valsartan
CHEBI:CHEBI_9927
Definition
A monocarboxylic acid amide consisting of L-valine in which the amino hydrogens have been replaced by a pentanoyl and a [2'-(1H-tetrazol-5-yl)biphenyl]-4-yl]methyl group. It exhibits antihypertensive activity.
Chemical Information
- Molecular Formula
- C24H29N5O3
- Molecular Mass
- 435.51896
- Charge
- 0
- SMILES
- CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@@H](C(C)C)C(O)=O
- InChI
- InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
- InChIKey
- ACWBQPMHZXGDFX-QFIPXVFZSA-N
Alternative Names
- (S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
- Diovan
- N-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
- N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
- N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
- valsartan
Drug Classification
-
monocarboxylic acidView Class →
CHEBI:25384
-
monocarboxylic acid amideView Class →
CHEBI:29347
-
biphenylyltetrazoleView Class →
CHEBI:48420
-
t323615
-
t323684
-
t324193
-
t324213
-
t324505
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 69749
- oboInOwl#hasDbXref
- Wikipedia:Valsartan
- core#notation
- CHEBI:9927
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- TABLET, COATED
- application_number
- ANDA203000
- product_ndc
- 0078-0472
- listing_expiration_date
- 20241231
- spl_id
- acdb8b8d-0858-4805-bc6d-14cf1e135f41
- marketing_start_date
- 20190502
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 69749
- oboInOwl#hasDbXref
- Wikipedia:Valsartan
- oboInOwl#id
- CHEBI:9927
- brand_name
- VALSARTAN AND HYDROCHLOROTHIAZIDE
- brand_name_base
- VALSARTAN AND HYDROCHLOROTHIAZIDE
- generic_name
- Valsartan Disodium
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_61016
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00724207
- package_ndc
- 64220-153-09
- route
- ORAL
- labeler_name
- Zhuhai Rundu Pharmaceutical Co., Ltd.
- rxcui
- 1996254
- manufacturer_name
- Lifsa Drugs LLC
- unii
- 80M03YXJ7I
- spl_set_id
- a9098fc6-3d2a-404f-a4cd-2e181ebbd626
- package_marketing_start_date
- 20211005
- package_description
- 50 kg in 1 DRUM (64220-153-09)
- pharm_class_epc
- Angiotensin 2 Receptor Blocker [EPC]
- pharm_class
- Angiotensin 2 Receptor Blocker [EPC]
- pharm_class_pe
- Increased Diuresis [PE]
- pharm_class_cs
- Thiazides [CS]
- pharm_class_moa
- Angiotensin 2 Receptor Antagonists [MoA]
- upc
- 0300780472340
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- core#notation
- CHEBI:9927
- active_ingredient_name
- VALSARTAN
- active_ingredient_strength
- 400 kg/400kg
- nui
- N0000175561
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0060218
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect39391
- owl#annotatedSource
- t324710
- owl#someValuesFrom
- t3259152