Ceftriaxone
CHEBI:CHEBI_29007
Definition
A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups.
Chemical Information
- Molecular Formula
- C18H18N8O7S3
- Molecular Mass
- 554.58000
- Charge
- 0
- SMILES
- [H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
- InChI
- InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1
- InChIKey
- VAAUVRVFOQPIGI-SPQHTLEESA-N
Alternative Names
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
- ceftriaxona
- ceftriaxone
- ceftriaxonum
- rocephin
Drug Classification
-
cephalosporinView Class →
CHEBI:23066
-
1,3-thiazolesView Class →
CHEBI:38418
-
oxime O-etherView Class →
CHEBI:36816
-
1,2,4-triazinesView Class →
CHEBI:39410
-
t169074
-
t169471
-
t169834
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Ceftriaxone
- DRON_00010000
- 2193
- core#notation
- CHEBI:29007
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- brand_name
- CEFTRIAXONE AND DEXTROSE
- brand_name_base
- CEFTRIAXONE AND DEXTROSE
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- labeler_name
- Samson Medical Technologies, LLC
- dosage_form
- INJECTION, POWDER, FOR SOLUTION
- marketing_start_date
- 20050420
- product_ndc
- 0781-3207
- application_number
- ANDA090057
- generic_name
- CEFTRIAXONE
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Ceftriaxone
- DRON_00010000
- 2193
- oboInOwl#hasAlternativeId
- CHEBI:446214
- prefixIRI
- CHEBI:29007
- oboInOwl#id
- CHEBI:29007
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35625
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_53658
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- spl_id
- 5f684b27-197e-45f0-b623-83a5fab20b0f
- package_ndc
- 0781-3207-95
- manufacturer_name
- Samson Medical Technologies, LLC
- package_marketing_start_date
- 20050420
- package_description
- 10 VIAL, SINGLE-USE in 1 CARTON (0781-3207-95) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, SINGLE-USE
- core#notation
- CHEBI:29007
- rxcui
- 1665046
- active_ingredient_strength
- 100 g/1
- pharm_class
- Cephalosporins [CS]
- active_ingredient_name
- CEFTRIAXONE SODIUM
- unii
- 023Z5BR09K
- spl_set_id
- fcf401df-bcdc-4773-a63b-9741c0f74b3d
- upc
- 0371205593018
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_1003
- RO_0001022
- http://purl.obolibrary.org/obo/DOID_0040005
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_53658
- owl#annotatedSource
- t169846
- owl#someValuesFrom
- t3001199