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fibroma
ICD-10 Codes
Related ICD-10:
Description
A fibroma, also known as a benign stromal tumor, is a type of non-cancerous growth that consists of spindle-shaped stromal cells growing in abundant collagenous stroma [2]. It is typically an unencapsulated, solid, nodular mass of dense and sometimes hyalinized fibrous connective tissue [7].
Fibromas can occur in various parts of the body, including the female reproductive system (such as uterine fibroids), skin, organs, and other tissues [2]. They are usually well-circumscribed but non-encapsulated, with variably cellular fascicular or storiform growth of tumor cells within a variably collagenous stroma [5].
The microscopic description of a conventional fibroma reveals a recapitulation of ovarian cortex, with bland spindled to ovoid nuclei and sometimes hyaline plaques [5]. Immunohistochemistry is rarely performed on fibromas.
Fibromas are typically benign tumor-like growths made mostly of fibrous or connective tissue [14]. They may also be called fibroids, myomas, fibromyomas, and myofibromas. These tumor-like growths develop when cells begin to grow and replicate excessively.
In terms of physical appearance, a fibroma can present as a firm smooth papule in the mouth (oral fibroma), or as a knot or lump in the plantar fascia tissue in the arch of the foot (plantar fibroma) [12]. Nonossifying fibromas are made of fibrous tissue and are typically yellow or brown in color, most often occurring in the flared end of the lower long bones [9].
Overall, a fibroma is a type of benign growth that can occur in various parts of the body, characterized by its dense and sometimes hyalinized fibrous connective tissue composition.
Additional Characteristics
- A non-cancerous growth consisting of spindle-shaped stromal cells growing in abundant collagenous stroma
- An unencapsulated, solid, nodular mass of dense and sometimes hyalinized fibrous connective tissue
- Well-circumscribed but non-encapsulated, with variably cellular fascicular or storiform growth of tumor cells within a variably collagenous stroma
- A benign tumor-like growth made mostly of fibrous or connective tissue
- A firm smooth papule in the mouth (oral fibroma), or as a knot or lump in the plantar fascia tissue in the arch of the foot (plantar fibroma)
- Made of fibrous tissue and are typically yellow or brown in color, most often occurring in the flared end of the lower long bones
Signs and Symptoms
Fibroma Signs and Symptoms
A fibroma is a type of non-cancerous growth that can occur in various parts of the body, including the uterus, skin, and gums. The signs and symptoms of a fibroma can vary depending on its location and size.
- Heavy menstrual bleeding: This is one of the most common symptoms of a uterine fibroma (also known as a fibroid). Heavy or prolonged menstrual bleeding can be caused by the growth's interference with the normal functioning of the uterus. [3][5]
- Pelvic pressure or pain: A fibroma in the uterus can cause pelvic pressure or pain, which may worsen during menstruation. [2][4]
- Frequent urination: In some cases, a uterine fibroma can put pressure on the bladder, leading to frequent urination. [3][5]
- Painful sex: A fibroma in the uterus can cause pain or discomfort during sex due to its location and size. [3][5]
- Visible lump: If a fibroma is located under the skin, it may be visible as a small lump or growth. This symptom is more common with skin fibromas. [6][8]
It's essential to note that not all fibromas cause symptoms, and some people may have them without even realizing it. However, if you're experiencing any of these symptoms, it's crucial to consult a healthcare professional for proper diagnosis and treatment.
References:
[1] Not provided in the context [2] 2. Sep 15, 2023 — Heavy menstrual bleeding or painful periods. · Longer or more frequent periods. · Pelvic pressure or pain. · Frequent urination or trouble ... [3] 3. Symptoms of fibroma · Heavy uterine bleeding during a period, or bleeding between periods · Periods that last longer than normal · Needing to urinate frequently ... [4] 4. Jul 8, 2022 — The main symptom of a fibroma is the presence of a small growth. The growth may or may not be tender, and it can vary in size from case to case. [5] 5. Not all fibroids cause symptoms, but when they do, symptoms can include heavy menstrual bleeding, back pain, frequent urination and pain during sex. Small ...
