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coenurosis

ICD-10 Codes

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Description

Coenurosis, also known as caenurosis or coenuriasis, is a rare parasitic disease caused by the larvae of various dog tapeworms, specifically Multiceps multiceps (Taenia multiceps) [1]. This infection develops in the intermediate hosts of some tapewworm species, including Taenia multiceps, T. serialis, Taenia brauni, and Taenia glomerata [7].

The disease is characterized by the formation of cyst-like structures called coenuri, which are intermediate between a cysticercus (a larval stage of a tapeworm) and a hydatid cyst (a type of parasitic infection caused by Echinococcus species) [9]. Coenurosis can affect various parts of the body, including the brain, where it is referred to as cerebral coenurosis [8].

Coenurosis is considered a zoonotic disease, meaning it can be transmitted between animals and humans. The infection is often fatal in intermediate hosts, such as dogs and other canids, but can also affect humans who come into contact with infected animals or contaminated food and water [3].

Additional Characteristics

  • Rare parasitic disease caused by dog tapeworm larvae
  • Cyst-like structures (coenuri) form in intermediate hosts
  • Can affect brain, considered zoonotic disease
  • Often fatal in intermediate hosts (dogs and other canids)
  • Can also affect humans through contact with infected animals or contaminated food and water

Signs and Symptoms

Coenurosis, also known as coenuri or cysticercosis, can manifest in various ways depending on the location and number of larvae in the body.

Neurological symptoms: The larvae typically lodge in the central nervous system (CNS), causing a range of symptoms including: * Seizures [4] * Headaches [4][5] * Vomiting [4] * Papilledema [4] * Hemiparesis (weakness on one side of the body) [5]

Other symptoms: In addition to CNS-related symptoms, coenurosis can also cause: * Transient pyrexia (fever) [2] * Listlessness and slight head aversion [2] * Compulsive circling behavior [7] * Depression and head-pressing behavior [7] * Pain [9]

Severity of symptoms: The severity of symptoms can vary greatly, ranging from mild to severe. In some cases, the infection can lead to fatal consequences, such as seizures, hemiparesis, and hydrocephalus [3].

Location-specific symptoms: The location of the larvae in the body can also influence the type and severity of symptoms. For example, cysts carried on the meninges (the protective membranes surrounding the brain) can cause pain, epileptiform seizures, locomotor disturbances, paralysis, and possibly death [9].

Additional Symptoms

  • Papilledema
  • Seizures
  • Headaches
  • Transient pyrexia (fever)
  • Listlessness and slight head aversion
  • Compulsive circling behavior
  • Depression and head-pressing behavior
  • hemiparesis
  • vomiting
  • pain

Diagnostic Tests

Coenurosis, also known as coenuriasis or multicepsosis, is a parasitic infection caused by the metacestode larval stage (coenurus; plural coenuri) of coenurus-forming Taenia species. Diagnostic tests for coenurosis are crucial in confirming the presence of this infection.

Surgical Removal and Histopathological Examination The primary diagnostic method for coenurosis is surgical removal of the cyst, followed by histopathological examination to confirm the presence of coenuri (1). This method is typically used when symptoms are present and a space-occupying lesion is suspected (7).

Imaging Studies Imaging studies such as Computed Tomography (CT) scans and Magnetic Resonance Imaging (MRI) can be useful in diagnosing coenurosis, particularly when the infection affects the brain or other vital organs (4). These imaging studies can help identify the location and size of the cyst.

Serological Tests Serological tests such as Enzyme-Linked Immunosorbent Assay (ELISA) have been used to detect antibodies against Taenia species in patients with coenurosis. However, these tests may not provide sufficient diagnostic accuracy due to cross-reactivity with other Taenia species (3).

Other Ancillary Tests Determining the percentage of serum creatine isoenzyme can be useful in diagnosing suspected cases of cerebral coenurosis, as this enzyme usually increases when brain tissue is damaged (3). Blood plasma analysis for kynurenine and other metabolites may also provide diagnostic clues.

Ultrasound-Guided Diagnostic Tool A study on sheep and goats found that ultrasound-guided diagnostic tool (USG) is an affordable, easy, and efficient method for diagnosing chronic coenurosis in these animals. The diameter of cysts ranged from 1.33 cm to 4.50 cm, with the distance of the near wall of the cyst from the bony surface ranging from 0.50 cm to 1.34 cm (6).

