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tazobactam

CHEBI:CHEBI_9421

Definition

A member of the class of penicillanic acids that is sulbactam in which one of the exocyclic methyl hydrogens is replaced by a 1,2,3-triazol-1-yl group; used (in the form of its sodium salt) in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.

Chemical Information

Molecular Formula
C10H12N4O5S
Molecular Mass
300.29100
Charge
0
SMILES
C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O
InChI
InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
InChIKey
LPQZKKCYTLCDGQ-WEDXCCLWSA-N

Alternative Names

  • (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda(6)-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,3S,5S)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
  • tazobactam
  • tazobactamum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9421
DRON_00010000
37617
oboInOwl#hasDbXref
Wikipedia:Tazobactam

Additional References

Wikipedia:Tazobactam

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:9421
rxcui
1659151
pharm_class
beta Lactamase Inhibitors [MoA]
active_ingredient_name
TAZOBACTAM
unii
UXA545ABTT
active_ingredient_strength
375 mg/50mL
package_marketing_start_date
18-JUN-20
manufacturer_name
Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
brand_name_suffix
in Galaxy Containers
spl_set_id
8ab9d90d-2f7f-4599-a44f-3d0a8f8ab623
upc
0302068860016
package_description
24 BAG in 1 BOX (0206-8861-02) / 50 mL in 1 BAG (0206-8861-01)
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
37617
oboInOwl#hasDbXref
Wikipedia:Tazobactam
oboInOwl#hasAlternativeId
CHEBI:45973
oboInOwl#id
CHEBI:9421
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, SOLUTION
route
INTRAVENOUS
marketing_start_date
19930201
labeler_name
Shandong Anshun Pharmaceutical Co., Ltd.
brand_name_base
Zosyn
application_number
NDA050750
generic_name
Tazobactam Sodium Sterile
product_ndc
52946-0925
spl_id
0dadf9b4-7ca5-4846-a51f-ec7e9116e4eb
package_ndc
52946-0925-0
brand_name
Zosyn in Galaxy Containers
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35625
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_9321
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_85193
has_treatment
http://purl.obolibrary.org/obo/DOID_0050365
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113873
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37290
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_85193
owl#someValuesFrom
t2995390
owl#annotatedSource
t321183