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obsolete iris vascular disorder
Description
Iris Vascular Disorder (Obs)
The term "iris vascular disorder" has been used in the past to describe a condition characterized by abnormal blood vessels on the surface of the iris. However, this term is now considered obsolete and discouraged from use in new diagnoses.
According to medical literature [6], the descriptor "[obs]" was intended to discourage the use of such terms for new diagnoses when better diagnostic terms are available. This suggests that the condition described by "iris vascular disorder" has been reclassified or renamed, and the original term is no longer considered accurate or relevant.
It's worth noting that the medical community has moved towards more precise and descriptive terminology in recent years, reflecting advances in understanding and classification of various eye conditions [6].
References:
- [6] Medical literature describing the use of "[obs]" descriptor to discourage the use of obsolete terms.
Signs and Symptoms
Based on the provided context, it appears that there are several conditions related to the iris that may be considered as obsolete or rare vascular disorders. Here are some signs and symptoms associated with these conditions:
- Intraoperative Floppy Iris Syndrome (IFIS): This condition is characterized by a sudden, severe pain with blurred vision, nausea, and vomiting, often occurring in dark environments [2]. The first sign of IFIS is increased permeability of the blood vessels at the pupillary margin as detected by fluorescein angiography or other diagnostic tests [3].
- Bilateral Acute Dilation Iris (BADI): This condition presents with an acute onset of severe photophobia and red eyes after a flu-like syndrome, pigment discharge, and blurred vision [5]. The symptoms are similar to those of IFIS.
- Ocular Ischemic Syndrome (OIS): This rare condition is associated with severe carotid artery occlusive disease leading to ocular hypoperfusion. Principal symptoms include visual loss, transient visual loss, and ischemic ocular pain [11].
- Neovascularization of the Iris (NVI): This condition is characterized by a gradual vision loss that develops over weeks to months, with around 30% of eyes having visual acuity between 20/20 and 20/50 at presentation [10]. Once NVI is present, 95% of eyes deteriorate to counting fingers vision.
It's worth noting that these conditions are relatively rare and may not be commonly encountered in modern ophthalmology practice. However, they can still cause significant morbidity if left untreated or misdiagnosed.
References:
[2] - Sudden, severe pain with blurred vision, nausea, and vomiting [2] [3] - Increased permeability of the blood vessels at the pupillary margin as detected by fluorescein angiography or other diagnostic tests [3] [5] - Acute onset of severe photophobia and red eyes after a flu-like syndrome, pigment discharge, and blurred vision [5] [10] - Gradual vision loss that develops over weeks to months, with around 30% of eyes having visual acuity between 20/20 and 20/50 at presentation [10] [11] - Principal symptoms include visual loss, transient visual loss, and ischemic ocular pain [11]
Diagnostic Tests
Based on the provided context, it appears that there are several diagnostic tests associated with an obsolete iris vascular disorder.
Historical significance: The Amsler grid testing has been in use since 1945 and can detect functional disturbances in the central and paracentral region [1]. However, this test is not specifically related to the diagnosis of iris vascular disorders.
Modern diagnostic techniques: More recent studies have focused on multimodal imaging techniques such as AS-FA, AS-OCT, and OCT-A for diagnosing eye diseases, including those affecting the iris vasculature [10]. These tests can improve accuracy and delimitation of attributes and extension in differential diagnosis with angle or iris neovascularization, melanoma, and other iris vascular tumors.
Other diagnostic methods: Fundoscopy, B-scan ultrasonography, and optical coherence tomography are also crucial for timely diagnosis to prevent complications [2]. Additionally, immunohistochemistry and electron microscopy are essential for diagnosing vascular iridic tumors [13].
Key findings: The clinical features of iris AV malformation are characteristic, but the differential diagnosis should include other iris vascular tumors and pseudotumors. Iris capillary hemangioma is a redder, more diffuse or circumscribed mass that can occur in the irides of infants who have periocular cutaneous capillary hemangioma [15].
Summary: The diagnostic tests for obsolete iris vascular disorders are largely outdated and have been replaced by modern imaging techniques such as AS-FA, AS-OCT, and OCT-A. These newer methods provide more accurate diagnoses and can help differentiate between various eye diseases.
