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endometriosis
ICD-10 Codes
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Description
What is Endometriosis?
Endometriosis is a condition in which cells similar to the lining of the uterus, or endometrium, grow outside the uterus. This can cause a range of symptoms, including painful and heavy periods, pelvic pain, and infertility.
- Causes: The exact cause of endometriosis is still unknown, but it is believed to be related to hormonal changes during menstruation.
- Symptoms:
- Painful and heavy periods
- Pelvic pain and cramping
- Infertility and difficulty getting pregnant
- Bowel or urinary symptoms (in some cases)
- Prevalence: Endometriosis affects up to 10% of women between the ages of 15 and 49, although it is estimated that only a small percentage of these cases are actually diagnosed.
Key Points
- Endometriosis is a condition in which endometrial tissue grows outside the uterus [1].
- The main symptom of endometriosis is pain in the abdomen (belly area) [3].
- Endometriosis can cause severe period pain, heavy periods, and infertility [9].
References
[1] Aug 30, 2024 - Context result 1 [2] Context result 2 [3] Mar 24, 2021 - Context result 3 [4] Context result 4 [5] Context result 5 [6] Dec 12, 2023 - Context result 6 [7] Feb 22, 2021 - Context result 7 [8] Jan 23, 2023 - Context result 8 [9] Context result 9
Additional Characteristics
- Infertility
- Endometrial tissue grows outside the uterus
- Pain in the abdomen (belly area)
- Severe period pain
- Heavy periods
Signs and Symptoms
Common Signs and Symptoms of Endometriosis
Endometriosis is a chronic condition that affects millions of women worldwide, causing significant discomfort and impacting daily life. The symptoms can vary from woman to woman, but there are some common signs and symptoms that are often associated with endometriosis.
- Pelvic Pain: This is one of the most common symptoms of endometriosis, affecting up to 90% of women with the condition [1]. Pelvic pain can be intense or mild, and may worsen just before and during menstruation.
- Heavy or Irregular Menstrual Bleeding: Many women with endometriosis experience heavy or irregular periods, which can lead to fatigue, low energy, and other symptoms [2].
- Painful Urination or Bowel Movements: Some women may experience pain while urinating or having bowel movements due to the presence of endometrial implants in these areas [3].
- Fatigue or Low Energy: Endometriosis can cause fatigue, low energy, and a general feeling of being unwell, which can impact daily life and relationships [4].
- Bloating or Nausea: Some women may experience bloating, nausea, and other gastrointestinal symptoms due to endometriosis [5].
Other Common Symptoms
In addition to the above symptoms, some women with endometriosis may also experience:
- Chronic Pelvic Pain: This is a persistent pain in the lower abdomen that can last for several days or weeks.
- Heavy Bleeding Between Periods: Some women may experience heavy bleeding between periods due to endometrial implants.
- Trouble Getting Pregnant: Endometriosis can cause infertility and make it difficult to get pregnant.
References
[1] Context 1: Pelvic pain is a common symptom of endometriosis, affecting up to 90% of women with the condition.
[2] Context 2: Heavy or irregular menstrual bleeding is a common symptom of endometriosis, causing fatigue and low energy in many women.
[3] Context 3: Painful urination or bowel movements can occur due to endometrial implants in these areas.
[4] Context 7: Fatigue, nausea, diarrhea, constipation, migraines, and bloating are some non-specific symptoms that can be caused by endometriosis.
[5] Context 8: Bloating and nausea are common symptoms of endometriosis, affecting many women.
Additional Symptoms
- Pelvic Pain
- Painful Urination or Bowel Movements
- Fatigue or Low Energy
- Bloating or Nausea
- Chronic Pelvic Pain
- Trouble Getting Pregnant
- bleeding
Diagnostic Tests
Diagnosing Endometriosis: A Comprehensive Overview
Endometriosis, a chronic and often painful inflammatory disease, can be challenging to diagnose due to its complex nature. While there is no single test that can definitively diagnose endometriosis, various diagnostic tests and procedures can help identify the condition.
Imaging Tests
- Ultrasound: A common first-line investigation for suspected endometriosis, ultrasound uses sound waves to produce images of the body. It can help locate larger endometriosis areas, such as nodules or cysts [2].
- Magnetic Resonance Imaging (MRI): An imaging technique that uses magnets and radio waves to create detailed images of organs and other structures. MRI scans can also help diagnose endometriosis by visualizing the condition's effects on surrounding tissues [5].
Surgical Procedures
- Laparoscopy: The only definitive way to diagnose endometriosis is through laparoscopy, a minor minimally invasive surgical procedure that involves inserting a small camera (laparoscope) into the pelvis. This allows healthcare providers to visually inspect the pelvic area and confirm the presence of endometriosis [3][4].
Other Diagnostic Methods
- Pelvic Exam: A physical examination by a healthcare provider can help identify cysts or scars associated with endometriosis.
- Medical and Symptom History: Understanding an individual's medical history, symptoms, and experiences can aid in the diagnostic process.
Limitations of Current Tests
While various tests and procedures are available to diagnose endometriosis, there is currently no lab test, procedure, or imaging technique that can definitively diagnose the condition without surgery [6]. However, these methods can help identify potential signs and symptoms associated with endometriosis.
Delayed Diagnosis
Unfortunately, receiving a diagnosis of endometriosis often takes time, with many individuals experiencing a delay of between seven and nine years after the onset of symptoms [10].
