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infectious mononucleosis

ICD-10 Codes

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Description

Infectious Mononucleosis: A Contagious Disease

Infectious mononucleosis, also known as "mono" or the "kissing disease," is a viral infection that affects millions of people worldwide. The disease is most commonly caused by the Epstein-Barr virus (EBV), which is highly contagious and can be spread through various means.

Symptoms of Infectious Mononucleosis

The symptoms of infectious mononucleosis are quite distinctive and include:

  • Swollen lymph glands
  • Fever
  • Sore throat
  • Extreme fatigue

These symptoms can appear suddenly, often without warning, and can last for several weeks. In some cases, the disease can also cause a rash, headache, or muscle pain.

Transmission of Infectious Mononucleosis

Infectious mononucleosis is highly contagious and can be spread through:

  • Saliva (hence the nickname "kissing disease")
  • Mucus
  • Blood

The virus can survive on surfaces for several hours, making it easy to transmit from person to person.

Demographics Affected by Infectious Mononucleosis

Infectious mononucleosis typically affects adolescents and young adults, with most cases occurring between the ages of 15 and 24. However, anyone can contract the disease, regardless of age or health status.

Complications of Infectious Mononucleosis

While infectious mononucleosis is usually a self-limiting illness, it can lead to complications in some individuals, such as:

  • Sore throat that lasts for several weeks
  • Swollen lymph nodes that persist for months
  • Fatigue and weakness that last for an extended period

Treatment of Infectious Mononucleosis

There is no specific treatment for infectious mononucleosis. However, symptoms can be managed with rest, hydration, and over-the-counter medications such as acetaminophen or ibuprofen.

Prevention of Infectious Mononucleosis

While there is no vaccine available to prevent infectious mononucleosis, practicing good hygiene and avoiding close contact with someone who has the disease can help reduce the risk of transmission.

References:

  • [1] May 9, 2024 — Infectious mononucleosis is a contagious disease most commonly caused by Epstein-Barr virus (EBV). Other viruses can also cause this disease ...
  • [2] Infectious mononucleosis is a type of infection. It causes swollen lymph glands, fever, sore throat, and often extreme fatigue. It's often spread through ...
  • [3] Infectious mononucleosis (mono) is often called the kissing disease. The virus that causes mono (Epstein-Barr virus) is spread through saliva.
  • [6] Infectious mononucleosis, also known as “mono” or the “kissing disease,” is a viral infection that causes fever, sore throat, fatigue, and swollen lymph nodes.
  • [7] Infectious mononucleosis (also known as "mono" or the "kissing disease") is a fairly common viral disease that usually affects adolescents and young adults, ...
  • [9] Infectious mononucleosis is caused by Epstein-Barr virus (EBV, human herpesvirus type 4) and is characterized by fatigue, fever, pharyngitis, ...

Additional Characteristics

  • symptoms
  • treatment
  • extreme fatigue
  • fever
  • headache
  • muscle pain
  • rash
  • sore throat
  • swollen lymph glands
  • blood
  • Infectious mononucleosis
  • viral infection
  • young adults
  • complications
  • Epstein-Barr virus
  • kissing disease
  • saliva
  • mucus
  • adolescents
  • prevention

Signs and Symptoms

Infectious Mononucleosis (Mono) Signs and Symptoms

Infectious mononucleosis, commonly referred to as the "kissing disease," is a contagious infection caused by the Epstein-Barr virus (EBV). The symptoms of mono can vary from person to person, but here are some common signs and symptoms:

  • Extreme Fatigue: One of the most noticeable symptoms of mono is extreme fatigue, which can last for several weeks or even months. [1][2]
  • Fever: A fever is another common symptom of infectious mononucleosis, often accompanied by a sore throat. [3][4]
  • Sore Throat: A sore throat is a classic symptom of mono, and it's usually caused by the virus infecting the tonsils. [5][6]
  • Swollen Lymph Glands: Swollen lymph glands in the neck, armpits, and groin are also common symptoms of infectious mononucleosis. [7][8]
  • Enlarged Spleen: In some cases, the spleen may become enlarged due to mono, which can be a serious complication if not treated properly. [9][10]

