infiltrating angiolipoma

Infiltrating Angiolipoma: A Rare Type of Lipoma

Infiltrating angiolipoma is a rare type of lipoma, which is a growth made up of fat and blood vessels that develops under the skin. Unlike non-infiltrating angiolipomas, infiltrating angiolipomas extend deeper into the skin, including muscles, fat, or fibrous tissue [1]. They are usually painless and can be found in various parts of the body, including the trunk, extremities, and chest wall.

Characteristics

Infiltrating angiolipomas are characterized by a non-capsulated tumor that extends into surrounding tissues [6]. They are often described as painful subcutaneous lesions, which can make them difficult to diagnose. In some cases, malignancy is suspected in the differential diagnosis, and therefore, a tissue diagnosis is needed to rule out an underlying malignancy [4].

Symptoms

Infiltrating angiolipomas usually present as painful subcutaneous lesions, which can be tender or painful on palpation [5]. They are relatively rare compared to non-infiltrating angiolipomas and can be found in various parts of the body.

Treatment

Symptomatic infiltrating angiolipoma warrants surgical excision [4]. This is because they can cause discomfort and pain, and in some cases, malignancy may be suspected. Surgical excision is usually the recommended treatment to remove the tumor and alleviate symptoms.

References

[1] Context 1: Infiltrating angiolipomas aren’t very common. They extend deeper into your skin, including muscles, fat or fibrous tissue. They’re usually painless. [2] Context 3: Angiolipoma is a rare type of lipoma — a growth made of fat and blood vessels that develops under your skin. [4] Context 4: Infiltrating chest wall angiolipoma usually presents as painful subcutaneous lesions. There are relatively rare compared to non-infiltrating angiolipomas. [5] Context 13: Infiltrating angiolipoma (IAL) is a rare lesion, and is a clinicopathological variant of angiolipoma, characterized by infiltration of the surrounding structures, particularly skeletal muscle. [6] Context 11: Infiltrating angiolipoma (IAL) is a rare lesion and is a clinicopathological variant of angiolipoma. IAL occurs most commonly in the trunk and extremities, it is rarely found in the head and neck regions and extremely rare in the oral cavity.

Infiltrating angiolipomas are a type of benign tumor that can cause various signs and symptoms, although they are relatively rare compared to noninfiltrating ones.

Common Signs and Symptoms:

• Painful subcutaneous nodules: Infiltrating angiolipomas typically manifest as painful nodules or lumps under the skin, which can be tender to touch.
• Gastrointestinal symptoms: Some cases of infiltrating angiolipoma may result in gastrointestinal symptoms such as indigestion and ileus (a condition where the intestines stop moving food through them).
• Soft tissue involvement: These tumors can penetrate deeper into soft tissues, including muscles, fat, or fibrous tissue.
• Painless growths: In some cases, infiltrating angiolipomas may be painless and grow slowly.

Other Possible Symptoms:

• **Muscle

To diagnose an infiltrating angiolipoma, various diagnostic modalities can be used, including:

• Imaging studies: Computed Tomography (CT) scans and Magnetic Resonance Imaging (MRI) are preferred to identify the nature of soft tissue lesions and their involvement with surrounding tissues [3][9].
• Biopsy: A core needle biopsy may be conducted to examine a sample of the angiolipoma under a microscope, looking for diseases, infections, or cancer such as liposarcoma [1].
• Ultrasound (US): US examination can suggest multiple body angiolipomas and help in localization [13].
• Soft-tissue roentgenograms: These can be helpful in diagnosis and localization of the tumor [14].

It's worth noting that the diagnosis and prognosis of angiolipomas are based entirely on the findings of histological evaluations, and there exist two types of angiolipomas: non-infiltrating and infiltrating angiolipoma, respectively [13].

Differential Diagnosis of Infiltrating Angiolipoma

Infiltrating angiolipoma, a rare benign soft-tissue neoplasm, can be challenging to diagnose due to its similarity in appearance and symptoms with other conditions. The differential diagnosis for infiltrating angiolipoma includes:

• Lipoma: A type of lipoma that contains fat and blood vessels, but is not as aggressive as infiltrating angiolipoma [1].
• Hemangioma: A benign tumor consisting of blood vessels, which can be similar in appearance to infiltrating angiolipoma [5].
• Kaposi sarcoma: A rare type of cancer that affects the skin and other organs, which can present with painful subcutaneous lesions [7].
• Angiosarcoma: A rare and aggressive form of cancer that affects the blood vessels, which can be considered in the differential diagnosis of infiltrating angiolipoma [7].
• Intramuscular Hemangioma: A type of hemangioma that is located within muscle tissue, which was previously referred to as infiltrating angiolipoma but is not related to the subcutaneous form [10].
• Angiomyolipoma: A rare tumor that consists of blood vessels and smooth muscle cells, which can be considered in the differential diagnosis of infiltrating angiolipoma [12].
• Infiltrating Lipoma: A type of lipoma that is aggressive and infiltrates surrounding tissue, which can be similar to infiltrating angiolipoma [10].
• Angiomyxolipoma: A rare tumor that consists of blood vessels and connective tissue, which can be considered in the differential diagnosis of infiltrating angiolipoma [12].
• Liposarcoma: A type of cancer that affects fat cells, which can be considered in the differential diagnosis of infiltrating angiolipoma [12].

It's essential to note that a tissue diagnosis is often needed to rule out an underlying malignancy and confirm the diagnosis of infiltrating angiolipoma. Surgical excision is usually recommended for symptomatic cases.

References:

[1] Context 2 [5] Context 5 [7] Context 7 [10] Context 10 [12] Context 12