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Tromethamine

CHEBI:CHEBI_9754

Definition

A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.

Chemical Information

Molecular Formula
C4H11NO3
Molecular Mass
121.13500
Charge
0
SMILES
NC(CO)(CO)CO
InChI
InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChIKey
LENZDBCJOHFCAS-UHFFFAOYSA-N

Alternative Names

  • 1,1,1-tris(hydroxymethyl)methanamine
  • 2-Amino-2-(hydroxymethyl)-1,3-propanediol
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol
  • aminotris(hydroxymethyl)methane
  • THAM
  • Tris
  • Tris amino
  • Tris base
  • Tris buffer
  • Tris-base
  • tris(hydroxymethyl)aminomethane
  • Trizma
  • Trometamol
  • Tromethamine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Tris
DRON_00010000
10865
core#notation
CHEBI:9754

Additional References

Wikipedia:Tris

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Additional Attributes

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Wikipedia:Tris
DRON_00010000
10865
oboInOwl#id
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CHEBI:9754
chebi#is_conjugate_base_of
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RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35225
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http://www.w3.org/2002/07/owl#Class
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t324691