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endothrix infectious disease

ICD-10 Codes

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Description

Endothrix Infectious Disease: A Dermatophyte Infection of the Hair

Endothrix infectious disease, also known as endothrix tinea capitis, is a type of fungal infection that affects the hair shaft and internalizes into the hair cell. This condition is caused by dermatophytes, a group of fungi that have a predilection for keratinized tissues such as hair, skin, and nails.

Characteristics of Endothrix Infectious Disease

  • The disease is characterized by an invasion of the hair shaft by fungal spores, which internalize into the hair cell.
  • This type of infection can lead to a range of clinical manifestations, including mild scaling to severe hair loss.
  • Endothrix infections are primarily caused by dermatophytes, such as Ascomycota fungi.

Key Features

  • The disease is confined to the hair shaft and does not affect the surrounding skin or scalp.
  • Endothrix infections do not fluoresce under an ultraviolet Wood's lamp, in contrast to exothrix (ectothrix) infections which may fluoresce bright green or yellow-green.
  • The infection can be identified by examining the hair shaft under a microscope, where fungal spores and arthroconidia can be seen.

Summary

In summary, endothrix infectious disease is a type of dermatophyte infection that affects the hair shaft and internalizes into the hair cell. This condition is characterized by an invasion of the hair shaft by fungal spores, leading to clinical manifestations such as mild scaling to severe hair loss. The disease can be identified by examining the hair shaft under a microscope and does not fluoresce under an ultraviolet Wood's lamp.

References

  • [1] Endothrix infectious disease is a type of tinea capitis caused by Ascomycota fungi known as dermatophytes. These fungi produce arthroconidia within the hair shaft exclusively. (Context 3)
  • [2] The disease is characterized by an invasion of the hair shaft by fungal spores, which internalize into the hair cell. (Context 5)
  • [3] Endothrix infections are primarily caused by dermatophytes, such as Ascomycota fungi. (Context 14)

Additional Characteristics

  • a type of fungal infection that affects the hair shaft and internalizes into the hair cell
  • characterized by an invasion of the hair shaft by fungal spores, leading to clinical manifestations such as mild scaling to severe hair loss
  • can be identified by examining the hair shaft under a microscope and does not fluoresce under an ultraviolet Wood's lamp
  • primarily caused by dermatophytes, such as Ascomycota fungi

Signs and Symptoms

Endothrix Infection Signs and Symptoms

Endothrix infection, also known as endothrix fungal infection, is a condition where dermatophytes invade the hair shaft without damaging the cuticle. This type of infection can be caused by anthropophilic species such as Trichophyton.

  • Dry scaling: Similar to dandruff, but usually accompanied by moth-eaten hair loss [6]
  • Black dots: Hairs are broken off at the scalp surface, which is scaly [7]
  • Smooth areas of hair loss: Characterized by a smooth, flat appearance on the scalp [7]

These symptoms can vary in severity and may be accompanied by other signs such as redness, itchiness, or inflammation. It's essential to note that endothrix infection can be a sign of a more severe underlying condition, so prompt medical attention is necessary for proper diagnosis and treatment.

References: [6] - [6] refers to the context number 6 where it is mentioned that Endothrix infection is a condition in which dermatophytes invade hair shaft without damaging cuticle. It may be caused by anthropophilic species such as Trichophyton. [7] - [7] refers to the context number 7 where it is mentioned that Dry scaling โ€“ like dandruff but usually with moth-eaten hair loss ยท Black dots โ€“ the hairs are broken off at the scalp surface, which is scaly ยท Smooth areas of hair loss

Additional Symptoms

Diagnostic Tests

Endothrix infections, also known as endothrix fungal infections, can be diagnosed through various diagnostic tests.

Microscopic Examination The diagnosis of endothrix infections typically begins with a microscopic examination of the affected area. This involves examining skin, hair, and nail samples under a microscope to detect the presence of fungal hyphae and air spaces within the hair shafts [2]. A potassium hydroxide (KOH) smear is often used to dissolve the keratin in the hair shaft, making it easier to visualize the fungal elements.

Culture In addition to microscopic examination, culture tests are also commonly used to diagnose endothrix infections. This involves growing a sample of the affected tissue in a laboratory setting to isolate and identify the causative fungus [4].

Other Diagnostic Methods Other diagnostic methods for endothrix infections include:

  • Dermoscopy: A non-invasive technique that uses a dermatoscope to examine the skin, hair, and nails. Dermoscopy can be used for both diagnosis and monitoring of infections during treatment [3].
  • Biopsy: A biopsy may be performed in some cases to obtain a sample of tissue for further examination.
  • Molecular Biology Tests: Molecular biology tests, such as PCR (polymerase chain reaction), can also be used to diagnose endothrix infections by detecting the genetic material of the causative fungus.

It's worth noting that the diagnosis of endothrix infections often requires a combination of these diagnostic methods. A healthcare professional will typically use a combination of clinical examination, microscopic examination, and culture tests to confirm the diagnosis [6].

References: [1] Moskaluk, AE (2022) - Cited by 58 [2] Howell, SA (2023) - Cited by 8 [3] Moskaluk, AE (2022) - Cited by 58 [4] Howell, SA (2023) - Cited by 8 [5] Howell, SA (2023) - Cited by 8 [6] Howell, SA (2023) - Cited by 8

Additional Diagnostic Tests

  • Biopsy
  • Microscopic Examination
  • Culture
  • Dermoscopy
  • Molecular Biology Tests

Treatment

Treatment Options for Endothrix Infections

Endothrix infections, also known as tinea capitis, are a type of fungal infection that affects the scalp and hair shafts. The treatment options for endothrix infections typically involve oral antifungal medications.

  • Griseofulvin: This is a commonly used medication to treat endothrix infections in children and adults. It has been found to be effective against Trichophyton species, which are the most common causative agents of endothrix infections [3][13].
  • **Itracon

๐Ÿ’Š Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Endothrix Infections

Endothrix infections, also known as endothrix folliculitis, are a type of fungal infection that affects the hair shaft and scalp. The differential diagnosis for endothrix infections is extensive and includes various conditions that can cause similar symptoms.

  • Dissecting folliculitis (folliculitis decalvans): This condition is characterized by inflammation of the hair follicles, leading to scarring and loss of hair [1].
  • Cellulitis: A bacterial infection of the skin and subcutaneous tissue that can cause redness, swelling, and pain in the affected area [2].
  • Bacterial folliculitis: An infection of the hair follicles caused by bacteria, which can lead to inflammation, pus formation, and scarring [3].
  • Secondary syphilis: A sexually transmitted disease that can cause a range of symptoms, including skin rashes, fever, and swollen lymph nodes [4].
  • Abscess: A pocket of pus that forms in the skin or subcutaneous tissue as a result of an infection [5].
  • Infected eczema: A type of skin inflammation caused by an allergic reaction or irritation, which can become infected with bacteria or fungi [6].

It's essential to note that endothrix infections are often misdiagnosed or confused with other conditions. Therefore, a thorough medical examination and diagnostic testing are necessary to confirm the diagnosis.

References:

[1] Context 3 [2] Context 2 [3] Context 5 [4] Context 2 [5] Context 7 [6] Context 8

Additional Differential Diagnoses

Additional Information

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