serous surface papilloma

Serous Surface Papilloma: A Rare Benign Ovarian Tumor

A serous surface papilloma is a rare benign variant of serous ovarian tumor, characterized by small papillary projections on the ovarian surface. This type of tumor is usually non-invasive and consists of club-like projections of fibromatous stroma lined by epithelium.

Key Features:

• Small papillary projections on the ovarian surface
• Club-like projections of fibromatous stroma lined by epithelium
• Non-invasive, with no invasion into the ovarian tissue
• Rare benign variant of serous ovarian tumor

Prevalence and Age Range: Serous surface papillomas are extremely rare and usually occur in adults, with a wide age range varying from 40 to 60 years. They can be bilateral in around 20% of cases.

Imaging Features: Different imaging features may aid in the classification of serous surface papillary tumors. However, further research is needed to establish specific diagnostic criteria for this rare condition.

Classification: Serous surface papillomas are classified as benign adenomas, borderline tumors, and malignant carcinomas based on their histological characteristics and clinical behavior.

References:

• [5] Serous surface papilloma is a rare benign variant of serous ovarian tumor.
• [8] Superficial papilloma of the ovary is a rare benign ovarian finding, which was first described back in 1895.
• [11] BENIGN SEROUS NEOPLASM: SEROUS CYSTADENOMA, ADENOFIBROMA, AND SURFACE PAPILLOMA.
• [12] Serous surface papillomas are exophytic surface lesions composed of club-like projections of fibromatous stroma lined by epithelium.

Serous surface papillomas are rare tumors that occur on the surface of the ovaries or other organs with a serous lining, such as the fallopian tubes or peritoneum.

Common symptoms:

• Asymptomatic in many cases [1]
• Abdominal pain or discomfort [2]
• Pelvic mass or lump sensation [3]

Other possible signs and symptoms:

• Vaginal bleeding or discharge
• Bloating or swelling of the abdomen
• Nausea or vomiting (in some cases)

It's worth noting that serous surface papillomas are often discovered incidentally during imaging studies for unrelated reasons, such as a pelvic ultrasound or CT scan. In many cases, these tumors may not cause any noticeable symptoms until they have grown significantly in size.

References:

[1] Dec 23, 2022 - Generally asymptomatic [3] Dec 23, 2022 - Symptoms related to an ovarian mass [2] Mar 5, 2024 - But some papillomas cause breast changes.

Serous surface papilloma, also known as serous surface papillary carcinoma of the ovary, can be challenging to diagnose. However, several diagnostic tests and imaging modalities can help in its detection.

• Imaging evaluation: Imaging studies such as ultrasound or MRI are often performed first to evaluate the extent of the disease. These tests can help identify any abnormalities in the ovaries or surrounding tissues [1].
• Computed Tomography (CT): CT scans may be used to stage the cancer, which is essential for determining the best course of treatment [4].
• Blood investigation: Blood tests can help confirm the diagnosis by measuring levels of certain tumor markers, such as CA-125, CEA, beta hCG, AFP, CA19-9, and LDH [9].

It's worth noting that serous surface papilloma is a rare condition, and its diagnosis may require a combination of these tests and imaging modalities.

References:

[1] by SB Park · 2018 · Cited by 19 — As the primary imaging modality for gynecological disease, ultrasound was useful for diagnosing ovarian SSPBTs, as was MRI. On ultrasound, ovarian SSPBTs ...

[4] May 8, 2024 — Imaging evaluation may be performed preferably with ultrasound or MRI, with CT usually reserved for staging purposes.

[9] Blood investigation includes CA-125 level for screening and further CEA, beta hCG levels, AFP, CA19-9, LDH level to confirm diagnosis.

Based on the provided context, it appears that there are limited treatment options available for serous surface papilloma.

• According to search result [3], ovarian serous surface papillary borderline tumors (SSPBTs) have been retrospectively evaluated, but no specific drug treatment is mentioned.
• Search result [9] mentions detection of HPV 16 DNA in a papillary lesion on the right ovary of a pregnant woman, but this does not provide information on drug treatment for serous surface papilloma.

However, it's worth noting that some treatments are available for related conditions such as cervical cancer and uterine serous carcinoma. For example:

• Search result [4] mentions bevacizumab as a treatment that has been shown to shrink or slow the growth of advanced epithelial ovarian cancers.
• Search result [5] discusses the combination of pembrolizumab and lenvatinib as a promising targeted treatment strategy for women with uterine serous carcinoma.

It's essential to consult a medical professional for personalized advice on treating serous surface papilloma, as this condition may require a tailored approach.

Based on the context provided, here are some potential differential diagnoses for serous surface papilloma:

1. Serous cystadenoma: A benign ovarian tumor that can have a similar appearance to serous surface papilloma.
2. Low-grade serous carcinoma: A type of ovarian cancer that can exhibit low-grade nuclei and micropapillary architecture, similar to serous surface papilloma.
3. High-grade serous carcinoma: A more aggressive form of ovarian cancer that can also present with a papillary or micropapillary growth pattern.
4. Serous borderline tumor (SBT): A type of ovarian tumor that is considered to be of low malignant potential, but can have a similar appearance to serous surface papilloma.
5. Papillary squamous cell carcinoma: A rare type of skin cancer that can present with a papillary growth pattern, which might be confused with serous surface papilloma.

It's worth noting that the differential diagnosis for serous surface papilloma may also include other benign or malignant conditions, depending on the specific clinical and histopathological features of the case.