References: [1] - Context result 1 [2] - Context result 2 [10] - Context result 10 [13] - Context result 13 [15] - Context result 15
Additional Diagnostic Tests
- Immunohistochemistry
- Electron microscopy
- B-scan ultrasonography
- Optical coherence tomography
- Fundoscopy
- Amsler grid testing
- AS-FA (Anterior Segment Fluorescence Angiography)
- AS-OCT (Anterior Segment Optical Coherence Tomography)
- OCT-A (Optical Coherence Tomography Angiography)
Treatment
Based on the provided context, it appears that there are several outdated treatments for iris vascular disorders.
Historical Treatments
- In the past, cryotherapy was utilized to suppress iris neovascularization (Context #14). However, this treatment is no longer considered effective or relevant.
- Laser photocoagulation sessions were used to treat iris vascular tufts, but in some cases, recurrent disease required more aggressive treatment (Context #11).
Current Treatment Focus
- The current focus has shifted towards anti-VEGF agents for treating ocular angiogenesis and retinal neovascular diseases (Context #2 and #7). These treatments have revolutionized management strategies.
- High-dose corticosteroid therapy followed by a slow tapering of the drug over three to six months was once considered standard treatment for VKH disease (Context #5).
Modern Treatment Approaches
- The typical treatment approach now focuses on anti-VEGF agents, which have had a significant impact on treatment strategies for ROP and other retinal neovascular diseases.
- Intraocular hemorrhage is treated with various medical and surgical interventions, but the specific treatments are not mentioned in the provided context.
Key Takeaways
- The current understanding of iris vascular disorders has shifted towards more modern and effective treatments.
- Anti-VEGF agents have become a cornerstone in treating ocular angiogenesis and retinal neovascular diseases.
- Historical treatments such as cryotherapy and laser photocoagulation are no longer considered relevant or effective.
References:
[2] Context #2 - Mar 10, 2021 [5] Context #5 - by R Bansal · 2010 · Cited by 69 [7] Context #7 - by MF Chiang · 2018 · Cited by 10 [11] Context #11 - In some patients, several laser photocoagulation sessions may be needed and the recurrent iris vascular tufts may require more aggressive treatment. [14] Context #14 - Cryotherapy is utilized to suppress iris neovascularization and neovascular ...
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Differential Diagnosis
Based on the provided context, it appears that you are looking for information on the differential diagnosis of an obsolete iris vascular disorder.
The search results suggest that there are several conditions that can be considered in the differential diagnosis of an iris vascular lesion. Some of these conditions include:
- Neovascularisation of the iris (rubeosis iridis)
- Iris hemangioma
- Iridocorneal endothelial syndrome
- Neurocristopathy
- Uveitis masquerade syndrome
It's worth noting that some of these conditions may be more relevant than others, depending on the specific characteristics of the iris vascular lesion being considered.
According to search result [2], vascular lesions of hemangioma type are generally located in the iris without extension to iridocorneal angle. However, it's essential to consider other possible causes for a vascular lesion of the iris, including conditions such as proliferative diabetic retinopathy and retinal vein occlusion.
In addition, search result [7] mentions that iris arteriovenous malformations must be differentiated from neovascularization and other diseases affecting iris vasculature in which treatment is necessary to prevent further sequelae.
It's also important to consider the age of the patient, as mentioned in search result [2], where a case of a 77-year-old male with an iris vascular lesion suggestive of racemose hemangioma is presented.
Overall, the differential diagnosis for an obsolete iris vascular disorder would likely involve considering these various conditions and ruling out other possible causes based on the specific characteristics of the lesion being considered.
References: * [2] Vascular lesions of hemangioma type are generally located in the iris without extension to iridocorneal angle. * [7] Iris arteriovenous malformations must be differentiated from neovascularization and other diseases affecting iris vasculature.
Additional Differential Diagnoses
- Iridocorneal endothelial syndrome
- Neovascularisation of the iris (rubeosis iridis)
- Iris hemangioma
- Neurocristopathy
- arteriovenous malformation
- uveitis
- proliferative diabetic retinopathy
- retinal vein occlusion
Additional Information
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_11130
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:4800
- core#notation
- DOID:4800
- rdf-schema#label
- obsolete iris vascular disorder
- owl#deprecated
- true
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
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