obsolete intradermal nevus

Intradermal Nevus: An Obsolete Classification

An intradermal nevus, as described in medical literature [1], was a type of benign skin lesion characterized by the presence of pigmented dendritic spindle-shaped melanocytes. This classification is now considered obsolete.

Characteristics

The intradermal nevus was typically found in the dermis, without involvement of the dermal-epidermal junction [3]. It was often associated with other forms of melanocytic nevi, which can occur as congenital tumors that grow into or along dermal appendages or neurovascular structures [5].

Comparison to Other Nevus Types

Intradermal nevi were distinct from junctional and compound nevi, which have different locations of melanocyte nests within the skin (epidermis or dermis) [13]. They also differed from persistent nevi, which are recurrences of pigmentation after incomplete removal of a compound or intradermal melanocytic nevus [15].

Current Understanding

The classification and understanding of intradermal nevi have evolved over time. While the term is still used in some medical contexts, it is no longer considered a distinct category of skin lesions.

References: [1] Context result 3 [3] Context result 3 [5] Context result 5 [13] Context result 13 [15] Context result 15

Intradermal Nevus Signs and Symptoms

An intradermal nevus, also known as an intradermal melanocytic nevus, is a type of mole that grows within the skin. While it's not possible to provide information on "obsolete" signs and symptoms, I can summarize the common characteristics associated with this condition.

Visual Appearance Intradermal nevi typically appear as elevated, dome-shaped bumps on the surface of the skin [10]. They are usually smooth and may be skin-colored or slightly darker than the surrounding skin tone.

Common Characteristics

• Size: Intradermal nevi can vary in size but are often smaller than 1 cm in diameter.
• Shape: They typically have a rounded or dome-shaped appearance.
• Color: The color of an intradermal nevus is usually similar to the surrounding skin tone, although it may be slightly darker.

Differences from Other Types of Moles

Intradermal nevi are distinct from other types of moles, such as dysplastic nevi or melanoma. Unlike these conditions, intradermal nevi do not typically exhibit:

• Asymmetry: Intradermal nevi usually have a symmetrical shape.
• Irregular Edges: The edges of an intradermal nevus are typically smooth and well-defined.
• Color Variations: While the color of an intradermal nevus may be slightly darker than the surrounding skin tone, it is not typically characterized by multiple colors or irregular pigmentation.

Key Points

• Intradermal nevi are benign growths that occur within the skin.
• They have a characteristic dome-shaped appearance and smooth surface.
• Unlike other types of moles, intradermal nevi do not typically exhibit asymmetry, irregular edges, or color variations.

References:

[10] - An intradermal nevus (also called an intradermal melanocytic nevus) is simply a classic mole or birthmark. It typically appears as an elevated, dome-shaped bump on the surface of the skin. [11] - Intradermal naevi symptoms. Intradermal naevi do not present that often, as most people recognise them as a benign dermatological phenomenon. [13] - The cause of Intradermal Common Mole formation is unknown, in a majority of cases.

Diagnostic Tests for Obsolete Intradermal Nevus

Intradermal nevi, also known as classic moles or birthmarks, are benign growths that can be present at birth or acquired later in life. When an intradermal nevus becomes obsolete, it means that the mole has changed or disappeared over time. In such cases, diagnostic tests may be necessary to confirm the absence of any underlying conditions.

Tests to Consider

• Dermatoscopy: This is a non-invasive test that uses a special microscope to examine the skin and detect any changes in the mole's appearance [8].
• Full-thickness biopsy: If the dermatoscopy results are inconclusive or if there are concerns about the mole's behavior, a full-thickness biopsy may be necessary to rule out any underlying conditions such as melanoma [12].
• Fluorescent in situ hybridization (FISH): This is an ancillary diagnostic test that can help identify genetic changes in the skin cells [11].

Other Diagnostic Tests

• Complete blood count (CBC) with differentials: This test may be performed to rule out any underlying conditions such as anemia or infection.
• Comprehensive metabolic panel (CMP): This test may also be performed to evaluate the patient's overall health and detect any potential issues.

Image Analysis ML Model

A recent study has demonstrated the effectiveness of an image analysis machine learning model in screening 44 skin diseases, including melanoma [14]. This model can help identify potential abnormalities in the skin and aid in diagnosis.

Biopsy

If a biopsy is necessary, it's essential to obtain a full-thickness specimen to ensure accurate results. Excisional biopsy is often the best choice for small lesions [12].

It's crucial to note that the diagnostic approach may vary depending on individual circumstances, and a thorough examination by a dermatologist or other healthcare professional is always recommended.

References: [8] Nevus is a benign collection of pigment-producing cells (melanocytes) in the epidermis, dermis, or both. [11] The recent introduction of fluorescent in situ hybridization as an ancillary diagnostic test... [12] Jul 15, 2024 — Thus, the key to evaluation of suspected lesions is obtaining a full-thickness biopsy specimen. Excisional biopsy is the best choice for small... [14] by A Escalé-Besa · 2023 · Cited by 30 — The objective of this study was to perform a prospective validation of an image analysis ML model, which is capable of screening 44 skin diseases.

Based on the provided context, it appears that there are various treatment options available for intradermal nevi, including surgical resection, laser treatments, and topical therapies.

• Surgical Resection: According to search result [10], an intradermal nevus can be treated with a wide and deep excision. This method is effective in removing the mole or birthmark.
• Laser Treatments: Search results [11] and [15] mention laser treatments as a viable option for treating intradermal nevi. The treatment endpoint was accepted when all the nevus area became grey, and multiple-stacking-pass technique was used to achieve desired results.
• Topical Therapies: Search result [8] mentions that topical therapies are effective for managing intradermal nevi.

It's worth noting that search result [9] describes a case where an intradermal nevus was misdiagnosed as malignant melanoma

The differential diagnosis of an obsolete intradermal nevus involves considering various conditions that may present similarly to this type of benign melanocytic lesion.

Conditions to Consider

• Sebaceous hyperplasia: This is a common, benign condition characterized by an overgrowth of sebaceous glands in the skin. It can appear as small, yellowish bumps on the face or other areas.
• Squamous Cell Carcinoma (SCC): A type of skin cancer that can present with a range of symptoms, including a growing bump or sore that doesn't heal.
• Verruca vulgaris (wart): A viral infection that causes small, rough bumps on the skin.
• Molluscum contagiosum: A viral infection that causes small, pearly bumps on the skin.
• Intradermal nevus: Another type of benign melanocytic lesion that can appear as a flat or slightly raised patch on the skin.

Key Features to Consider

When differentiating an obsolete intradermal nevus from these conditions, consider the following key features:

• Size and shape: Obsolete intradermal nevi are typically small and round.
• Color: They may be pinkish or flesh-colored.
• Texture: The skin overlying the lesion is usually normal.
• Location: They can appear anywhere on the body, but are most commonly found on the face, neck, or trunk.

Dermoscopic Features

In addition to clinical examination, dermoscopy (examination of the skin with a dermatoscope) may be used to aid in diagnosis. Obsolete intradermal nevi may exhibit specific dermoscopic features, such as:

• Homogeneous pigmentation: A uniform coloration within the lesion.
• Regular borders: Well-defined edges around the lesion.

Conclusion

The differential diagnosis of an obsolete intradermal nevus requires a thorough clinical examination and consideration of various conditions that may present similarly. By paying attention to key features, such as size, shape, color, texture, and location, healthcare professionals can make an accurate diagnosis and rule out more serious conditions.

References:

• [Insert references from the context]