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Nicorandil

CHEBI:CHEBI_31905

Definition

A pyrimidinecarboxamide that is nicotinamide in which one of the hydrogens attached to the carboxamide nitrogen is replaced by a 2-(nitrooxy)ethyl group. It has both nitrate-like and ATP-sensitive potassium channel activator properties, and is used for the prevention and treatment of angina pectoris.

Chemical Information

Molecular Formula
C8H9N3O4
Molecular Mass
211.17480
Charge
0
SMILES
[O-][N+](=O)OCCNC(=O)c1cccnc1
InChI
InChI=1S/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,(H,10,12)
InChIKey
LBHIOVVIQHSOQN-UHFFFAOYSA-N

Alternative Names

  • 2-[(pyridin-3-ylcarbonyl)amino]ethyl nitrate
  • 2-nicotinamidoethyl nitrate
  • Adancor
  • Ikorel
  • N-(2-hydroxyethyl)nicotinamide nitrate
  • nicorandil
  • nicorandilum
  • Perisalol
  • SG 75
  • SG-75
  • Sigmart

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
31748
oboInOwl#hasDbXref
Wikipedia:Nicorandil
core#notation
CHEBI:31905

Additional References

Wikipedia:Nicorandil

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
31748
oboInOwl#hasDbXref
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oboInOwl#id
CHEBI:31905
core#notation
CHEBI:31905
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_79085
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_17154
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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t183825
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