Discuss This Drug

Triamterene

CHEBI:CHEBI_9671

Definition

Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.

Chemical Information

Molecular Formula
C12H11N7
Molecular Mass
253.263
Charge
0
SMILES
C1=CC=C(C=C1)C2=NC3=C(N=C2N)N=C(N=C3N)N
InChI
InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
InChIKey
FNYLWPVRPXGIIP-UHFFFAOYSA-N

Alternative Names

  • 6-phenylpteridine-2,4,7-triamine
  • triamterena
  • triamterene
  • triamterenum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Triamterene
DRON_00010000
10763
core#notation
CHEBI:9671

Additional References

Wikipedia:Triamterene

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Triamterene
DRON_00010000
10763
oboInOwl#hasAlternativeId
CHEBI:93604
oboInOwl#id
CHEBI:9671
brand_name
TRIAMTERENE AND HYDROCHLOROTHIAZIDE
brand_name_base
TRIAMTERENE AND HYDROCHLOROTHIAZIDE
generic_name
TRIAMTERENE AND HYDROCHLOROTHIAZIDE
product_ndc
71335-2338
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38633
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
spl_id
8944dd71-32b9-4558-a1cc-1eeb4ca9fab2
package_ndc
68788-8700-3
marketing_start_date
20140530
package_marketing_start_date
23-SEP-93
manufacturer_name
Concordia Pharmaceuticals Inc.
package_description
90 TABLET in 1 BOTTLE (71335-2338-3)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
labeler_name
Concordia Pharmaceuticals Inc.
application_number
ANDA211581
core#notation
CHEBI:9671
pharm_class_epc
Potassium-sparing Diuretic [EPC]
pharm_class
Decreased Renal K+ Excretion [PE]
pharm_class_pe
Decreased Renal K+ Excretion [PE]
pharm_class_cs
Thiazides [CS]
upc
0366993831022
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
208675
active_ingredient_strength
1 kg/kg
active_ingredient_name
TRIAMTERENE
unii
WS821Z52LQ
nui
N0000175418
spl_set_id
f3bc491a-961d-4a38-8a55-c4a03be05b74
has_treatment
http://purl.obolibrary.org/obo/DOID_2961
owl#annotatedSource
t324708
owl#someValuesFrom
t1098055