Discuss This Drug

Fluorometholone

CHEBI:CHEBI_31625

Definition

A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Chemical Information

Molecular Formula
C22H29FO4
Molecular Mass
376.46170
Charge
0
SMILES
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]2(C)C=CC(=O)C=C12
InChI
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChIKey
FAOZLTXFLGPHNG-KNAQIMQKSA-N

Alternative Names

  • (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
  • Fluor-op
  • Fluorometholon
  • fluorometholone
  • fluorometholonum
  • fluorometolona
  • NSC 33001
  • Oxylone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:31625
DRON_00010000
4491
oboInOwl#hasDbXref
Wikipedia:Fluorometholone

Additional References

Wikipedia:Fluorometholone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:31625
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
4491
oboInOwl#hasDbXref
Wikipedia:Fluorometholone
oboInOwl#id
CHEBI:31625
generic_name
fluorometholone acetate
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Eyevance Pharmaceuticals
listing_expiration_date
20241231
dosage_form
SUSPENSION/ DROPS
marketing_start_date
19860501
product_ndc
24002-0030
spl_id
d313eddd-0906-4a03-8574-46a82b4f8883
brand_name
FML FORTE
brand_name_base
FML FORTE
application_number
NDA019216
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35472
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_34073
rxcui
1249631
manufacturer_name
Eyevance Pharmaceuticals
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
nui
N0000175450
package_marketing_start_date
07-MAR-19
route
OPHTHALMIC
active_ingredient_strength
2.5 mg/mL
active_ingredient_name
FLUOROMETHOLONE ACETATE
package_ndc
24002-0030-0
package_description
1 BAG in 1 CARTON (24002-0030-0) / 5 kg in 1 BAG
unii
9I50C3I3OK
spl_set_id
af59c420-789d-4c05-b3fc-c3f855bcac24
upc
0311980228057
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0110709
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110722
owl#annotatedSource
t180259
owl#someValuesFrom
t624776