Discuss This Drug

Naproxen

CHEBI:CHEBI_7476

Definition

A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.

Chemical Information

Molecular Formula
C14H14O3
Molecular Mass
230.25920
Charge
0
SMILES
COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI
InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChIKey
CMWTZPSULFXXJA-VIFPVBQESA-N

Alternative Names

  • naproxen
  • naproxen
  • (+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
  • (+)-(S)-Naproxen
  • (+)-2-(6-Methoxy-2-naphthyl)propionic acid
  • (+)-2-(Methoxy-2-naphthyl)-propionic acid
  • (+)-2-(Methoxy-2-naphthyl)-propionsaeure
  • (+)-Naproxen
  • (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
  • (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
  • (S)-(+)-Naproxen
  • (S)-2-(6-Methoxy-2-naphthyl)propanoic acid
  • (S)-2-(6-Methoxy-2-naphthyl)propionic acid
  • (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
  • (S)-Naproxen
  • Naproxen
  • naproxene
  • naproxeno
  • naproxenum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7258
oboInOwl#hasDbXref
Wikipedia:Naproxen
core#notation
CHEBI:7476

Additional References

Wikipedia:Naproxen

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
55111-273
brand_name_base
Pain Reliever
oboInOwl#hasOBONamespace
chebi_ontology
generic_name
Naproxen and Esomeprazole Magnesium
brand_name
members mark naproxen sodium
DRON_00010000
7258
oboInOwl#hasDbXref
Wikipedia:Naproxen
oboInOwl#hasAlternativeId
CHEBI:603695
oboInOwl#id
CHEBI:7476
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50630
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_59527
labeler_name
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
application_number
ANDA200629
spl_id
6689b65d-827d-afee-3b22-50834dfa311a
listing_expiration_date
20241231
marketing_start_date
20070529
dosage_form
TABLET, MULTILAYER, EXTENDED RELEASE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
package_ndc
72036-145-01
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113734
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29524
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_59527
owl#someValuesFrom
t3009961
owl#annotatedSource
t283524
route
ORAL
has_treatment
http://purl.obolibrary.org/obo/DOID_90
package_description
30 TABLET in 1 BOTTLE (63187-535-30)
package_marketing_start_date
29-JUL-98
spl_set_id
fa2fe6fd-c476-dd29-e053-6294a90a9e9e
manufacturer_name
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
rxcui
1550957
unii
6V9V2RYJ8N
upc
0372789321301
active_ingredient_strength
550 mg/1
active_ingredient_name
ESOMEPRAZOLE MAGNESIUM TRIHYDRATE
nui
N0000175722
core#notation
CHEBI:7476
pharm_class
alpha-Adrenergic Agonist [EPC]
pharm_class_epc
Nonsteroidal Anti-inflammatory Drug [EPC]
pharm_class_moa
Cyclooxygenase Inhibitors [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
brand_name_suffix
Back and Muscle Pain Caplets
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class