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tazobactam

CHEBI:CHEBI_9421

Definition

A member of the class of penicillanic acids that is sulbactam in which one of the exocyclic methyl hydrogens is replaced by a 1,2,3-triazol-1-yl group; used (in the form of its sodium salt) in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.

Chemical Information

Molecular Formula
C10H12N4O5S
Molecular Mass
300.29100
Charge
0
SMILES
C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O
InChI
InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
InChIKey
LPQZKKCYTLCDGQ-WEDXCCLWSA-N

Alternative Names

  • (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda(6)-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,3S,5S)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
  • tazobactam
  • tazobactamum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
37617
oboInOwl#hasDbXref
Wikipedia:Tazobactam
core#notation
CHEBI:9421

Additional References

Wikipedia:Tazobactam

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
37617
oboInOwl#hasDbXref
Wikipedia:Tazobactam
oboInOwl#hasAlternativeId
CHEBI:45973
oboInOwl#id
CHEBI:9421
core#notation
CHEBI:9421
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35625
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http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_9321
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_85193
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http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0050365
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113873
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37290
chebi#is_conjugate_base_of
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owl#someValuesFrom
t2995390
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t321183