Discuss This Drug

Tramadol

CHEBI:CHEBI_9648

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.

Chemical Information

Molecular Formula
C16H25NO2
Molecular Mass
263.37520
Charge
0

Alternative Names

  • (+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
  • CG-315E
  • E-265
  • rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
  • tramadol
  • tramadolum
  • U-26225A

Drug Classification

  • racemate

    CHEBI:60911

    View Class →
  • t323485
  • t323535
  • t323603
  • t323616
  • t323726
  • t323752
  • t323812
  • t323981
  • t324053
  • t324060
  • t324250
  • t324325
  • t324462
  • t324512
  • t324573
  • t324586
  • t324592
  • t324635
  • t324667
  • t324682
  • t324784

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9648
oboInOwl#hasDbXref
Reaxys:2943832
DRON_00010000
10689

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

dosage_form
TABLET, COATED
product_ndc
61281-8500
package_ndc
71610-398-40
spl_id
1f94c73e-1add-bbd4-e063-6294a90a7a37
listing_expiration_date
20241231
marketing_start_date
20110122
labeler_name
Virupaksha Organics Limited
brand_name_base
TRAMADOL HCL
package_description
60 TABLET, COATED in 1 BOTTLE (80425-0274-3)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA091607
package_marketing_start_date
22-JAN-11
route
ORAL
core#notation
CHEBI:9648
dea_schedule
CIV
pharm_class
Opioid Agonist [EPC]
brand_name_suffix
Extended-Release
upc
0347335860832
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
spl_set_id
0742ec44-f8b4-45c5-a36e-2638bdaa2e44
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:2943832
DRON_00010000
10689
oboInOwl#id
CHEBI:9648
generic_name
tramadol hcl
brand_name
TRAMADOL HCL ER
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59282
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_75725
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect34371
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_75736
owl#someValuesFrom
t3847950
owl#annotatedSource
t324727
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_75736
rxcui
2692878
manufacturer_name
Palmetto Pharmaceuticals, Inc.
unii
362O9ITL9D
active_ingredient_strength
50 kg/50kg
active_ingredient_name
ACETAMINOPHEN
has_treatment
http://purl.obolibrary.org/obo/DOID_573