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Cefotaxime

CHEBI:CHEBI_204928

Definition

A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.

Chemical Information

Molecular Formula
C16H17N5O7S2
Molecular Mass
455.46500
Charge
0
SMILES
[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
InChI
InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1
InChIKey
GPRBEKHLDVQUJE-QSWIMTSFSA-N

Alternative Names

  • (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid
  • cefotaxima
  • cefotaxime
  • cefotaximum
  • Cephotaxime

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Cefotaxime
DRON_00010000
2186
core#notation
CHEBI:204928

Additional References

Wikipedia:Cefotaxime

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cefotaxime
DRON_00010000
2186
generic_name
Cefotaxime Sodium
brand_name
Cefotaxime
brand_name_base
Cefotaxime
oboInOwl#hasAlternativeId
CHEBI:41475
prefixIRI
CHEBI:204928
oboInOwl#id
CHEBI:204928
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
POWDER, FOR SOLUTION
route
INTRAVENOUS
marketing_start_date
20021120
labeler_name
SteriMax Inc.
product_ndc
52946-0826
application_number
ANDA065071
spl_id
724fb91b-3c71-4635-8362-a1d3cc992085
package_ndc
52946-0826-0
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_53670
core#notation
CHEBI:204928
rxcui
1656318
package_marketing_start_date
20021120
active_ingredient_strength
10 g/1
pharm_class
Cephalosporins [CS]
manufacturer_name
SteriMax Inc.
active_ingredient_name
CEFOTAXIME SODIUM
package_description
20 kg in 1 BOX (52946-0826-0)
unii
258J72S7TZ
spl_set_id
ef1a6dc6-bc3d-4f09-8f92-7ff328f56561
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040020
Contraindication
http://purl.obolibrary.org/obo/DOID_0040020
has_treatment
http://purl.obolibrary.org/obo/DOID_9159
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_53670
owl#annotatedSource
t145198
owl#someValuesFrom
t3004753