Other Possible Symptoms

In addition to these common symptoms, some people with infectious mononucleosis may also experience:

  • Head and body aches
  • Rash
  • Liver inflammation

It's essential to note that the symptoms of mono can develop slowly over time, and they may not all appear at once. If you're experiencing any of these symptoms, it's crucial to consult a healthcare professional for proper diagnosis and treatment.

References: [1] Context 2: Key points about infectious mononucleosis (mono) [2] Context 5: What are the symptoms of infectious mononucleosis (mono)? [3] Context 2: Key points about infectious mononucleosis (mono) [4] Context 4: Mononucleosis (mono) is a contagious infection caused by a herpes virus called Epstein-Barr. [5] Context 5: What are the symptoms of infectious mononucleosis (mono)? [6] Context 3: Occasionally, the symptoms of infectious mononucleosis can last for 6 months or longer. [7] Context 2: Key points about infectious mononucleosis (mono) [8] Context 9: by EB Virus · Cited by 2 — Signs and symptoms [9] Context 13: Keep in mind that mono symptoms can also show up at different times over the course of the infection. [10] Context 3: Occasionally, the symptoms of infectious mononucleosis can last for 6 months or longer.

Additional Symptoms

Diagnostic Tests

Diagnostic Tests for Infectious Mononucleosis

Infectious mononucleosis, also known as mono or glandular fever, can be diagnosed through various tests that detect the presence of antibodies to the Epstein-Barr virus (EBV) in the blood. Here are some common diagnostic tests used to confirm a diagnosis of infectious mononucleosis:

  • Heterophile Antibody Test: This test looks for antibodies called heterophile antibodies, which form in the body during the mononucleosis infection [7]. A positive result indicates the presence of EBV and confirms a diagnosis of mono.
  • Serologic Tests for Antibodies against EBV: These tests detect the presence of antibodies to EBV in the blood. In 80% to 90% of cases, a positive heterophile antibody test and serologic test for antibodies against EBV are usually diagnostic [4].
  • Monospot Test: This is a rapid test that detects the presence of heterophile antibodies in the blood. It's often used as an initial screening test for mono [1].

When to Use Diagnostic Tests

While not always necessary, diagnostic tests can be useful in confirming a diagnosis of infectious mononucleosis, especially when symptoms are mild or unclear. Specific antibody tests may be needed for people who have been exposed to EBV but do not show symptoms [3]. In some cases, additional testing may be required to rule out other conditions that may present with similar symptoms.

References

[1] Context result 1 [2] Context result 2 [3] Context result 3 [4] Context result 4 [5] Context result 5 [6] Context result 6 [7] Context result 7

Additional Diagnostic Tests

  • Heterophile Antibody Test
  • Serologic Tests for Antibodies against EBV
  • Monospot Test

Treatment

Treatment Overview

Infectious mononucleosis, also known as mono or glandular fever, is a viral infection that typically affects young adults. While there's no specific therapy available to treat the condition, supportive care and medication can help alleviate symptoms.

Medications Used

  • Antipyretics and Analgesics: Over-the-counter medications like acetaminophen (Tylenol) or ibuprofen (Advil, Aleve) are commonly used to reduce fever and relieve muscle aches.
  • NSAIDs: Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen can help with pain management.
  • Antiviral Agents: Although the effectiveness of antiviral agents like acyclovir, valomaciclovir, and valacyclovir in treating acute infectious mononucleosis is uncertain, they may be prescribed in some cases.

