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Doxorubicin

CHEBI:CHEBI_28748

Chemical Information

Molecular Formula
C27H29NO11
Molecular Mass
543.51930
Charge
0
SMILES
COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InChI
InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
InChIKey
AOJJSUZBOXZQNB-TZSSRYMLSA-N

Alternative Names

  • (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
  • (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
  • (8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • 14-hydroxydaunomycin
  • 14-hydroxydaunorubicine
  • Adriamycin
  • doxorubicin
  • Doxorubicin
  • DOXORUBICIN
  • doxorubicine
  • doxorubicinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:28748
DRON_00010000
3639
oboInOwl#hasDbXref
PDBeChem:DM2

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVITREAL
spl_id
2ad7c99b-8cea-4e22-826f-9e49c90605b6
package_ndc
0069-4205-05
marketing_start_date
20130205
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTABLE, LIPOSOMAL
labeler_name
GlaxoSmithKline Manufacturing SpA
application_number
ANDA215178
product_ndc
16714-742
core#notation
CHEBI:28748
active_ingredient_name
DOXORUBICIN HYDROCHLORIDE
active_ingredient_strength
600 g/600g
pharm_class
Anthracyclines [CS]
unii
82F2G7BL4E
spl_set_id
33ddfdb1-b4bc-464d-a186-49c4b156279f
upc
0370710153014
rxcui
1799310
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3639
brand_name
Doxorubicin Hydrochloride Liposome
brand_name_base
Doxorubicin Hydrochloride Liposome
oboInOwl#hasDbXref
PDBeChem:DM2
oboInOwl#hasAlternativeId
CHEBI:42031
oboInOwl#id
CHEBI:28748
generic_name
Doxorubicin Hydrochloride Liposome
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76971
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_32600
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64816
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (0069-4205-05) / 5 mL in 1 VIAL, SINGLE-DOSE
package_marketing_start_date
12-SEP-96
manufacturer_name
Zydus Pharmaceuticals USA Inc.
owl#annotatedSource
t166316
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112627
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect14563
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_64816
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_47898
has_treatment
http://purl.obolibrary.org/obo/DOID_4310
owl#someValuesFrom
t2990934