cefpodoxime
CHEBI:CHEBI_3504
Definition
A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
Chemical Information
- Molecular Formula
- C15H17N5O6S2
- Molecular Mass
- 427.45500
- Charge
- 0
- SMILES
- [H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
- InChI
- InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
- InChIKey
- WYUSVOMTXWRGEK-HBWVYFAYSA-N
Alternative Names
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
- cefpodoxima
- cefpodoxime
- cefpodoximum
Treatment Applications
-
purulent acute otitis mediaView Disease →
DOID:10435
-
acute eustachian salpingitisView Disease →
DOID:10550
-
obsolete echovirus meningitisView Disease →
DOID:10910
-
chronic purulent otitis mediaView Disease →
DOID:14247
-
ethmoid sinusitisView Disease →
DOID:9507
Drug Classification
-
cephalosporinView Class →
CHEBI:23066
-
carboxylic acidView Class →
CHEBI:33575
-
t197234
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Cefpodoxime
- DRON_00010000
- 20489
- core#notation
- CHEBI:3504
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Cefpodoxime
- DRON_00010000
- 20489
- oboInOwl#id
- CHEBI:3504
- core#notation
- CHEBI:3504
- oboInOwl#hasAlternativeId
- CHEBI:606443
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113636
- has_treatment
- http://purl.obolibrary.org/obo/DOID_3488
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect21262
- owl#annotatedSource
- t197359
- owl#someValuesFrom
- t816954