
manufacturer_name
RedPharm Drug. Inc.
unii
11SV1951MR
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Tamsulosin
DRON_00010000
77492
oboInOwl#id
CHEBI:9398
generic_name
Tamsulosin HCL
brand_name
FLOMAX
brand_name_base
FLOMAX
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37890
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_142544