trovafloxacin
CHEBI:CHEBI_9763
Definition
A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure.
Chemical Information
- Molecular Formula
- C20H15F3N4O3
- Molecular Mass
- 416.35330
- Charge
- 0
- SMILES
- N[C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F
- InChI
- InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+
- InChIKey
- WVPSKSLAZQPAKQ-CDMJZVDBSA-N
Alternative Names
- 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
- trovafloxacin
- trovafloxacine
- trovafloxacino
- trovafloxacinum
Drug Classification
-
monocarboxylic acidView Class →
CHEBI:25384
-
difluorobenzeneView Class →
CHEBI:38582
-
1,8-naphthyridine derivativeView Class →
CHEBI:73537
-
quinolone antibioticView Class →
CHEBI:86324
-
fluoroquinolone antibioticView Class →
CHEBI:87211
-
tertiary amino compoundView Class →
CHEBI:50996
-
primary amino compoundView Class →
CHEBI:50994
-
azabicycloalkaneView Class →
CHEBI:38295
-
amino acidView Class →
CHEBI:33709
-
Amino AcidsView Class →
CHEBI:33709
-
t324051
-
t324201
-
t324267
-
t324452
-
t324787
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 115552
- oboInOwl#hasDbXref
- Wikipedia:Trovafloxacin
- core#notation
- CHEBI:9763
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 115552
- oboInOwl#hasDbXref
- Wikipedia:Trovafloxacin
- oboInOwl#id
- CHEBI:9763
- core#notation
- CHEBI:9763
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59517
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_77569
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect34742
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_77569
- owl#someValuesFrom
- t840083
- owl#annotatedSource
- t324785