butoconazole

CHEBI:CHEBI_3240

Definition

A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to the nitrogen is substituted by a 4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl group. An antifungal agent, it is used as its nitrate salt in gynaecology for treatment of vulvovaginal infections caused by Candida species, particularly Candida albicans.

Chemical Information

Molecular Formula
C19H17Cl3N2S
Molecular Mass
411.77600
Charge
0
SMILES
Clc1ccc(CCC(Cn2ccnc2)Sc2c(Cl)cccc2Cl)cc1
InChI
InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5,7-8,10-11,13,16H,6,9,12H2
InChIKey
SWLMUYACZKCSHZ-UHFFFAOYSA-N

Alternative Names

  • 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazole
  • 1-{4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole
  • butoconazol
  • butoconazole
  • Butoconazole
  • butoconazolum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
19884
oboInOwl#hasDbXref
Wikipedia:Butoconazole
core#notation
CHEBI:3240

Additional References

Wikipedia:Butoconazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
19884
oboInOwl#hasDbXref
Wikipedia:Butoconazole
oboInOwl#id
CHEBI:3240
core#notation
CHEBI:3240
oboInOwl#hasAlternativeId
CHEBI:355508
rxcui
890786
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
CREAM
pharm_class
Azoles [CS]
route
VAGINAL
active_ingredient_strength
100 mg/5g
labeler_name
Padagis Israel Pharmaceuticals Ltd
marketing_start_date
20150429
package_marketing_start_date
20150429
manufacturer_name
Padagis Israel Pharmaceuticals Ltd
generic_name
Butoconazole nitrate micronized
brand_name
gynazole 1
brand_name_base
gynazole 1
product_ndc
59349-0034
application_number
ANDA200923
spl_id
f5fdcb30-d3e3-b460-e053-2995a90aebe8
active_ingredient_name
BUTOCONAZOLE NITRATE
package_ndc
59349-0034-0
package_description
1 BAG in 1 DRUM (59349-0034-0) / 1 BAG in 1 BAG / 25 kg in 1 BAG
unii
4805237NP5
spl_set_id
125d8ede-db38-4eb9-a6be-19208687f36a
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_61263
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2272
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108508
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect19592
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_61263
owl#annotatedSource
t187204
owl#someValuesFrom
t657718