Cefoxitin
CHEBI:CHEBI_209807
Definition
A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase.
Chemical Information
- Molecular Formula
- C16H17N3O7S2
- Molecular Mass
- 427.45200
- Charge
- 0
- SMILES
- [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O
- InChI
- InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1
- InChIKey
- WZOZEZRFJCJXNZ-ZBFHGGJFSA-N
Alternative Names
- (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid
- cefoxitin
- Cefoxitin
- cefoxitina
- cefoxitine
- cefoxitinum
- ceftoxitin
- Cephoxitin
- CFX
- Rephoxitin
Drug Classification
-
cephalosporinView Class →
CHEBI:23066
-
beta-lactam antibiotic allergenView Class →
CHEBI:88225
-
semisynthetic derivativeView Class →
CHEBI:72588
-
cephamycinView Class →
CHEBI:55429
-
t144252
-
t145021
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Cefoxitin
- DRON_00010000
- 2189
- core#notation
- CHEBI:209807
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- rxcui
- 1739890
- listing_expiration_date
- 20251231
- manufacturer_name
- SAMSON MEDICAL TECHNOLOGIES LLC
- route
- INTRAVENOUS
- active_ingredient_strength
- 100 g/1
- marketing_start_date
- 20060310
- package_marketing_start_date
- 20060310
- spl_id
- fa6d5377-af57-45a8-aa38-685877c809a7
- active_ingredient_name
- CEFOXITIN SODIUM
- package_ndc
- 44567-246-25
- package_description
- 25 VIAL in 1 CARTON (44567-246-25) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL
- unii
- Q68050H03T
- spl_set_id
- 658a0dc6-6da5-44dc-94f2-1211619297f7
- upc
- 0363323341015
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Cefoxitin
- DRON_00010000
- 2189
- generic_name
- Cefoxitin Sodium
- brand_name
- Cefoxitin and Dextrose
- brand_name_base
- Cefoxitin and Dextrose
- oboInOwl#id
- CHEBI:209807
- oboInOwl#hasAlternativeId
- CHEBI:658070
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- POWDER, FOR SOLUTION
- labeler_name
- SAMSON MEDICAL TECHNOLOGIES LLC
- product_ndc
- 25021-110
- application_number
- ANDA200938
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_53655
- core#notation
- CHEBI:209807
- pharm_class
- Cephalosporins [CS]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8337
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect10861
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_53655
- owl#annotatedSource
- t145291
- owl#someValuesFrom
- t2995721