cervical adenoid basal carcinoma

Based on the search results, here is a summary description of cervical adenoid basal carcinoma (ABC):

Cervical adenoid basal carcinoma (ABC) is a rare type of cancer that affects the cervix. It accounts for less than 1% of all cervical cancers and is typically found in postmenopausal women.

Characteristics:

• Composed of small, basaloid cells forming nests or cords
• May be associated with high-grade squamous intraepithelial lesions (HSIL) and contain integrated human papillomavirus type 16 DNA
• Typically asymptomatic and does not cause an abnormal appearance in the cervix
• Can co-exist with invasive squamous cell carcinoma

Prognosis:

• Generally has a favorable prognosis, especially if diagnosed at an early stage
• May be associated with a higher risk of recurrence if not completely removed

It's worth noting that ABC is a rare and relatively indolent tumor, and most cases are reported in postmenopausal women. However, it's essential to consult with a healthcare professional for accurate diagnosis and treatment options.

Based on the provided context, here are some signs and symptoms associated with cervical adenoid basal carcinoma:

1. Abnormal vaginal bleeding: This can include bleeding between periods, after intercourse, or after menopause.
2. Pain during and bleeding: Some people may experience pain during sex or heavy, foul-smelling vaginal discharge.
3. Vaginal discharge: A watery or bloodstained discharge may be present.
4. Pelvic pain: Pain in the hip or pelvic region can also occur.
5. Swelling of the legs: In more advanced cases, swelling of the legs and problems urinating or having a bowel movement may be experienced.

It's essential to note that these symptoms can also be caused by other conditions, so if you're experiencing any unusual vaginal bleeding or discharge, it's crucial to consult with a healthcare professional for proper evaluation and diagnosis.

Cervical adenoid basal carcinoma (ABC) can be challenging to diagnose, but various diagnostic tests can help confirm its presence.

• Biopsy: A biopsy is a crucial diagnostic test for cervical ABC. It involves removing a small sample of tissue from the cervix and examining it under a microscope for cancer cells [4]. In some cases, the tumor may be diagnosed as an incidental finding on cervical biopsy or excision specimens obtained during the management of another condition [4].
• Imaging studies: Imaging studies such as computerized tomography (CT) scans can help identify the location and size of the tumor. However, these tests are not typically used for diagnosing ABC specifically.
• Pap test and HPV test: While the Pap test and HPV test are screening tests for cervical cancer, they may also be used to diagnose ABC in some cases [14]. An abnormal result on either test may indicate further testing is needed to confirm the presence of a cancer or pre-cancer.

It's worth noting that ABC can co-exist with other types of cervical cancers, such as invasive squamous cell carcinoma. In these cases, additional diagnostic tests and evaluations may be necessary to determine the extent of the disease [5].

References:

[4] by A Mohamed · 2024 — Therefore, this tumor is often diagnosed as an incidental finding on cervical biopsy or excision specimens obtained as part of the management of ...

[14] This will lead to further tests which can diagnose cervical cancer or pre-cancer. The Pap test and HPV test are screening tests, not diagnostic tests. They cannot tell for certain if you have cervical cancer.

[5] by B Viriyapak · 2011 · Cited by 8 — The pathologic diagnosis was adenoid basal carcinoma co-existing with invasive squamous cell carcinoma.

Treatment Options for Cervical Adenoid Basal Carcinoma

Cervical adenoid basal carcinoma (ABC) is a rare type of cancer that affects the cervix. While it's not as common as other types of cervical cancer, treatment options are available to manage and potentially cure the disease.

• Surgery: Excision or removal of the lesion is typically curative for cervical ABC (Arch Pathol Lab Med 1980; [8]). This procedure involves surgically removing the affected area to prevent further extension of the tumor.
• Targeted Therapy: Drugs like lenvatinib and sunitinib can be used to block the actions of proteins that encourage cancer growth (Drugs.com, Nov 26, 2024). These targeted therapies are often used for advanced or recurrent cases.

Other Treatment Options

While surgery and targeted therapy are primary treatment options, other factors may influence the choice of treatment. For instance:

• Age: Cervical ABC is more common in postmenopausal women (Adenoid basal carcinoma of the uterine cervix is uncommon neoplasia mostly occurring in postmenopausal women [3]).
• Stage: The stage of cervical cancer is a crucial factor in choosing treatment. However, other factors like the location of the cancer within the cervix and overall health may also impact treatment options (Cervical Adenoid Basal Carcinoma; ...).

Important Considerations

It's essential to note that:

• Early Detection: Early detection and adequate treatment can significantly improve outcomes for cervical ABC patients.
• Side Effects: Treatment options like targeted therapy may cause side effects, such as mouth sores, easy bruising, or other symptoms (Cervical Adenoid Basal Carcinoma; ...).

References

[3] Adenoid basal carcinoma of the uterine cervix is uncommon neoplasia mostly occurring in postmenopausal women. [8] We report 6 new cases of adenoid cystic carcinoma (cylindroma) of the uterine cervix (5, invasive cancer and 1, in situ cancer). [9] In its pure form, adenoid basal carcinoma does not metastasize and has an excellent prognosis · Excision is typically curative. [11] The list includes generic names and brand names. This page also lists common drug combinations used in cervical cancer.

Differential Diagnosis of Cervical Adenoid Basal Carcinoma

Cervical adenoid basal carcinoma (ABC) is a rare and distinct type of cancer that affects the cervix. When diagnosing ABC, it's essential to consider its differential diagnosis, which includes other types of cervical tumors. Here are some key points to consider:

• Adenoid Cystic Carcinoma: This is another rare type of cervical tumor that can be challenging to distinguish from ABC. Adenoid cystic carcinoma is more aggressive than ABC and has a higher potential for metastasis [8][9]. *