obsolete vulvar soft tissue tumor

Based on the provided context, it appears that there are several types of vulvar soft tissue tumors mentioned, but none specifically describe an "obsolete" vulvar soft tissue tumor.

However, I can provide information on some rare and outdated terms related to vulvar soft tissue tumors:

• Pseudosarcomatous fibroepithelial stromal polyp: This is a benign polypoid growth that occurs in the vagina, vulva, or cervix. It is strongly tied to hormonal stimulation and often occurs during pregnancy (see [15] for more information).
• Cellular angiofibroma: This is a rare benign soft tissue tumor that primarily occurs in the subcutaneous tissue of the vulva (see [5], [9], and [10] for more information).

It's worth noting that these terms may not be considered "obsolete" in the classical sense, but rather they are less commonly used or recognized in modern medical literature.

If you could provide more context or clarify what you mean by "obsolete vulvar soft tissue tumor," I'd be happy to try and assist further.

Based on the provided context, it appears that there are various signs and symptoms associated with vulvar soft tissue tumors, which may be considered obsolete in modern medical terminology.

Common presenting symptoms:

• Vaginal bleeding [7]
• A palpable vaginal mass [7]
• Polypoid-nodular lesions with ulceration [7]

Other possible symptoms:

• Itching or pruritus [3, 13]
• Tenderness or pain in the vulvar area [3, 13]
• Vaginal discharge [2]
• Lower abdominal and pelvic pain [2]

Physical examination findings:

• Whole vulvar swelling [1, 4]
• Non-tender masses on bilateral labium majus without a protruding lump [1, 4]
• Skin changes, including color changes, patches of white skin, or flakiness/thickening of the skin in the affected area [12, 13]

Important notes:

• Vulvar cancer is more common in older adults and can occur at any age [11].
• The appearance of vulvar cancer can vary depending on the type, but it often presents as a lump or sore on the vulva that may cause itching [11].

Please note that these symptoms and findings are based on the provided context and may not be comprehensive or up-to-date. If you have any specific questions or concerns about vulvar soft tissue tumors or related topics, I'll do my best to provide more information.

Diagnostic Tests for Obsolete Vulvar Soft Tissue Tumors

Vulvar soft tissue tumors are rare and can be challenging to diagnose. However, with the advancement in medical technology, various diagnostic tests have been developed to aid in the diagnosis of these tumors.

• Biopsy: A biopsy is a procedure where a small sample of tissue is removed from the affected area for examination under a microscope. This is the most definitive way to diagnose vulvar soft tissue tumors (10).
• Imaging Studies: Imaging studies such as MRI and CT scans can be used to assess the size, location, and extent of the tumor (13). However, these tests are not always necessary for diagnosis.
• Histopathologic Exam: A histopathologic exam is a detailed examination of the tissue sample under a microscope. This test can help identify the type of tumor and its behavior (9).

Other Diagnostic Tests

In addition to biopsy and imaging studies, other diagnostic tests may be used to aid in the diagnosis of vulvar soft tissue tumors.

• Colposcopy: A colposcopy is a procedure where a special magnifying device is used to closely inspect the affected area. This test can help identify any abnormalities or lesions (8).
• Blood Tests: Blood tests such as CA 125 may be used to assess for ovarian cancer-associated antigens, which can be related to vulvar soft tissue tumors (3).

Importance of Accurate Diagnosis

Accurate diagnosis is crucial in the management and treatment of vulvar soft tissue tumors. A misdiagnosis or delayed diagnosis can lead to inappropriate treatment and poor outcomes.

References:

[1] - [15] are citations from the provided context, used to support the information presented above.

Based on the provided context, it appears that there are various treatment options available for vulvar cancer, including drug treatments.

Chemotherapy

Chemotherapy is a type of cancer treatment that uses drugs to stop the growth of cancer cells. It can be used in combination with other treatments such as surgery and radiation therapy. According to search result [8], chemotherapy is the only kind of systemic medication used to treat vulvar cancer, primarily used in the later stages of the disease.

Imiquimod Cream

Imiquimod cream (Aldara or Zyclara) is an immunotherapy medication that can be used to treat vulvar cancer. It works by stimulating the immune system to fight cancer cells. As per search result [6], imiquimod cream is a common treatment option for vulvar cancer.

Chemotherapy Regimens

For metastatic vulvar cancer, chemotherapy regimens are similar to those used for metastatic cervical cancer. Combinations of chemotherapy and other treatments may be used to manage the disease. According to search result [7], chemotherapy regimens for metastatic vulvar cancer involve a combination of drugs that can help control the growth of cancer cells.

Treatment Options

The treatment plan for vulvar cancer depends on its type, stage, age, and overall health of the patient. Surgery is typically a component of the treatment plan, while chemotherapy and radiation therapy may be recommended in certain situations. As per search result [14], the stage of the cancer is the most important factor in choosing the right treatment.

Cancer Drugs

There are various cancer drugs approved by the FDA for use in vulvar cancer. These include generic names and brand names, which can be found on NCI's Cancer Drug Information summaries. According to search result [11], this list may not be exhaustive, as there may be other drugs used in vulvar cancer that are not listed here.

In summary, drug treatment options for vulvar cancer include chemotherapy, imiquimod cream, and chemotherapy regimens for metastatic disease. The choice of treatment depends on the stage, type, and overall health of the patient.

References:

[8] Chemotherapy is the only kind of systemic medication used to treat vulvar cancer. [6] Imiquimod cream (Aldara or Zyclara) is an immunotherapy medication that can be used to treat vulvar cancer. [7] Chemotherapy regimens for metastatic vulvar cancer are similar to those used for metastatic cervical cancer. [14] The stage of the cancer is the most important factor in choosing the right treatment. [11] This list may not be exhaustive, as there may be other drugs used in vulvar cancer that are not listed here.

The differential diagnosis of vulvar soft tissue tumors has evolved over time, and some previously recognized entities are now considered obsolete or rare. Here are some key points to consider:

• Fibroepithelial stromal polyp: This was once considered a distinct entity, but it is now believed to be a variant of fibroma (1). Fibromas are benign tumors that arise from the fibrous tissue of the vulva.
• Cellular angiofibroma: This tumor was previously thought to be a rare and distinct entity, but it is now considered to be a subtype of angiomyofibroblastoma (2).
• Angiomyofibroblastoma: This is a benign tumor that arises from the fibrous tissue of the vulva. It is characterized by its cellular and vascular components (3). Angiomyofibroblastomas are now considered to be the most common type of benign vulvar soft tissue tumor.
• Superficial angiomyxoma: This was once considered a distinct entity, but it is now believed to be a variant of aggressive angiomyxoma (4).
• Aggressive angiomyxoma: This is a rare and locally aggressive tumor that arises from the fibrous tissue of the vulva. It is characterized by its myxoid stroma and vascular components (5).

In terms of differential diagnosis, it's essential to consider other entities such as:

• Vulvar atrophy: This refers to the thinning and shrinkage of the vulvar skin and mucous membranes, often due to hormonal changes or aging.
• Benign tumors: Other types of benign tumors that may be considered in the differential diagnosis include hamartomas, cysts, and lipomas.
• Infectious disorders: Conditions such as Bartholin's cyst, periurethral cysts, abscesses, and hematoma should also be ruled out.
• Nonneoplastic epithelial disorders: Conditions such as lichen sclerosis and vulvar intraepithelial neoplasia (VIN) may also be considered in the differential diagnosis.

It's worth noting that the differential diagnosis of vulvar soft tissue tumors can be complex, and a thorough clinical evaluation, including imaging studies and histopathological examination, is essential to arrive at an accurate diagnosis.