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obsolete secondary malignant neoplasm of intra-abdominal lymph node

Description

Obsolete Code for Secondary Malignant Neoplasm of Intra-Abdominal Lymph Nodes

The code "C78.4" was previously used to describe a secondary malignant neoplasm of small intestine, which is now classified under the code "C77.2". This change reflects an update in the classification system for cancer diagnoses.

Historical Context

In the past, the code "C78.4" was used to indicate a metastatic tumor originating from the small intestine and spreading to intra-abdominal lymph nodes. However, with the introduction of new coding systems and classifications, this code has been replaced by more specific and accurate codes, such as "C77.2".

Current Classification

The current classification system for cancer diagnoses uses codes like "C77.2" to describe secondary malignant neoplasms of intra-abdominal lymph nodes. These codes provide a more detailed and accurate representation of the disease, allowing for better tracking and management of cancer cases.

References: * [1] - Code Information: Diagnosis Code: C78.4 (now obsolete) * [5] - ERROR: ERROR: ERROR (contains information on intra-abdominal metastasis) * [7] - Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes (current classification)

Additional Characteristics

  • C78.4 was previously used for secondary malignant neoplasm of small intestine, now classified under C77.2
  • Code C78.4 indicated metastatic tumor from small intestine to intra-abdominal lymph nodes
  • Current classification system uses codes like C77.2 for secondary malignant neoplasms of intra-abdominal lymph nodes

Signs and Symptoms

Common Signs and Symptoms

The signs and symptoms of secondary malignant neoplasm of intra-abdominal lymph nodes can vary widely, but some common ones include:

  • Abdominal pain [8]
  • Fevers [8]
  • Hematuria (blood in the urine) and/or hypertension [8]
  • Urinary tract infection
  • Constipation
  • Weight loss [5]

General Symptoms

In addition to these specific symptoms, general symptoms of metastasis may also include:

  • Extreme fatigue [13]
  • Night sweats [13]
  • Unexplained weight loss [13]

Other Possible Symptoms

The type and location of the primary tumor can influence the symptoms of secondary malignant neoplasm of intra-abdominal lymph nodes. Some possible symptoms depending on the type of metastasis include:

  • Abdominal pain or changes in bowel habits for colon cancer
  • Breast pain or abnormal nipple discharge for breast cancer
  • Pain or swelling in the affected area for other types of cancer

Diagnosis

A biopsy is often necessary to confirm the presence of cancer cells in a lymph node. This can involve removing one or more lymph nodes, or taking samples using needles [14].

References:

[5] - Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats.

[8] - Abdominal pain, fevers, hematuria and/or hypertension, urinary tract infection, constipation, and weight loss are the most common signs and symptoms.

[13] - General symptoms of metastasis may include: Extreme fatigue. Night sweats. Unexplained weight loss.

[14] - However, when there are only a few cancer cells in a lymph node, the only way a doctor can check for cancer is the removal of all or part of the lymph node.

Additional Symptoms

Diagnostic Tests

Diagnostic Tests for Secondary Malignant Neoplasm of Intra-abdominal Lymph Nodes

The diagnosis of secondary malignant neoplasm of intra-abdominal lymph nodes involves a combination of clinical evaluation, imaging tests, and biopsy. Here are some diagnostic tests that may be used:

  • Imaging Tests: Computed Tomography (CT) scans or Magnetic Resonance Imaging (MRI) scans can help identify enlarged lymph nodes in the abdomen. These tests can also provide information on the extent of disease spread [10].
  • Biopsy: A biopsy involves removing a sample of tissue from the affected lymph node for examination under a microscope. This is often necessary to confirm the diagnosis and determine the type of cancer [15].
  • Blood Tests: Blood tests may be used to check for abnormal levels of certain substances in the blood, which can indicate the presence of cancer.
  • Lymph Node Dissection: In some cases, a lymph node dissection may be performed to remove multiple lymph nodes for examination.

