Discuss This Drug

torsemide

CHEBI:CHEBI_9637

Definition

An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.

Chemical Information

Molecular Formula
C16H20N4O3S
Molecular Mass
348.420
Charge
0
SMILES
C=1(C(NC=2C=C(C=CC2)C)=CC=NC1)S(NC(NC(C)C)=O)(=O)=O
InChI
InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
InChIKey
NGBFQHCMQULJNZ-UHFFFAOYSA-N

Alternative Names

  • 1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
  • 4-(3-methylanilino)-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide
  • AC 4464
  • AC-4464
  • AC4464
  • BM 02015
  • BM-02.015
  • BM-02015
  • BM02.015
  • BM02015
  • Demadex
  • JDL 464
  • JDL-464
  • Luprac
  • N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
  • N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
  • N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
  • torasemida
  • torasemide
  • torasemidum
  • Torem
  • Torsemide
  • Unat

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9637
DRON_00010000
38413
oboInOwl#hasDbXref
Wikipedia:Torasemide

Additional References

Wikipedia:Torasemide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020327
package_description
90 TABLET, FILM COATED in 1 BOTTLE (73502-786-08)
package_ndc
63809-2744-1
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
POWDER
labeler_name
Bioindustria L.I.M. SpA
marketing_start_date
19930823
application_number
ANDA076943
product_ndc
72166-010
listing_expiration_date
20241231
route
ORAL
spl_id
fc630aac-990b-e3c1-e053-6394a90af178
core#notation
CHEBI:9637
pharm_class_epc
Loop Diuretic [EPC]
pharm_class
Increased Diuresis at Loop of Henle [PE]
pharm_class_pe
Increased Diuresis at Loop of Henle [PE]
upc
0373502287126
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t324790
owl#someValuesFrom
t3011115
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
38413
oboInOwl#hasDbXref
Wikipedia:Torasemide
oboInOwl#id
CHEBI:9637
generic_name
Torsemide (Mod 1)
brand_name
SOAANZ
brand_name_base
SOAANZ
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35674
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_34385
rxcui
2589887
active_ingredient_strength
50 kg/50kg
manufacturer_name
REMEDYREPACK INC.
nui
N0000175590
package_marketing_start_date
20220124
active_ingredient_name
TORSEMIDE
unii
W31X2H97FB
spl_set_id
f24151c8-02cd-4b07-a7fd-796903210aba