Doxorubicin
CHEBI:CHEBI_28748
Chemical Information
- Molecular Formula
- C27H29NO11
- Molecular Mass
- 543.51930
- Charge
- 0
- SMILES
- COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
- InChI
- InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
- InChIKey
- AOJJSUZBOXZQNB-TZSSRYMLSA-N
Alternative Names
- (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
- (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
- (8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
- 14-hydroxydaunomycin
- 14-hydroxydaunorubicine
- Adriamycin
- doxorubicin
- Doxorubicin
- DOXORUBICIN
- doxorubicine
- doxorubicinum
Treatment Applications
-
rhabdomyosarcomaView Disease →
DOID:3247
-
alveolar rhabdomyosarcomaView Disease →
DOID:4051
-
mixed type rhabdomyosarcomaView Disease →
DOID:4065
Drug Classification
-
deoxy hexosideView Class →
CHEBI:35315
-
p-quinonesView Class →
CHEBI:25830
-
primary alpha-hydroxy ketoneView Class →
CHEBI:139590
-
tertiary alpha-hydroxy ketoneView Class →
CHEBI:139592
-
aminoglycosideView Class →
CHEBI:47779
-
anthracycline antibioticView Class →
CHEBI:49322
-
tetracenequinonesView Class →
CHEBI:51286
-
t164967
-
t165300
-
t165469
-
t166162
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:28748
- DRON_00010000
- 3639
- oboInOwl#hasDbXref
- PDBeChem:DM2
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- listing_expiration_date
- 20241231
- route
- INTRAVITREAL
- spl_id
- 2ad7c99b-8cea-4e22-826f-9e49c90605b6
- package_ndc
- 0069-4205-05
- marketing_start_date
- 20130205
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- INJECTABLE, LIPOSOMAL
- labeler_name
- GlaxoSmithKline Manufacturing SpA
- application_number
- ANDA215178
- product_ndc
- 16714-742
- core#notation
- CHEBI:28748
- active_ingredient_name
- DOXORUBICIN HYDROCHLORIDE
- active_ingredient_strength
- 600 g/600g
- pharm_class
- Anthracyclines [CS]
- unii
- 82F2G7BL4E
- spl_set_id
- 33ddfdb1-b4bc-464d-a186-49c4b156279f
- upc
- 0370710153014
- rxcui
- 1799310
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 3639
- brand_name
- Doxorubicin Hydrochloride Liposome
- brand_name_base
- Doxorubicin Hydrochloride Liposome
- oboInOwl#hasDbXref
- PDBeChem:DM2
- oboInOwl#hasAlternativeId
- CHEBI:42031
- oboInOwl#id
- CHEBI:28748
- generic_name
- Doxorubicin Hydrochloride Liposome
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723854
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_76971
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_32600
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_64816
- package_description
- 1 VIAL, SINGLE-DOSE in 1 CARTON (0069-4205-05) / 5 mL in 1 VIAL, SINGLE-DOSE
- package_marketing_start_date
- 12-SEP-96
- manufacturer_name
- Zydus Pharmaceuticals USA Inc.
- owl#annotatedSource
- t166316
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112627
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect14563
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_64816
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_47898
- has_treatment
- http://purl.obolibrary.org/obo/DOID_4310
- owl#someValuesFrom
- t2990934