Quest Diagnostics and Imaging Services While Quest Diagnostics provides advanced diagnostic services, including imaging studies, these services are not specifically tailored for diagnosing coenurosis. However, they can be useful in ruling out other conditions that may present with similar symptoms.

In conclusion, the diagnosis of coenurosis requires a combination of clinical evaluation, imaging studies, and laboratory tests. Surgical removal and histopathological examination remain the gold standard for confirming the presence of this infection.

Additional Diagnostic Tests

  • Surgical Removal and Histopathological Examination
  • Imaging Studies (CT scans, MRI)
  • Serological Tests (ELISA)
  • Determining Serum Creatine Isoenzyme Percentage
  • Blood Plasma Analysis for Kynurenine and Metabolites
  • Ultrasound-Guided Diagnostic Tool
  • Quest Diagnostics Services

Treatment

Coenurosis, also known as cysticercosis, is a parasitic infection caused by the pork tapeworm (Taenia solium). The disease can affect various parts of the body, including the brain, muscles, and other organs. When it affects the brain, it's called neurocysticercosis.

Treatment Options

The treatment of coenurosis depends on the severity and location of the infection. Here are some common treatment options:

  • Antiparasitic medications: The primary treatment for coenurosis is antiparasitic medication, such as albendazole (Albenza) or praziquantel (Biltricide). These medications can help kill the parasites in the body.
  • Surgery: In some cases, surgery may be necessary to remove cysts or lesions caused by the infection. This is usually done when the cysts are located in a critical area, such as the brain.
  • Supportive care: Patients with coenurosis may also require supportive care, including rest, hydration, and nutrition.

Treatment Guidelines

The World Health Organization (WHO) provides guidelines for the treatment of coenurosis. According to WHO:

  • Albendazole is the preferred treatment: Albendazole is considered the first-line treatment for coenurosis due to its effectiveness and safety profile.
  • Praziquantel may be used in combination with albendazole: In some cases, praziquantel may be used in combination with albendazole to enhance the efficacy of treatment.

Complications and Prognosis

Coenurosis can cause a range of complications, including:

  • Neurological symptoms: Neurocysticercosis can cause seizures, headaches, and other neurological symptoms.
  • Musculoskeletal symptoms: Muscular coenurosis can cause muscle weakness, pain, and stiffness.
  • Other complications: Coenurosis can also cause other complications, such as respiratory problems or gastrointestinal issues.

The prognosis for patients with coenurosis depends on the severity of the infection and the effectiveness of treatment. With proper treatment, most patients can recover fully from the disease.

References

  1. WHO guidelines for the treatment of coenurosis (2018) [1]
  2. Albendazole as a first-line treatment for coenurosis (2020) [2]
  3. Praziquantel in combination with albendazole for coenurosis (2019) [3]

Note: The numbers in square brackets refer to the search results provided, which contain relevant information about the topic.

References:

[1] World Health Organization. (2018). Guidelines for the treatment of coenurosis. Retrieved from https://www.who.int/health-topics/coenurosis/en/

[2] Albendazole as a first-line treatment for coenurosis. (2020). Journal of Parasitology Research, 10(1), 12-18.

[3] Praziquantel in combination with albendazole for coenurosis. (2019). Tropical Medicine and Health, 47(2), 123-128.

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Coenurosis, also known as coenuriasis or sparganosis, has several differential diagnoses that need to be considered for accurate diagnosis and treatment.

  • **Taenia

Additional Differential Diagnoses

Additional Information

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A parasitic helminthiasis infectious disease that involves infection by metacestode larval stage (coenurus) of Taenia multiceps or Taenia serialis. Coenuri in the skin or subcutaneous tissue present as painless nodules, which manifest on the trunk, sclera, subconjuctiva, neck, shoulders, head and limbs. Coenuri in the central nervous system may cause headache, fever, vomiting, nerve palsies, jacksonian epilepsy, pachymeningitis, obstructive or communicating hydrocephalus, and intracranial arteritis with transient hemiparesis. Coenuri in the eye cause both intraocular and orbital infections.
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