4 free views remaining today

nickel allergic asthma

ICD-10 Codes

Related ICD-10:

Description

Nickel Allergic Asthma: A Rare but Possible Condition

Nickel allergy can manifest in various ways, including skin reactions and respiratory symptoms. In rare cases, a nickel allergy can lead to asthma-like respiratory symptoms.

  • Respiratory Symptoms: Individuals with nickel allergic asthma may experience increased variations in peak expiratory flow rates after exposure to nickel.
  • Asthma-Like Symptoms: The condition can cause respiratory symptoms similar to those experienced by people with asthma, such as wheezing and shortness of breath.
  • At-Risk Groups: People with ear or body piercings, individuals who work in metal-plating factories, and those with a history of nickel exposure are at higher risk for developing nickel allergic asthma.

Symptoms and Signs

  • Inflammation of the skin at an area that comes into regular contact with nickel
  • Reddened patch of skin with raised bumps (papules) or small blisters (vesicles)
  • Edema (swelling)

Prevention and Treatment

While there is limited information available on treating nickel allergic asthma, it's essential to avoid exposure to nickel-containing products. If you suspect you have a nickel allergy, consult a healthcare professional for proper diagnosis and treatment.

References:

[10] A 28-year-old man developed asthma 10 years after working in a metal-plating factory. [11] In rare cases, a nickel allergy can also lead to asthma-like respiratory symptoms. [8] Nickel allergy is the most prevalent contact allergy. It belongs to a different hypersensitivity type to asthma and rhinoconjunctivitis. [15] Occupational asthma from nickel sensitivity was confirmed in a male worker (SB) by allergy skin tests and inhalational ...

Additional Characteristics

  • Nickel allergic asthma can manifest with respiratory symptoms such as increased variations in peak expiratory flow rates after exposure to nickel.
  • Asthma-like symptoms can include wheezing and shortness of breath.
  • Inflammation of the skin at an area that comes into regular contact with nickel may occur.
  • Reddened patch of skin with raised bumps (papules) or small blisters (vesicles) can be a symptom.
  • Edema (swelling) is another possible sign.

Signs and Symptoms

Symptoms of Nickel Allergy

Nickel allergy can manifest in various ways, but it's essential to note that it's not directly related to asthma. However, if you have a nickel allergy, you may experience skin symptoms that can be similar to those experienced by people with asthma.

  • Skin Symptoms: The primary signs and symptoms of a nickel allergy include:
    • Redness and itching or burning sensations on the skin
    • Blisters, cracked skin, and dry patches
    • Swelling of the skin, which may lead to crusts and scabs [1]
    • In severe cases, the symptoms can be disabling and affect daily life [2]

Important Note: Nickel allergy is not directly linked to asthma. Asthma is a respiratory condition characterized by inflammation, airway obstruction, and spasm of the bronchial tubes. If you experience symptoms like wheezing, coughing, shortness of breath, or chest tightness, it's essential to consult with a healthcare professional for proper diagnosis and treatment.

Distinguishing Nickel Allergy from Asthma

While both conditions can cause discomfort, they have distinct characteristics:

  • Nickel Allergy: Primarily affects the skin, causing redness, itching, blisters, and dry patches.
  • Asthma: Affects the respiratory system, leading to symptoms like wheezing, coughing, shortness of breath, or chest tightness.

If you suspect a nickel allergy, consult with a healthcare professional for proper diagnosis and treatment. They may recommend a patch test to confirm the presence of a nickel allergy [3].

References:

[1] - Context 1: May 23, 2024 [2] - Context 2: February 11, 2022 [3] - Context 3: October 21, 2022

Additional Symptoms

  • Redness and itching or burning sensations on the skin
  • Blisters, cracked skin, and dry patches
  • Swelling of the skin, which may lead to crusts and scabs

Diagnostic Tests

Based on the provided context, it appears that there are some diagnostic tests mentioned for nickel allergy, but not specifically for nickel allergic asthma.

However, I can provide some general information about diagnostic tests for allergies and asthma.

  • Skin Prick Test: This test involves pricking the skin with a small amount of an allergen, such as nickel, to see if it triggers an allergic reaction. [2][3]
  • Blood Tests: Blood tests can measure the levels of IgE antibodies in the blood, which can indicate an allergy. However, these tests are not specific to nickel allergy and may not be useful for diagnosing asthma. [2]
  • Spirometry: This test measures lung function and can help diagnose respiratory conditions such as asthma. However, it is not a diagnostic test for nickel allergy specifically.
  • Bronchoconstriction Test: This test involves inhaling a substance that causes the airways to constrict, and measuring how much they constrict. It can be used to diagnose asthma, but not specifically nickel allergic asthma.