Treatment Goals

The primary goal of treatment for infectious mononucleosis is to alleviate symptoms and support the body's recovery process. This typically involves:

  • Rest
  • Analgesics and antipyretics to manage pain and fever
  • Antiviral agents (in some cases)
  • Supportive care, such as hydration and nutrition

Important Notes

  • Antibiotics are not effective against viral infections like infectious mononucleosis.
  • There is no specific medication available to cure the condition or reduce its duration.

References:

[1] Treatment. There's no specific therapy available to treat infectious mononucleosis. Antibiotics don't work against viral infections such as mono. (Source: 1) [2] Pharmacologic therapy generally consists of supportive care with nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen. (Source: 2) [3] The effectiveness of antiviral agents in acute IM is uncertain. (Source: 4) [5] Sore throat soothers: You can gargle with salt water and use over-the-counter medications like ibuprofen (Advil) and naproxen (Aleve). Acetaminophen (Tylenol) also works. (Source: 5) [6] Treatment of patients with infectious mononucleosis generally is supportive, consisting primarily of rest, analgesics, and antipyretics. (Source: 6) [7] You may give acetaminophen (Tylenol) or ibuprofen (Motrin) for sore throat, muscle aches or fever. (Source: 7) [8] Antibiotics do not help with mono. There are no specific medications to cure mono or reduce infection length. (Source: 8) [9] Drugs used to treat Infectious Mononucleosis; Generic name: acyclovir systemic; Drug class: purine nucleosides. (Source: 9)

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Infectious Mononucleosis

Infectious mononucleosis, also known as glandular fever, is a viral infection caused by the Epstein-Barr virus (EBV). However, there are several other conditions that can present with similar symptoms and must be considered in the differential diagnosis.

Key Differential Diagnoses:

  • Streptococcal pharyngitis: This bacterial infection can cause similar symptoms to infectious mononucleosis, including fever, sore throat, and swollen lymph nodes. However, streptococcal pharyngitis typically does not cause splenomegaly (enlarged spleen) or hepatomegaly (enlarged liver) [1].
  • Acute Mumps: This viral infection can also present with fever, sore throat, and swollen lymph nodes. However, mumps is more likely to cause parotid gland swelling and is typically seen in children [2].
  • Diphtheria: This bacterial infection can cause a severe sore throat and respiratory symptoms. However, diphtheria is relatively rare in developed countries and is often associated with a characteristic membrane on the tonsils [3].
  • Herpes Simplex Virus (HSV) infection: HSV can cause oral or genital herpes, which may present with similar symptoms to infectious mononucleosis, including fever and swollen lymph nodes. However, HSV infections are typically more localized and may be accompanied by characteristic skin lesions [4].

Other Conditions:

  • Toxoplasmosis: This parasitic infection can cause a range of symptoms, including fever, sore throat, and swollen lymph nodes. However, toxoplasmosis is relatively rare in healthy individuals and is often associated with other symptoms such as headache and confusion [5].
  • Human Herpes Virus-6 (HHV-6) infection: HHV-6 can cause a range of symptoms, including fever, sore throat, and swollen lymph nodes. However, HHV-6 infections are typically more localized and may be accompanied by characteristic skin lesions [6].

References:

[1] EBELL MH. Infectious Mononucleosis: Differential Diagnosis and Distinguishing Features. (2004)

[2] Nov 11, 2022 - Differential Diagnoses

[3] Apr 21, 2021 - Diagnostic Considerations. EBV-negative Mononucleosis.

[4] Exudative pharyngitis, anterior cervical lymphadenopathy, and fever may be clinically indistinguishable from those caused by group A beta-hemolytic streptococci

[5] The main differential diagnoses of acute infectious mononucleosis are: ... Other differential diagnoses include streptococcal pharyngitis (which may co-exist), ...

[6] Aug 13, 2024 - INTRODUCTION. Infectious mononucleosis (IM) is characterized by a triad of fever, tonsillar pharyngitis, and lymphadenopathy [1].

Note: The above answer is based on the search results provided in the context block.

Additional Information

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