uterine fibroid

What are Uterine Fibroids?

Uterine fibroids, also known as leiomyomas, are growths that develop in or on the uterus. They are typically not cancerous (benign) and do not become cancerous [1]. These growths can be found in women of childbearing age and are often present during pregnancy and childbirth.

Characteristics of Uterine Fibroids

• Uterine fibroids are muscular tumors that grow in the wall of the uterus [5].
• They can grow in and around the uterus, making them a common benign tumor in women of childbearing age [6].
• The cause of uterine fibroids is unknown [9].

Symptoms of Uterine Fibroids

• Symptoms can include heavy and prolonged periods, bleeding between periods, pressure in the abdomen, and pelvic pain [7].
• Abnormal uterine bleeding, such as heavy menstrual bleeding or intermenstrual bleeding, can be caused by fibroids [8].
• Bleeding can be severe enough to cause anemia.

Types of Uterine Fibroids

• Result: a benign smooth muscle neoplasm arising from the body of the uterus; it is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern [10].

Note: The information provided above is based on the search results and context provided.

Common Signs and Symptoms of Uterine Fibroids

Uterine fibroids can cause a range of symptoms, which can vary in severity from woman to woman. Here are some common signs and symptoms associated with uterine fibroids:

• Heavy or Prolonged Menstruation: Heavy menstrual bleeding or prolonged periods (lasting longer than 7 days) [1][2]
• Bleeding Between Periods: Bleeding between periods, also known as intermenstrual bleeding [3][6]
• Menstrual Clots: Heavy bleeding during the period with blood clots [3][4]
• Painful Periods: Pain or cramping during menstruation [2][5]
• Pelvic Pressure or Pain: Feeling of fullness, heaviness, or pressure in the pelvic area [7]
• Frequent Urination: Frequent urination or trouble urinating due to fibroids pressing on the bladder [1][8]

It's essential to note that not all women with uterine fibroids will experience symptoms. However, if you're experiencing any of these signs and symptoms, it's crucial to consult a healthcare provider for proper diagnosis and treatment.

References: [1] - Context result 1 [2] - Context result 4 [3] - Context result 3 [4] - Context result 8 [5] - Context result 9 [6] - Context result 6 [7] - Context result 7 [8] - Context result 8

Diagnostic Tests for Uterine Fibroids

Uterine fibroids can be diagnosed through various imaging tests and procedures. Here are some of the common diagnostic tests used to detect uterine fibroids:

• Ultrasound: A painless exam that uses sound waves to obtain a picture of the uterus. This is often the first imaging test used to diagnose uterine fibroids [1][2].
• MRI (Magnetic Resonance Imaging): An imaging test that provides more detail than an ultrasound, and can help determine the number, location, and size of the fibroids [3][4].
• Hysterosonography: A procedure that uses sound waves to produce a picture of the uterus, similar to an ultrasound [5].
• Hysterosalpingography: A test that uses X-rays to examine the shape and function of the uterus and fallopian tubes [6].
• Blood tests: While not a direct imaging test, blood tests can help diagnose uterine fibroids by detecting abnormal levels of certain hormones or proteins in the blood [4].
• Endometrial biopsy: A procedure that involves taking a sample of tissue from the lining of the uterus to check for any abnormalities, including uterine fibroids [7].

These diagnostic tests can help determine the presence and characteristics of uterine fibroids, which is essential for developing an effective treatment plan.

References:

[1] Context 1: Sep 15, 2023 — Uterine fibroids often are found by chance during a routine pelvic exam. Your doctor may feel irregular changes in the shape of your uterus, ...

[2] Context 6: Ultrasound—A painless exam that uses sound waves to obtain a picture of the uterus.

[3] Context 5: Diagnosis of uterine fibroids · Magnetic resonance imaging (MRI) – This is an imaging test that provides more detail than an ultrasound.

[4] Context 7: by MSYLD DE LA CRUZ · 2017 · Cited by 372 — Ultrasonography is the recommended initial imaging modality for diagnosis of uterine fibroids. ... Management of uterine fibroids should be ...

[5] Context 5: Diagnosis of uterine fibroids · Hysterosonography – A procedure that uses sound waves to produce a picture of the uterus.

[6] Context 4: Diagnostic tests for uterine fibroids include x-ray hysteroscopy, transvaginal ultrasound, MRI, hysterosalpingography, blood test and endometrial biopsy.

[7] Context 8: One of the main tests carried out to diagnose fibroids is an ultrasound scan. This is a painless scan that uses a probe to produce high frequency sound ...

Treatment Options for Uterine Fibroids

Uterine fibroids can be treated using various methods, including drug treatment. According to the available information [2][3], there are several medications that can help manage symptoms and reduce the size of fibroids.

• Hormone-based treatments: Medications such as oral contraceptives, hormone therapy, and GnRH agonists can help slow down or stop the growth of fibroids, reduce bleeding, and alleviate pain [4][6].
• Selective progesterone receptor modulators (SPRMs): SPRMs like ulipristal acetate, mifepristone, and letrozole have been shown to be effective in treating heavy menstrual bleeding, relieving pain, and reducing the need for a hysterectomy [5][7].
• Other medications: Levonorgestrel intrauterine system (LNG-IUS), tranexamic acid, anti-inflammatory medicines, and oral progestogen can also be used to manage symptoms and reduce fibroid size [8].

It's essential to note that the best treatment option for uterine fibroids depends on various factors, including the severity of symptoms, age, and overall health. A healthcare provider will recommend a personalized treatment plan based on individual needs.

References:

[2] Context result 3 [3] Context result 15 [4] Context result 4 [5] Context result 9 [6] Context result 6 [7] Context result 5 [8] Context result 7

Differential Diagnosis of Uterine Fibroids

Uterine fibroids, also known as leiomyomas, are benign tumors that arise from the smooth muscle layer of the uterus. When diagnosing uterine fibroids, it's essential to consider their differential diagnosis, which includes both benign and malignant conditions.

Common Symptoms

• Abnormal uterine bleeding
• Pelvic pain
• Bulk symptoms (e.g., pressure on surrounding organs)
• Back pain

These symptoms are often caused by the size and location of the fibroids, as well as their impact on surrounding tissues [4].

Differential Diagnosis

The differential diagnosis for uterine leiomyomas includes:

• Benign conditions: Adenomyosis, endometrial polyps, ovarian cysts
• Malignant conditions: Uterine leiomyosarcoma, smooth muscle tumors of uncertain malignant potential (STUMP), and rare cases of uterine lipoleiomyoma [7]

Other Conditions to Consider

• Adnexal tumors (e.g., angiolipoma, cylindroma)
• Dermal nevi
• Dermatofibroma/dermatomyofibroma
• Neuroma
• Giant cell tumor
• Glomus tumor
• Hamartoma

These conditions can present with similar symptoms and may require further evaluation to rule out a diagnosis of uterine fibroids [5].

Evaluation and Diagnosis

The evaluation of fibroids is based mainly on the patient's presenting symptoms, including abnormal menstrual bleeding, bulk symptoms, pelvic pain, or other complaints. A thorough medical history, physical examination, and imaging studies (e.g., ultrasound) are essential for accurate diagnosis [2].

References:

[1] AM Florence · 2023 · Cited by 19 [2] MSYLD DE LA CRUZ · 2017 · Cited by 372 [4] K Barjon · 2023 · Cited by 34 [5] Jun 15, 2021 [6] EA Stewart · Cited by 25 [7] Oct 20, 2024