Other Diagnostic Methods

In addition to these diagnostic tests, other methods may also be used to diagnose secondary malignant neoplasm of intra-abdominal lymph nodes. These include:

  • Cytologic Assessment: This involves examining cells from the affected lymph node under a microscope.
  • Tumor Biopsy: A biopsy of the tumor itself can provide information on the type and extent of cancer.

References

[10] Suspiciously enlarged lymph nodes are accurately depicted with CT, which is the primary staging modality for most abdominal tumors, assessment of abdominal lymph nodes in patients with extra-abdominal primary tumors (e.g., malignant melanoma, breast cancer), and systemic disease (e.g., Hodgkin disease).

[15] Obtaining adequate tissue specimens is an essential step in the diagnosis and treatment of patients with lymphoma. In patients without peripheral lymphadenopathy, intra-abdominal lymph node sampling or hepatic biopsies are necessary to confirm the diagnosis and define the histological type of lymphoma.

Note: The above information is based on the search results provided and may not be an exhaustive list of diagnostic tests for secondary malignant neoplasm of intra-abdominal lymph nodes.

Treatment

Based on the provided context, it appears that there are limited treatment options for secondary malignant neoplasm of intra-abdominal lymph nodes.

Current Treatment Options

  • Chemotherapy: While not specifically mentioned in the context, chemotherapy is a common treatment option for various types of cancer, including those affecting the lymphatic system. However, its effectiveness may vary depending on the specific type and stage of cancer (6).
  • Chemoradiotherapy or radiotherapy: In patients with advanced disease and regional LNM, chemoradiotherapy or radiotherapy can offer benefits both in the form of adjuvant treatment (9).

Specific Treatment Options for Intra-Abdominal Lymph Nodes

  • Intraperitoneal cisplatin: This treatment option has been explored as an adjuvant therapy in patients with gastric cancer who had undergone surgery (8).
  • Injection of drugs into upstream lymph nodes: A study by Kodama et al. (2016) suggested that injecting drugs into an upstream lymph node, either the sentinel lymph node or another upstream lymph node, can be effective in treating metastatic lymph nodes (4 and 5).

Important Considerations

  • The prognosis and treatment of a patient with malignant disease depend on the tumor stage, which is determined by the size of the primary tumor, the presence of metastases, and possible metastatic lymph node involvement (10).
  • Treatment options may vary depending on the specific type and location of cancer, as well as the extent of disease.

In summary, while there are some treatment options available for secondary malignant neoplasm of intra-abdominal lymph nodes, more research is needed to determine their effectiveness and optimal use.

Recommended Medications

  • Chemotherapy
  • Chemoradiotherapy or radiotherapy
  • Injection of drugs into upstream lymph nodes
  • cisplatin
  • Cisplatin

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Based on the provided context, it appears that you are looking for a list of possible differential diagnoses for an obsolete secondary malignant neoplasm of intra-abdominal lymph nodes.

Possible Differential Diagnoses:

  • Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes (C77.2) [7]
  • Malignant neoplasm of splenic flexure (C18.5) with lymph node metastasis [15]
  • Peritoneal metastasis from colorectal cancer, which may present as a distinct subset with regional disease rather than systemic disease [3]

Other Considerations:

  • The presence of metastatic disease in the primary tumor or areas of metastases, such as bone marrow, lymph nodes, or other organs (e.g., neuroblastoma cells) [9]
  • Secondary cancer in the lymph nodes, which can spread via the blood or lymph fluid [10]

Important Notes:

  • The prognosis and treatment of a patient with malignant disease depend on the tumor stage, which is determined by the size of the primary tumor, the presence of metastases, and possible metastatic lymph node involvement [12]
  • Solid tumors comprise a leading cause of mortality among patients with multiple primary cancers, including second malignant neoplasms (SMNs) [13]

References:

[1] - Cited by 6 [3] - Cited by 21 [7] - Cited by 2 [9] - Cited by 4 [10] - Cited by 1 [12] - Cited by 16 [13] - Cited by 57

Additional Differential Diagnoses

  • Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes (C77.2)
  • Malignant neoplasm of splenic flexure (C18.5) with lymph node metastasis
  • Peritoneal metastasis from colorectal cancer

Additional Information

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