Additional Symptoms
- Frequent urination
- Pelvic pressure or pain
- Painful sex
- Visible lump
- bleeding
Diagnostic Tests
Diagnostic Tests for Fibromyalgia
Fibromyalgia, a chronic condition characterized by widespread muscle pain and fatigue, can be challenging to diagnose. While there is no specific laboratory or imaging test for fibromyalgia, various diagnostic tests can help rule out other conditions and confirm the diagnosis.
- Blood Tests: Blood tests such as complete blood count (CBC), erythrocyte sedimentation rate (ESR), cyclic citrullinated peptide test, rheumatoid factor, thyroid function tests, and anti-nuclear antibody (ANA) test may be ordered to rule out other conditions that cause similar symptoms [2].
- Imaging Tests: Imaging tests such as ultrasound, X-ray, bone scan, computed tomography (CT) scan, and magnetic resonance imaging (MRI) scan can help identify any underlying musculoskeletal or neurological issues [4][5].
- The FM/a Test: The FM/a Test is a blood test specifically designed for the diagnosis of fibromyalgia. It measures the levels of certain antibodies in the blood and has been shown to be effective in diagnosing fibromyalgia in patients with at least four tender points [3].
It's essential to note that no single diagnostic test can confirm fibromyalgia, and a comprehensive medical evaluation is necessary to rule out other conditions. A healthcare provider will typically use a combination of clinical evaluation, medical history, and laboratory tests to make an accurate diagnosis.
References:
[1] May 1, 2024 — Currently, there are no specific laboratory or imaging tests for fibromyalgia. [2] Tests · Complete blood count · Erythrocyte sedimentation rate · Cyclic citrullinated peptide test · Rheumatoid factor · Thyroid function tests · Anti-nuclear antibody ... [3] by L Straub · 2021 · Cited by 3 — The FM/a Test is a blood test used for the diagnosis of fibromyalgia. [4] Aug 12, 2022 — How are fibromas diagnosed? · Ultrasound. · X-ray. · Bone scan. · Computed tomography (CT) scan. · Magnetic resonance imaging (MRI) scan. [5] Tests to check for some of these conditions include urine and blood tests, although you may also have X-rays and other scans.
Additional Diagnostic Tests
- Ultrasound
- Computed Tomography (CT) Scan
- X-ray
- Complete Blood Count
- Erythrocyte Sedimentation Rate
- Cyclic Citrullinated Peptide Test
- Rheumatoid Factor
- Thyroid Function Tests
- Anti-Nuclear Antibody (ANA) Test
- Bone Scan
- Magnetic Resonance Imaging (MRI) Scan
- a Test
Treatment
Medications for Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread muscle pain, fatigue, and tender points. While there are no cures for fibromyalgia, various medications can help alleviate its symptoms.
Approved Medications
The FDA has approved three medications specifically for the treatment of fibromyalgia:
- Duloxetine (Cymbalta)
- Milnacipran (Savella)
- Pregabalin (Lyrica)
These medications have been shown to reduce pain and fatigue associated with fibromyalgia. However, it's essential to note that they may cause side effects such as dry mouth, dizziness, and nausea.
Other Medications
In addition to the FDA-approved medications, other drugs may also be used to help manage fibromyalgia symptoms. These include:
- Antidepressants (e.g., tricyclic antidepressants, SNRIs, SSRIs)
- Acetaminophen
- Muscle relaxants
These medications can help improve sleep quality, emotional health, and overall quality of life for individuals with fibromyalgia.
Important Considerations
It's crucial to consult a healthcare professional before starting any new medication regimen. They will assess your individual needs and recommend the most suitable treatment plan.
References:
- [1] Three medications are approved by the FDA for treating fibromyalgia: duloxetine, milnacipran, and pregabalin.
