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placenta cancer

ICD-10 Codes

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Description

Based on the search results, here's a description of placenta cancer:

Placenta cancer, also known as choriocarcinoma or gestational trophoblastic disease (GTD), is a rare and aggressive form of cancer that occurs in the uterus or ovaries. It typically starts in the tissue that would normally become the placenta during pregnancy.

The abnormal cells start to grow and multiply rapidly, leading to the formation of tumors. These tumors can spread to other parts of the body, including the lungs, brain, and other organs.

Symptoms of placenta cancer may include:

  • Irregular bleeding from the vagina
  • Coughing up blood or shortness of breath (if the tumor has spread to the lungs)
  • Headaches, dizziness, or blackouts (if the tumor has spread to the brain)

Placenta cancer can develop after any pregnancy, but it's more likely to occur after a molar pregnancy. It's essential to seek medical attention if you experience any unusual symptoms or

Additional Characteristics

  • Irregular bleeding from the vagina
  • Coughing up blood or shortness of breath
  • Headaches, dizziness, or blackouts

Signs and Symptoms

Common Signs and Symptoms of Placenta Cancer (Choriocarcinoma)

Placenta cancer, also known as choriocarcinoma, is a rare type of cancer that develops in the uterus. The symptoms can vary depending on the stage and location of the cancer. Here are some common signs and symptoms:

  • Abnormal Vaginal Bleeding: This is one of the most common symptoms of placenta cancer. Women may experience irregular or heavy bleeding, which can be red or watery brown in color [1][2].
  • Severe Nausea and Vomiting: Some women may experience severe nausea and vomiting, especially during the first three months after a molar pregnancy or recent delivery [3].
  • Grape-like Cysts: In some cases, women may pass grapelike cysts through their vagina [4].
  • Pain or Pressure in the Abdomen: If the cancer has spread to the abdomen, women may experience pain or pressure in this area [5].
  • Coughing of Blood (Hemoptysis): If the

Additional Symptoms

Diagnostic Tests

Diagnostic Tests for Placenta Cancer

Placenta cancer, also known as gestational trophoblastic disease (GTD), can be diagnosed using various tests and procedures. Here are some of the diagnostic tests used to detect placenta cancer:

  • Blood tests: Blood tests measure the amount of certain substances in your body to help diagnose GTD. For example, a pregnant person with GTD may have higher human chorionic gonadotropin (hCG) hormone levels than a pregnant person without GTD [3].
  • Urine pregnancy test: A urine pregnancy test is used to confirm pregnancy and detect any abnormalities in the placenta [5].
  • Ultrasound scan: An ultrasound scan can help identify any abnormalities in the uterus or ovaries, which may indicate GTD [8].
  • Chest x-ray: A chest x-ray may be done to check if the cancer has spread to other tissues or organs [6].
  • CT scan: A CT scan can provide more detailed images of the body and help identify any abnormalities in the uterus, ovaries, or other organs [6].
  • MRI scan: An MRI scan can also provide detailed images of the body and help identify any abnormalities in the uterus, ovaries, or other organs [6].
  • Blood and urine tests: Blood and urine tests may be done to measure hCG levels and detect any abnormalities in the placenta [10].

Other Diagnostic Tests

In addition to these tests, a pelvic exam may find an enlarged uterus and ovaries, which can indicate GTD [4][9]. A pathologic examination of the placenta can also provide insight into likely causes of antepartum and intrapartum events, diagnoses with urgent clinical relevance, prognostic information for mother and infant, support for practice evaluation and improvement, and insight into advancing the sciences of obstetrics and neonatology [12].

Non-Invasive Prenatal Testing (NIPT)

NIPT uses placental cell-free DNA in maternal blood to screen for fetal aneuploidy. However, it is not a diagnostic test for GTD or placenta cancer [13].

NanoVelcro Chip

The NanoVelcro Chip contains nanowires coated with antibodies that capture trophoblasts from the placenta found in the mother's circulation. This chip was originally created to detect tumor cells in the blood of cancer patients, but it has been adapted for use in detecting placenta accreta spectrum (PAS) disorder [14].

Placental Pathology Report

A placental pathology report can provide valuable information about maternal and fetal conditions during pregnancy. However, the abilities to perform a preliminary gross examination and interpret a placental pathology report are variable among obstetricians [15].

Additional Diagnostic Tests

  • Blood tests
  • CT scan
  • Blood and urine tests
  • MRI scan
  • Ultrasound scan
  • Chest x-ray
  • Pelvic exam
  • Urine pregnancy test
  • Placental pathology report

Treatment

Treatment Options for Placenta Cancer

Placenta cancer, also known as gestational trophoblastic disease (GTD), can be treated with various medications depending on the severity and stage of the condition.

  • Chemotherapy: This is usually the main treatment for GTD. Chemotherapy uses drugs to eliminate cancer cells. It may be taken by pill or administered intravenously. [8][9]
  • Targeted therapies: These are specifically designed to target the molecular and immunological drivers of tumorigenesis, revolutionizing oncological treatment in recent years. [13]

Specific Drugs Used

Some specific drugs used to treat placenta cancer include:

  • Doxorubicin: This is a chemotherapy medication that has been shown to be effective in treating GTD. It works by killing cancer cells or stopping their growth. [14]
  • Other chemotherapeutic agents: These may also be used to treat GTD, depending on the individual case and the stage of the disease.

Importance of Early Detection

Early detection and treatment are crucial for successful management of placenta cancer. If you suspect that you have this condition, it is essential to consult a healthcare professional promptly.

Note: The information provided above is based on the search results and may not be comprehensive or up-to-date. It is always best to consult a qualified healthcare professional for personalized advice and treatment.

Recommended Medications

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnoses for Placenta Cancer

Placenta cancer, also known as gestational trophoblastic disease (GTD), is a rare condition that can be challenging to diagnose. Here are some differential diagnoses that may be considered:

  • Hydatidiform mole: A type of GTD characterized by abnormal trophoblastic proliferation and villous edema.
  • Choriocarcinoma: A rare and aggressive form of cancer that occurs in the uterus or ovaries, often associated with GTD.
  • Placental site trophoblastic tumor (PSTT): A type of GTN that arises from the placenta and can be mistaken for a hydropic abortion.
  • Epithelioid trophoblastic tumor (ETT): A rare and aggressive form of GTN that can mimic other types of tumors.
  • Cesarean scar pregnancy: A condition where a pregnancy develops in the scar tissue from a previous C-section, which can be mistaken for a placental malignancy.
  • Placenta increta: A condition where the placenta grows too deeply into the uterine wall, which can be confused with GTD.
  • Vasa previa: A condition where fetal blood vessels are exposed and at risk of rupture, which can be mistaken for a placental malignancy.

Key Features to Consider

When considering differential diagnoses for placenta cancer, it's essential to look out for the following features:

  • Human chorionic gonadotropin (hCG) levels: Elevated hCG levels are often associated with GTD and can help differentiate it from other conditions.
  • Ultrasound findings: Specific ultrasound features, such as villous edema or cistern formation, can be indicative of a hydatidiform mole or other types of GTD.
  • Clinical symptoms: Symptoms like vaginal bleeding, abdominal pain, or fetal distress can be associated with various differential diagnoses.

References

[3] [4] [6] [8] [10] [12]

Note: The numbers in square brackets refer to the corresponding context points.

Additional Information

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.