Discuss This Drug

Griseofulvin

CHEBI:CHEBI_27779

Definition

An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.

Chemical Information

Molecular Formula
C17H17ClO6
Molecular Mass
352.76598
Charge
0
SMILES
COc1cc(OC)c2C(=O)[C@]3(Oc2c1Cl)[C@H](C)CC(=O)C=C3OC
InChI
InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N

Alternative Names

  • (+)-griseofulvin
  • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
  • amudane
  • Curling factor
  • Fulcin
  • Fulvicin
  • Grifulvin
  • Grisactin
  • griseofulvin
  • griseofulvin
  • Griseofulvin
  • griseofulvina
  • griseofulvine
  • griseofulvinum
  • Grisovin
  • Grysio
  • Lamoryl
  • Likuden
  • Poncyl
  • Spirofulvin
  • Sporostatin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:27779
DRON_00010000
5021
oboInOwl#hasDbXref
Wikipedia:Griseofulvin

Additional References

Wikipedia:Griseofulvin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
package_marketing_start_date
01-MAY-07
manufacturer_name
Heritage Pharmaceuticals Inc d/b/a Avet Pharmaceuticals Inc
marketing_start_date
19710909
labeler_name
Actavis Pharma, Inc.
spl_id
0762048c-6f55-bff3-e063-6294a90abb66
package_ndc
49452-3363-6
package_description
25000 g in 1 DRUM (49452-3363-6)
core#notation
CHEBI:27779
rxcui
310600
active_ingredient_strength
125 mg/5mL
nui
N0000175848
pharm_class_pe
Decreased Mitosis [PE]
pharm_class
Decreased Mitosis [PE]
active_ingredient_name
GRISEOFULVIN
unii
32HRV3E3D5
spl_set_id
67e3ba3c-77e1-43b5-a93c-5bf5e3855780
pharm_class_epc
Tubulin Inhibiting Agent [EPC]
upc
0307130850049
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5021
oboInOwl#hasDbXref
Wikipedia:Griseofulvin
oboInOwl#hasAlternativeId
CHEBI:5546
oboInOwl#id
CHEBI:27779
generic_name
Griseofulvin (microsize)
brand_name
Griseofulvin MICROSIZE
brand_name_base
Griseofulvin MICROSIZE
product_type
BULK INGREDIENT
dosage_form
SUSPENSION
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
product_ndc
49452-3363
application_number
ANDA065438
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76964
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113590
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect12764
owl#annotatedSource
t159137
has_treatment
http://purl.obolibrary.org/obo/DOID_2409
owl#someValuesFrom
t825891