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Cephalothin

CHEBI:CHEBI_124991

Definition

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.

Chemical Information

Molecular Formula
C16H16N2O6S2
Molecular Mass
396.43800
Charge
0
SMILES
[H][C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(O)=O)=C(COC(C)=O)CS[C@]12[H]
InChI
InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1
InChIKey
XIURVHNZVLADCM-IUODEOHRSA-N

Alternative Names

  • (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
  • 7-(2-Thienylacetamido)cephalosporanic acid
  • 7-(2'-thienylacetamido)cephalosporanic acid
  • 7-(Thiophene-2-acetamido)cephalosporin
  • 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid
  • Cefalothin
  • cefalotin
  • Cefalotin
  • cefalotina
  • cefalotine
  • cefalotinum
  • Cephalothin
  • CEPHALOTHIN
  • Cephalotin
  • CET

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2236
oboInOwl#hasDbXref
Wikipedia:Cephalothin
core#notation
CHEBI:124991

Additional References

Wikipedia:Cephalothin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2236
oboInOwl#hasDbXref
Wikipedia:Cephalothin
oboInOwl#id
CHEBI:124991
core#notation
CHEBI:124991
oboInOwl#hasAlternativeId
CHEBI:50895
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_50897
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_50897
owl#annotatedSource
t96744
owl#someValuesFrom
t481129