Discuss This Drug

Ceftriaxone

CHEBI:CHEBI_29007

Definition

A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups.

Chemical Information

Molecular Formula
C18H18N8O7S3
Molecular Mass
554.58000
Charge
0
SMILES
[H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
InChI
InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1
InChIKey
VAAUVRVFOQPIGI-SPQHTLEESA-N

Alternative Names

  • (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
  • ceftriaxona
  • ceftriaxone
  • ceftriaxonum
  • rocephin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Ceftriaxone
DRON_00010000
2193
core#notation
CHEBI:29007

Additional References

Wikipedia:Ceftriaxone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Ceftriaxone
DRON_00010000
2193
generic_name
Ceftriaxone Sodium Sterile Bulk
oboInOwl#hasAlternativeId
CHEBI:446214
prefixIRI
CHEBI:29007
oboInOwl#id
CHEBI:29007
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35625
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_53658
brand_name
CEFTRIAXONE AND DEXTROSE
brand_name_base
CEFTRIAXONE AND DEXTROSE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Samson Medical Technologies, LLC
dosage_form
INJECTION, POWDER, FOR SOLUTION
marketing_start_date
20050420
product_ndc
0781-3207
application_number
ANDA090057
listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
5f684b27-197e-45f0-b623-83a5fab20b0f
package_ndc
0781-3207-95
core#notation
CHEBI:29007
rxcui
1665046
active_ingredient_strength
100 g/1
pharm_class
Cephalosporins [CS]
active_ingredient_name
CEFTRIAXONE SODIUM
unii
023Z5BR09K
spl_set_id
fcf401df-bcdc-4773-a63b-9741c0f74b3d
manufacturer_name
B. Braun Medical Inc.
upc
0371205593018
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
package_marketing_start_date
20050420
package_description
10 VIAL, SINGLE-USE in 1 CARTON (0781-3207-95) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, SINGLE-USE
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040005
has_treatment
http://purl.obolibrary.org/obo/DOID_0070527
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_53658
owl#annotatedSource
t169846
owl#someValuesFrom
t3001199