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voclosporin

CHEBI:CHEBI_135957

Chemical Information

Molecular Formula: C63H111N11O12
Molecular Mass: 1214.624
Charge: 0
SMILES: [C@H]([C@@H](C/C=C/C=C)C)(O)[C@@]1(N(C)C(=O)[C@](C(C)C)(N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC([C@@H](N(C([C@@](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)(C(C)C)[H])=O)C)CC(C)C)=O)[H])[H]
InChI: InChI=1S/C63H111N11O12/c1-25-27-28-29-41(15)53(76)52-57(80)66-44(26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27-28,35-48,50-53,76H,1,26,29-34H2,2-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b28-27+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1
InChIKey: BICRTLVBTLFLRD-PTWUADNWSA-N

Alternative Names

ISA 247
ISA-247
ISA247
ISATX247

Treatment Applications

obsolete chronic glomerulonephritis with lesion of membranoproliferative glomerulonephritis
DOID:10998

View Disease →
obsolete nephrotic syndrome with lesion of membranoproliferative glomerulonephritis
DOID:1183

View Disease →
cyclosporiasis
DOID:12750

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obsolete hereditary inflammatory vasculitis
DOID:14680

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Drug Classification

processed material
homodetic cyclic peptide
CHEBI:24613

View Class →

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000: 2475166
oboInOwl#hasDbXref: Drug_Central:4366
core#notation: CHEBI:135957

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect4993
owl#annotatedSource: t108500
owl#someValuesFrom: t3754200
oboInOwl#hasOBONamespace: chebi_ontology
DRON_00010000: 2475166
oboInOwl#hasDbXref: Drug_Central:4366
oboInOwl#id: CHEBI:135957
core#notation: CHEBI:135957
rxcui: 2475406
product_type: BULK INGREDIENT
marketing_category: EXPORT ONLY
listing_expiration_date: 20251231
route: ORAL
dosage_form: CAPSULE
pharm_class_moa: Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA]
pharm_class: Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA]
pharm_class_epc: Calcineurin Inhibitor Immunosuppressant [EPC]
nui: N0000190108
marketing_start_date: 20231118
package_marketing_start_date: 22-JAN-21
active_ingredient_strength: 7.9 mg/1
labeler_name: Aurinia Pharma U.S., Inc.
generic_name: Voclosporin
product_ndc: 53296-0130
spl_id: 41510e08-9441-466f-b3d4-e63384abccf6
active_ingredient_name: VOCLOSPORIN
package_ndc: 53296-0130-0
package_description: 75 kg in 1 DRUM (53296-0130-0)
brand_name: LUPKYNIS
brand_name_base: LUPKYNIS
application_number: NDA213716
manufacturer_name: Aurinia Pharma U.S., Inc.
unii: 2PN063X6B1
spl_set_id: 9f489295-1156-52c7-5fd0-5c4c52f9b813
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#2_STAR
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class