Triamcinolone
CHEBI:CHEBI_9667
Definition
A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.
Chemical Information
- Molecular Formula
- C21H27FO6
- Molecular Mass
- 394.43390
- Charge
- 0
- SMILES
- [H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
- InChI
- InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
- InChIKey
- GFNANZIMVAIWHM-OBYCQNJPSA-N
Alternative Names
- (11beta,16alpha)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 11beta,16alpha,17alpha,21-tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione
- 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9alpha-fluoro-16alpha-hydroxyprednisolone
- Fluoxyprednisolone
- triamcinolona
- triamcinolone
- triamcinolonum
Drug Classification
-
t324560
-
glucocorticoidView Class →
CHEBI:24261
-
20-oxo steroidView Class →
CHEBI:36885
-
21-hydroxy steroidView Class →
CHEBI:35344
-
primary alpha-hydroxy ketoneView Class →
CHEBI:139590
-
tertiary alpha-hydroxy ketoneView Class →
CHEBI:139592
-
17alpha-hydroxy steroidView Class →
CHEBI:35342
-
16alpha-hydroxy steroidView Class →
CHEBI:16799
-
3-oxo-Delta(4) steroidView Class →
CHEBI:47909
-
C21-steroid hormoneView Class →
CHEBI:64600
-
11beta-hydroxy steroidView Class →
CHEBI:35346
-
fluorinated steroidView Class →
CHEBI:50830
-
t323648
-
t323758
-
t324144
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 10759
- oboInOwl#hasDbXref
- Wikipedia:Triamcinolone
- core#notation
- CHEBI:9667
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_ndc
- 51927-1326-0
- product_ndc
- 51927-1326
- brand_name_base
- Signature Care Nasal Allergy
- listing_expiration_date
- 20241231
- spl_id
- 548ceaef-8634-4719-bd96-2ad393df1e0b
- marketing_start_date
- 20180519
- labeler_name
- Pacira Pharmaceuticals, Inc.
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 10759
- oboInOwl#hasDbXref
- Wikipedia:Triamcinolone
- oboInOwl#id
- CHEBI:9667
- generic_name
- Triamcinolone acetonide crystallized sterile
- brand_name
- Triasil
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50857
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_8386
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00000067
- route
- INTRA-ARTERIAL
- package_marketing_start_date
- 01-FEB-99
- package_description
- 1 TUBE in 1 CARTON (0316-0175-15) / 15 g in 1 TUBE
- dosage_form
- INJECTION, POWDER, FOR SUSPENSION, EXTENDED RELEASE
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- application_number
- NDA208845
- core#notation
- CHEBI:9667
- rxcui
- 2665617
- manufacturer_name
- MidAmerica Pharmaceuticals
- active_ingredient_strength
- .1 mg/.1g
- active_ingredient_name
- TRIAMCINOLONE HEXACETONIDE
- spl_set_id
- c8000539-125f-f0dd-2f69-580eea235a77
- unii
- I7GT1U99Y9
- pharm_class_moa
- Corticosteroid Hormone Receptor Agonists [MoA]
- pharm_class
- Corticosteroid [EPC]
- pharm_class_epc
- Corticosteroid [EPC]
- nui
- N0000175450
- upc
- 0382804071302
- brand_name_suffix
- 2%
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- Name
- http://purl.obolibrary.org/obo/DOID_0040068
- has_treatment
- http://purl.obolibrary.org/obo/DOID_9598
- owl#annotatedSource
- t324776
- owl#someValuesFrom
- t3349758