Discuss This Drug

Tetrabenazine

CHEBI:CHEBI_9467

Definition

A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia.

Alternative Names

  • TBZ
  • 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
  • 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
  • 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
  • Nitoman
  • rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
  • Ro 1-9569
  • tetrabenazina
  • tetrabenazine
  • Tetrabenazine
  • tetrabenazinum
  • Xenazine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Tetrabenazine
DRON_00010000
10390
core#notation
CHEBI:9467

Additional References

Wikipedia:Tetrabenazine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20081124
spl_id
1b073ed7-167e-4511-9a2f-70a63e610334
package_ndc
57821-014-01
package_description
30 kg in 1 BAG (57821-014-01)
labeler_name
Oceanside Pharmaceuticals
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Tetrabenazine
DRON_00010000
10390
oboInOwl#id
CHEBI:9467
generic_name
TETRABENAZINE
brand_name
TETRABENAZINE
brand_name_base
TETRABENAZINE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
TABLET, COATED
product_ndc
57821-014
application_number
ANDA208826
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35640
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_64030
core#notation
CHEBI:9467
rxcui
805466
active_ingredient_strength
25 kg/25kg
package_marketing_start_date
20081124
active_ingredient_name
TETRABENAZINE, (+)-
manufacturer_name
Precision Dose Inc.
unii
Z9O08YRN8O
spl_set_id
acf78d97-fca5-49aa-8683-6db7396da72f
nui
N0000190855
pharm_class_epc
Vesicular Monoamine Transporter 2 Inhibitor [EPC]
pharm_class
Vesicular Monoamine Transporter 2 Inhibitors [MoA]
pharm_class_moa
Vesicular Monoamine Transporter 2 Inhibitors [MoA]
upc
0327241176135
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0060944
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113753
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38899
owl#annotatedSource
t324756
owl#someValuesFrom
t996749