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dengue shock syndrome
ICD-10 Codes
Description
Dengue Shock Syndrome (DSS) is a severe and potentially life-threatening complication of dengue infection. It is characterized by:
- Circulatory collapse: A sudden drop in blood pressure, which can lead to inadequate blood flow to vital organs [7].
- Hypotension: Low blood pressure, typically defined as less than 90 mm Hg systolic or 60 mm Hg diastolic [4].
- Narrow pulse pressure: A narrow difference between the systolic and diastolic blood pressures (less than 20 mm Hg) [4].
- Shock: A critical condition where the body's vital organs do not receive enough oxygen and nutrients to function properly.
The symptoms of DSS can include:
- Sweaty, cool, and clammy skin
- Rapid pulse
- Lethargy, followed by restlessness and rapid deterioration [5].
- Abdominal pain and tenderness
- Vomiting
- Hematemesis (vomiting blood)
- Epistaxis (nosebleeds) or bleeding from the gums [2].
DSS typically occurs 2-6 days after the initial symptoms of dengue fever, which can include high fever, headache, body aches, nausea, and rash [8]. If left untreated, DSS can lead to severe complications, including organ failure and death.
References: [1] Not provided (no relevant information found) [2] Symptoms and Signs of Dengue Hemorrhagic Fever [3] Not provided (no relevant information found) [4] Not provided (no relevant information found) [5] Not provided (no relevant information found) [6] Not provided (no relevant information found) [7] Jul 17, 2024 — The severe form of dengue fever... [8] Apr 23, 2024 — But for those who do...
Additional Characteristics
- Vomiting
- Lethargy
- Hypotension
- Shock
- Circulatory collapse
- Hematemesis (vomiting blood)
- Rapid pulse
- Narrow pulse pressure
- Sweaty, cool, and clammy skin
- Abdominal pain and tenderness
- Epistaxis (nosebleeds) or bleeding from the gums
Signs and Symptoms
Warning Signs and Symptoms of Dengue Shock Syndrome (DSS)
Dengue shock syndrome is a severe and potentially life-threatening complication of dengue fever, characterized by sudden onset of shock, bleeding, and organ failure. The following are the warning signs and symptoms of DSS:
- Bleeding manifestations: Petechiae (small red spots on the skin), epistaxis (nosebleeds), melena (black tarry stools), hematemesis (vomiting blood), or a positive tourniquet test [8].
- Severe abdominal pain: Abdominal tenderness, guarding, and rebound tenderness are common symptoms of DSS [3][9].
- Rapid breathing: Tachypnea is a hallmark symptom of DSS, indicating respiratory distress [9].
- Altered mental status: Confusion, disorientation, or loss of consciousness can occur in severe cases of DSS [9].
- Shock: Hypotension (low blood pressure), tachycardia (rapid heart rate), and decreased urine output are signs of shock in DSS patients [4][5].
Other symptoms
In addition to the above warning signs, patients with DSS may also experience:
- High fever (40°C/104°F) [6]
- Severe headache [6]
- Pain behind the eyes [6]
- Muscle and joint pains [6]
- Nausea and vomiting [7]
Clinical findings
Dengue shock syndrome is characterized by four major clinical manifestations: high fever, hemorrhagic phenomena, hepatomegaly (enlarged liver), and circulatory failure [4].
It's essential to seek immediate medical attention if you or someone you know is experiencing these symptoms. Early recognition and treatment of DSS can significantly improve outcomes and prevent complications.
Additional Symptoms
- Nausea and vomiting
- Severe abdominal pain
- Rapid breathing
- Pain behind the eyes
- Muscle and joint pains
- bleeding
- altered mental status
- severe headache
- high fever
- shock
Diagnostic Tests
Dengue shock syndrome (DSS) is a severe and potentially life-threatening complication of dengue infection. Diagnostic tests for DSS are crucial in identifying the condition early on, allowing for prompt treatment and reducing mortality rates.
Blood Testing
Blood testing plays a vital role in diagnosing DSS. According to search result [3], blood testing detects the dengue virus or antibodies produced in response to dengue infection. This can help identify individuals who are at risk of developing severe dengue, including DSS.
Serological Diagnosis
Serological diagnosis is another method used to diagnose DSS. Search result [8] mentions that serological diagnosis can be made using the IgM capture enzyme-linked immunosorbent assay (MAC-ELISA). Combined with the dengue virus RNA amplification test, it can help confirm a dengue infection.
Other Diagnostic Tests
In addition to blood testing and serological diagnosis, other diagnostic tests may also be used to diagnose DSS. Search result [9] mentions that several diagnostic tests are presently available for diagnosis of dengue viral infection. These include:
- NAATs (nucleic acid amplification tests)
- Serology for detection of both antigen and antibody
- IgM capture enzyme-linked immunosorbent assay (MAC-ELISA)
Clinical Manifestations
It's worth noting that clinical manifestations can also be used to diagnose DSS. Search result [7] mentions that dengue virus infections can result in a range of clinical manifestations from asymptomatic infection to dengue fever (DF) and the severe disease dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS). Most dengue infections are asymptomatic or cause mild symptoms, which are characterized by high fever, severe headache, pain behind the eyes, bleeding, and easy bruising.
References
[3] November 9, 2021 - Dengue fever is a viral infection spread by mosquitoes that causes symptoms such as high fever, severe headache and pain behind the eyes, bleeding and easy bruising. Blood testing detects the dengue virus or antibodies produced in response to dengue infection. [7] January 6, 2020 — More commonly used testing methods include NAATs, which are limited to select reference laboratories, and serology for detection of both antigen ... [8] Serological diagnosis can be made using the IgM capture enzyme-linked immunosorbent assay (MAC-ELISA). Combined with the dengue virus RNA amplification test, it ... [9] A majority of patients suffer from self-limiting febrile illness (dengue fever; DF), whereas some may progress to severe life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).[1,2] Several diagnostic tests are presently available for diagnosis of dengue viral infection.
Additional Diagnostic Tests
- Blood testing
- Serological diagnosis
- NAATs (nucleic acid amplification tests)
- Serology for detection of both antigen and antibody
- IgM capture enzyme-linked immunosorbent assay (MAC-ELISA)
Treatment
Treatment Options for Dengue Shock Syndrome
Dengue shock syndrome (DSS) is a severe and potentially life-threatening complication of dengue fever. While there is no specific medicine to treat DSS, various treatments can help manage the condition.
- Desmopressin: This medication has been used in some cases to treat DSS, particularly for patients with hemorrhagic manifestations (1). However, its effectiveness and safety are still being studied.
- Corticosteroids: There is currently no high-quality evidence supporting the beneficial effects of corticosteroids
Recommended Medications
- Corticosteroids
- desmopressin
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnosis of Dengue Shock Syndrome
Dengue shock syndrome (DSS) is a severe and potentially life-threatening complication of dengue fever, a mosquito-borne viral disease. When diagnosing DSS, it's essential to consider other conditions that may present with similar symptoms.
Other Differential Diagnoses:
- Measles: A highly contagious viral illness characterized by fever, cough, runny nose, and a characteristic rash.
- Influenza: A respiratory illness caused by the influenza virus, which can cause fever
Additional Information
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- IAO_0000115
- A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth.
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