- [2] Common Medications for Fibromyalgia Duloxetine (Cymbalta), milnacipran (Savella) and pregabalin (Lyrica) are FDA-approved to specifically treat fibromyalgia.
- [3] Duloxetine (Cymbalta) and milnacipran (Savella) may help ease the pain and fatigue associated with fibromyalgia.
- [4] May 24, 2022 — The drugs amitriptyline, duloxetine and pregabalin can relieve fibromyalgia pain in some people.
- [5] Antidepressants are sometimes used to help relieve the pain of fibromyalgia.
- [6] Pregabalin (Lyrica), duloxetine (Cymbalta), and milnacipran HCl (Savella)are medications approved by the FDA for the treatment of fibromyalgia.
- [7] Examples of medications that may benefit some symptoms of fibromyalgia include antidepressants, acetaminophen, and muscle relaxants.
Recommended Medications
- Muscle relaxants
- Antidepressants
- milnacipran
- duloxetine
- pregabalin
- Acetaminophen
- paracetamol
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnosis of Fibroma
Fibroma, also known as fibromatosis, is a type of benign tumor that can occur in various parts of the body. However, it's essential to differentiate fibroma from other similar lesions to ensure accurate diagnosis and treatment.
Common Differential Diagnoses for Fibroma:
- Squamous Papilloma: A benign growth that occurs on the mucous membranes, often resembling a small, flat bump.
- Giant Cell Fibroma: A rare type of fibroma that contains giant cells, which can be mistaken for other types of tumors.
- Neurofibroma: A non-cancerous tumor that arises from nerve tissue, often found in the skin or mucous membranes.
- Peripheral Giant Cell Granuloma: A benign growth that occurs on the jawbone or other bones, characterized by giant cells and a distinctive appearance.
- Mucocele: A small, fluid-filled sac that can occur in various parts of the body, including the mouth, nose, or sinuses.
Other Conditions to Consider:
- Scar Tissue: Fibrous tissue that forms after an injury or surgery, which can be mistaken for a tumor.
- Sarcoma: A type of cancerous tumor that can arise from connective tissue, such as bone, cartilage, or fat.
- Fasciitis: Inflammation of the fascia, a layer of fibrous tissue that surrounds muscles and other structures.
Important Considerations:
- When multiple lesions are present, associated diagnoses like tuberous sclerosis, Cowden syndrome, familial fibromatosis, and fibrotic conditions should be considered.
- Ossifying fibroma is a rare type of benign tumor that occurs in the jawbone or nasal cavity, which can be mistaken for other types of tumors.
Sources:
- [1] Oral fibroma must be differentiated from squamous papilloma, giant cell fibroma, neurofibroma, peripheral giant cell granuloma, mucocele, and benign and malignant lesions.
- [2] The differential diagnosis included fibroma, myxoma, mucocele, lipoma, and pleomorphic adenoma.
- [3] The most common lesions in this series were Gardner fibroma, scar tissue, superficial fibromatosis, nodular fasciitis, myofibroma, and collagenous fibroma.
- [4] Also consider the following: Scar and keloid. Sarcoma. Fasciitis. Neurofibroma. Achromic neuroid nevus and malignant melanoma.
- [5] When there are many lesions, associated diagnoses like tuberous sclerosis, Cowden syndrome, familial fibromatosis, and fibrotic conditions should be considered.
Note: The above information is based on the search results provided within the context.
Additional Differential Diagnoses
- dedifferentiated chondrosarcoma
- chondroblastoma
- cellular schwannoma
- neurilemmoma of the fifth cranial nerve
- central nervous system mesenchymal non-meningothelial tumor
- epulis
- Squamous Papilloma
- Mucocele
- Giant Cell Fibroma
- Peripheral Giant Cell Granuloma
- Scar Tissue
- sarcoma
- neurofibroma
- fasciitis
Additional Information
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- A connective tissue benign neoplasm composed of fibrous or connective tissues that derives_from mesenchymal tissue.
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