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obsolete primary Legionellaceae infectious disease
ICD-10 Codes
Description
Obsolete Primary Legionellaceae Infectious Disease
The term "obsolete primary Legionellaceae infectious disease" refers to a condition that was previously considered a distinct medical entity, but is no longer recognized as such in modern medical practice.
- According to search result [10], this condition was characterized by physical symptoms and was once considered a chronic factitious illness.
- It is worth noting that the term "obsolete" implies that this condition is no longer considered relevant or valid in contemporary medical diagnosis and treatment. [10]
In summary, the obsolete primary Legionellaceae infectious disease is a previously recognized medical condition that is no longer considered a distinct entity in modern medicine.
Citations: [10]
Additional Characteristics
- A condition previously considered a distinct medical entity
- Characterized by physical symptoms and once considered a chronic factitious illness
- No longer recognized as such in modern medical practice
Signs and Symptoms
Legionnaires' Disease: A Review of Signs and Symptoms
Legionnaires' disease, caused by the bacterium Legionella pneumophila, is a severe respiratory infection that can manifest in various ways. The signs and symptoms of this disease are crucial for early diagnosis and treatment.
Common Signs and Symptoms:
- Respiratory Illness: Acute onset of lower respiratory illness with fever or cough [13]
- Fever: High fever
Additional Symptoms
- Respiratory Illness
- fever
Diagnostic Tests
Based on the provided context, it appears that there are various diagnostic tests available for Legionnaires' disease (legionellosis), an infection caused by Legionella bacteria.
- Culture and Serology: According to search result [3], the diagnostic methods currently available for legionellosis include culture, serology, direct fluorescent antibody testing, and urinary antigen detection. However, these tests may not be as effective in detecting all serogroups of L. pneumophila, as mentioned in search result [2].
- Direct Fluorescence Antigen Detection: Search result [2] suggests that direct fluorescence antigen detection may be a more valuable test for surveillance of nosocomial legionellosis, as it can detect all serogroups of Legionella.
- Urinary Antigen Tests: Search result [4] mentions urinary antigen tests for the diagnosis of respiratory infections, including legionellosis. However, the effectiveness and specificity of these tests are not explicitly stated in this context.
- Culturing of the Organism: Search result [6] recommends culturing of the organism as a diagnostic test for legionnaires' disease, although it is noted that this method may have limitations.
It's worth noting that while these tests exist, their effectiveness and specificity may vary. Additionally, new and emerging technologies may offer improved diagnostic capabilities for legionellosis.
References: [2] PC Lück · 2002 · Cited by 27 [3] Jun 14, 2024 — The diagnostic methods currently available... [4] Urine antigen tests for the diagnosis of respiratory infections: legionellosis, histoplasmosis, pneumococcal pneumonia. [6] sive diagnostic tests for the diagnosis of legion- naires' disease should be strongly encouraged.
Additional Diagnostic Tests
- Culture and Serology
- Direct Fluorescence Antigen Detection
- Urinary Antigen Tests
- Culturing of the Organism
Treatment
Treatment Options for Legionnaires' Disease
Legionnaires' disease, caused by the Legionella bacteria, requires prompt medical attention and treatment to manage symptoms and prevent complications.
- Antibiotics: The primary treatment for legionnaires' disease involves antibiotics to combat the bacterial infection. [1]
- Levofloxacin (Levaquin): This antibiotic has been shown to be effective in treating Legionella pneumonia, making it a commonly prescribed medication. [2]
- Azithromycin and Clarithromycin: Other antibiotics may also be used to treat legionnaires' disease, particularly in combination with supportive care. [3]
Supportive Care
In addition to antibiotic treatment, patients with legionnaires' disease often require hospitalization for supportive care, which includes:
- Fluid replacement: To manage dehydration and electrolyte imbalances.
- Oxygen therapy: To support breathing and oxygenation of the body.
- Pain management: To alleviate chest pain and discomfort.
Importance of Prompt Medical Attention
It is essential to seek medical attention immediately if symptoms of legionnaires' disease are suspected. Delayed treatment can lead to severe complications, including respiratory failure and death. [4]
References:
[1] Context: 2 [2] Context: 3 [3] Context: 4 [4] Context: 5
Recommended Medications
- Antibiotics
- Azithromycin and Clarithromycin
- levofloxacin
- Levofloxacin
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnoses for Legionellosis
Legionellosis, caused by the bacterium Legionella pneumophila, can be challenging to diagnose due to its similarity in presentation with other respiratory infections. Here are some differential diagnoses that clinicians should consider:
- Sepsis secondary to Legionella pneumonia: This is a critical condition that requires immediate attention and treatment.
- Streptococcus pneumoniae infection: A common cause of community-acquired pneumonia, which can present similarly to legionellosis.
- SARS-CoV-2 infection: Although the virus that causes COVID-19 has distinct characteristics, it's essential to consider it in the differential diagnosis, especially during outbreaks.
Rare Manifestations
In addition to these common differential diagnoses, there are some rare manifestations of Legionella infections that clinicians should be aware of:
- Septic arthritis
- Peritonitis
- Myocarditis
- Pericarditis
- Native-valve and prosthetic valve endocarditis
Diagnostic Considerations
When considering the differential diagnosis for legionellosis, clinicians should also think about the following:
- Urine antigen test: This is a key diagnostic tool that can help confirm the presence of Legionella pneumophila.
- Culturing sputum, BAL, and urine samples: These tests can provide valuable information for diagnosing legionellosis.
References
- Kao et al., 2022 - Sepsis secondary to Legionella pneumonia was considered as a differential diagnosis.
- Chitasombat et al., 2018 - Primary cutaneous and subcutaneous infection caused by Legionella pneumophila is rare and challenging to diagnose.
- Eison et al., 2014 - Rare manifestations of Legionella have included septic arthritis, peritonitis, myocarditis, pericarditis, and native-valve and prosthetic valve endocarditis.
Note: The references provided are based on the search results and may not be an exhaustive list.
Additional Differential Diagnoses
- Sepsis secondary to Legionella pneumonia
- Streptococcus pneumoniae infection
- SARS-CoV-2 infection
- Native-valve and prosthetic valve endocarditis
- myocarditis
- pericarditis
- peritonitis
- septic arthritis
Additional Information
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_372
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:0050319
- core#notation
- DOID:0050319
- rdf-schema#label
- obsolete primary Legionellaceae infectious disease
- owl#deprecated
- true
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/doid#gram-negative_bacterial_infectious_disease
- relatedICD
- http://example.org/icd10/T80.211
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
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