It's worth noting that nickel allergic asthma is not a commonly discussed topic in medical literature, and it's possible that there may not be specific diagnostic tests for this condition.

If you're looking for information on diagnosing nickel allergy or asthma, I'd be happy to provide more general information. However, if you have any further questions about nickel allergic asthma specifically, I may not be able to provide a detailed answer based on the provided context.

Additional Diagnostic Tests

  • Blood Tests
  • Skin Prick Test
  • Spirometry
  • Bronchoconstriction Test

Treatment

Based on the available information, it appears that there are some treatment options for nickel allergy, but they may not be directly related to asthma.

  • Oral administration of nickel sulfate has been shown to reduce the degree of contact dermatitis in nickel-allergic patients [5].
  • Topical medications such as corticosteroid and nonsteroidal creams can be applied directly to inflamed patches of skin [3].
  • Oral corticosteroids are also available for more severe symptoms [3].

However, it's worth noting that the context provided does not specifically mention asthma. The information seems to focus on contact dermatitis and other skin-related reactions.

If you're looking for information on drug treatment for nickel allergic asthma, I couldn't find any relevant information in the search results. However, I can suggest searching again or asking something else if you'd like.

References: [3] - Topical medications: Corticosteroid and nonsteroidal creams can be applied directly to inflamed patches of skin

Recommended Medications

  • Oral corticosteroids
  • Oral administration of nickel sulfate
  • Topical corticosteroid and nonsteroidal creams

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Nickel Allergic Asthma

Nickel allergy can manifest in various ways, including respiratory symptoms that mimic asthma. To determine if a patient's asthma-like symptoms are caused by a nickel allergy, it is essential to consider the following differential diagnoses:

  • Asthma: A chronic inflammatory disease of the airways characterized by recurring episodes of wheezing, shortness of breath, chest tightness, and coughing.
  • Allergic rhinitis: An allergic reaction that occurs when allergens such as pollen, dust mites, or pet dander enter the nasal passages, causing symptoms like sneezing, runny nose, and congestion.
  • Chronic obstructive pulmonary disease (COPD): A progressive lung disease characterized by airflow limitation, making it difficult to breathe.
  • Eosinophilic pneumonia: A rare condition where eosinophils accumulate in the lungs, causing inflammation and respiratory symptoms.

Key differences between nickel allergic asthma and other conditions

  • Nickel allergy is a type of contact dermatitis, which can cause skin irritation, redness, and blistering at the site of contact. In contrast, asthma-like symptoms caused by nickel allergy are not directly related to skin exposure.
  • Respiratory symptoms in nickel allergy are often accompanied by skin manifestations, such as itchy rashes or blisters, whereas asthma and COPD typically do not present with skin symptoms.
  • Nickel allergy can cause systemic reactions, including respiratory symptoms, whereas allergic rhinitis is primarily a localized reaction.

Diagnostic approaches

To diagnose nickel allergic asthma, healthcare providers may use the following diagnostic approaches:

  • Patch testing: A method that involves applying small amounts of potential allergens to the skin and observing for any adverse reactions.
  • Blood tests: Such as radioallergosorbent test (RAST) or enzyme-linked immunosorbent assay (ELISA), which can detect specific antibodies against nickel in the blood.
  • Skin prick testing: A method that involves pricking the skin with a small amount of allergen and observing for any reaction.

References

  1. by L Kolberg · 2020 · Cited by 20 — Nickel allergy is the most prevalent contact allergy. It belongs to a different hypersensitivity type to asthma and rhinoconjunctivitis.
  2. by S Brera · 2005 · Cited by 37 — Nickel sulphate more frequently determines allergic dermatitis due to contact (contact eczema); less known are nasal inflammation (rhinitis) and bronchial ...
  3. In rare cases, a nickel allergy can

Additional Information

rdf-schema#domain
https://w3id.org/def/predibionto#has_symptom_46
owl#annotatedSource
t327555
oboInOwl#hasOBONamespace
disease_ontology
oboInOwl#id
DOID:0040045
core#notation
DOID:0040045
oboInOwl#hasExactSynonym
allergic asthma to Ni
IAO_0000115
An allergic asthma that has_allergic_trigger nickel atom.
rdf-schema#label
nickel allergic asthma
rdf-schema#subClassOf
t328246
oboInOwl#inSubset
http://purl.obolibrary.org/obo/doid#DO_IEDB_slim
RO_0001022
http://purl.obolibrary.org/obo/CHEBI_28112
relatedICD
http://example.org/icd10/J63.5
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
Test_Name
t4195500

Medical Disclaimer: The information provided on this website is for general informational and educational purposes only.

It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.