References:
[1] Context result 1 [2] Context result 2 [3] Context result 3 [4] Context result 4 [5] Context result 15 [6] Context result 5 [10] Context result 10
Treatment
Medications Used to Treat Endometriosis
Endometriosis can be treated medically using various medications, which aim to manage symptoms and reduce pain. Here are some common drug treatments for endometriosis:
- Hormonal Contraceptives: These are often used as a first-line treatment for endometriosis, especially in women who experience heavy or painful periods. Hormonal contraceptives can help regulate menstrual cycles and reduce inflammation [1][2].
- Progestins: Progestin-only contraceptives, such as injectable medroxyprogesterone (Depo-Provera), may be useful in treating endometriosis by reducing estrogen levels and alleviating symptoms [3].
- Gonadotropin-releasing hormone (Gn-RH) analogs: These medications can help reduce estrogen production, which can alleviate symptoms of endometriosis. However, they are typically used for short-term treatment due to potential side effects [4][5].
- Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs like ibuprofen or naproxen can be used to manage pain and inflammation associated with endometriosis [6].
Other Medications
While there isn't a cure for endometriosis, medications like hormonal contraceptives, progestins, and Gn-RH agonists can help manage symptoms by reducing estrogen levels and alleviating pain. In some cases, surgery may be necessary to treat endometriosis.
References:
[1] Dec 12, 2022 — The medication danazol (Danocrine) helps stop your body from releasing hormones that it uses to help bring about your period and increases your ...
[2] Feb 21, 2020 — In general, the therapy contains two hormones: estrogen and progestin, a progesterone-like hormone. · Typically, a woman takes the pill for 21 ...
[3] There are at least two long-acting progestin-only contraceptive methods, which may be useful in treating endometriosis: (1) injectable medroxyprogesterone (Depo-Provera),...
[4] ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and ...
[5] Aug 30, 2024 — Nonsteroidal anti-inflammatory drugs (NSAIDs) can help ease painful menstrual cramps. NSAIDs include ibuprofen (Advil, Motrin IB, others) and ...
[6] Mar 14, 2024 — While there isn't currently a cure, medications like hormonal contraceptives, progestins, and GnRH agonists can manage symptoms by reducing ...
Recommended Medications
- Hormonal Contraceptives
- Progestins
- Gonadotropin-releasing hormone (Gn-RH) analogs
- non-steroidal anti-inflammatory drug
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnoses of Endometriosis
Endometriosis, a chronic and often painful condition, can be challenging to diagnose due to its similarity in symptoms with other conditions. Here are some differential diagnoses that should be considered when evaluating a patient with suspected endometriosis:
- Pelvic Inflammatory Disease (PID): Characterized by pelvic pain during menstruation, dysuria, and fever [6]. PID is often caused by bacterial infections and can mimic the symptoms of endometriosis.
- Uterine conditions: Such as adenomyosis or uterine fibroids, which typically cause lower abdominal pain and heavy menstrual bleeding [7].
- Pelvic adhesions: Can cause chronic pelvic pain and infertility, similar to endometriosis [1].
- Dysmenorrhea: A condition characterized by severe menstrual cramps that can be mistaken for endometriosis symptoms.
- Low back pain: Can be caused by various conditions, including musculoskeletal issues or referred pain from the pelvis.
Key Points
- Endometriosis shares symptoms with other conditions, making differential diagnosis crucial [8].
- A definitive diagnosis of endometriosis can only be made through direct visualization of ectopic endometrial lesions via laparoscopy [3].
- Other conditions that should be considered when evaluating a patient with suspected endometriosis include dysmenorrhea, pelvic adhesions, and uterine conditions [1].
References
[1] Jul 18, 2023 — Other conditions that should be considered when evaluating a patient with suspected endometriosis include dysmenorrhea, pelvic adhesions, ...
[3] by AL MOUNSEY · 2006 · Cited by 271 — The preferred method for the diagnosis of endometriosis is direct visualization of ectopic endometrial lesions (usually via laparoscopy) ...
[6] Jun 22, 2018 — Endometriosis shares symptoms, including pelvic, abdominal, and period pain, with other conditions. Learn more about other conditions with ...
[7] by M Scioscia · 2020 · Cited by 40 — Endometriosis of pancreas, kidney, and gallbladder show hypoechoic lesions that can be seen by ultrasound and they require a second evaluation ...
[8] Differential Diagnosis #1: Pelvic Inflammatory Disease (PID). Rationale. The patient's description of pelvic pain during menstruation, dysuria, ...
Additional Differential Diagnoses
- Low back pain
- Uterine conditions
- Pelvic adhesions
- Dysmenorrhea
- pelvic inflammatory disease
- peritoneal benign neoplasm
- umbilical hernia
- aromatase excess syndrome
- reproductive system disease
- colonic lymphangioma
- salpingo-oophoritis
- endosalpingiosis
- urinary bladder posterior wall cancer
- parametritis
- leiomyoma
- obsolete female genital tuberculosis
- adhesions of uterus
- appendix disease
- peritoneum cancer
- tuberculous oophoritis
- ovarian mucinous cystadenocarcinoma
- cervical cancer
- infertility
- diffuse peritoneal leiomyomatosis
- salpingitis isthmica nodosa
- pyosalpinx
Additional Information
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- A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.