imiquimod
CHEBI:CHEBI_36704
Definition
An imidazoquinoline fused [4,5-c] carrying isobutyl and amino substituents at N-1 and C-4 respectively. A prescription medication, it acts as an immune response modifier and is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.
Chemical Information
- Molecular Formula
- C14H16N4
- Molecular Mass
- 240.304
- Charge
- 0
- SMILES
- C1=2C=CC=CC2N=C(C=3N=CN(C13)CC(C)C)N
- InChI
- InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
- InChIKey
- DOUYETYNHWVLEO-UHFFFAOYSA-N
Alternative Names
- 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
- 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
- 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
- imiquimod
- Imiquimod
- imiquimodum
- R 837
Treatment Applications
-
nevoid basal cell carcinoma syndrome 1View Disease →
DOID:0070365
-
nevoid basal cell carcinoma syndrome 2View Disease →
DOID:0070366
-
squamous cell papillomaView Disease →
DOID:139
-
anal margin carcinomaView Disease →
DOID:4284
-
clear cell acanthomaView Disease →
DOID:172
-
inverted papillomaView Disease →
DOID:3179
-
vulva verrucous carcinomaView Disease →
DOID:3740
-
penis basal cell carcinomaView Disease →
DOID:4277
-
scrotum basal cell carcinomaView Disease →
DOID:4278
-
basosquamous carcinomaView Disease →
DOID:5063
-
anal squamous cell carcinomaView Disease →
DOID:5525
-
penis verrucous carcinomaView Disease →
DOID:5908
-
penis basaloid carcinomaView Disease →
DOID:7047
-
anus basaloid carcinomaView Disease →
DOID:7174
-
vulvar keratoacanthomaView Disease →
DOID:7408
-
squamous papillomatosisView Disease →
DOID:7532
-
cheek mucosa cancerView Disease →
DOID:8702
-
lethal midline granulomaView Disease →
DOID:9072
Drug Classification
-
imidazoquinolineView Class →
CHEBI:38776
-
t203763
-
t203963
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 59943
- oboInOwl#hasDbXref
- Wikipedia:Imiquimod
- core#notation
- CHEBI:36704
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 59943
- oboInOwl#hasDbXref
- Wikipedia:Imiquimod
- oboInOwl#id
- CHEBI:36704
- generic_name
- IMIQUIMOD
- brand_name
- Aldara
- brand_name_base
- Aldara
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- CREAM
- labeler_name
- SOLARA ACTIVE PHARMA SCIENCES LIMITED
- marketing_start_date
- 20060906
- product_ndc
- 62147-0087
- application_number
- ANDA205971
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36710
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- listing_expiration_date
- 20241231
- route
- TOPICAL
- package_marketing_start_date
- 30-JAN-17
- spl_id
- 92da2f82-b134-40ba-96e5-34ea8f4519ed
- package_ndc
- 62147-0087-0
- package_description
- 25 kg in 1 DRUM (62147-0087-0)
- has_treatment
- http://purl.obolibrary.org/obo/DOID_3450
- core#notation
- CHEBI:36704
- rxcui
- 967021
- active_ingredient_strength
- 12.5 mg/.25g
- manufacturer_name
- Oceanside Pharmacueticals
- active_ingredient_name
- IMIQUIMOD
- unii
- P1QW714R7M
- spl_set_id
- 9f2cbefd-f295-47e2-8a9e-3e7c5812c963
- nui
- N0000000157
- pharm_class_pe
- Increased Cytokine Production [PE]
- pharm_class
- Interferon Inducers [MoA]
- pharm_class_moa
- Interferon Inducers [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113522
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect22195
- owl#annotatedSource
- t204269
- owl#someValuesFrom
- t559728