cefpodoxime

CHEBI:CHEBI_3504

Definition

A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.

Chemical Information

Molecular Formula
C15H17N5O6S2
Molecular Mass
427.45500
Charge
0
SMILES
[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
InChI
InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
InChIKey
WYUSVOMTXWRGEK-HBWVYFAYSA-N

Alternative Names

  • (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
  • cefpodoxima
  • cefpodoxime
  • cefpodoximum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3504
oboInOwl#hasDbXref
Wikipedia:Cefpodoxime
DRON_00010000
20489

Additional References

Wikipedia:Cefpodoxime

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
309079
active_ingredient_strength
50 kg/50kg
package_marketing_start_date
29-MAY-04
manufacturer_name
Amici Pharmaceuticals, LLC.
active_ingredient_name
CEFPODOXIME PROXETIL
unii
2TB00A1Z7N
spl_set_id
9d6d7f50-9838-47e3-8214-53e2dbeeadea
upc
0368071361643
package_description
20 TABLET, FILM COATED in 1 BOTTLE (16714-395-01)
core#notation
CHEBI:3504
pharm_class
Cephalosporins [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20220518
spl_id
e945899a-4dca-4a06-bb52-fd503bbc6e4c
package_ndc
59651-955-37
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cefpodoxime
DRON_00010000
20489
oboInOwl#id
CHEBI:3504
oboInOwl#hasAlternativeId
CHEBI:606443
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
GRANULE, FOR SUSPENSION
labeler_name
Amici Pharmaceuticals, LLC.
generic_name
Cefpodoxime Proxetil (Process-II)
brand_name
CEFPODOXIME PROXETIL
brand_name_base
CEFPODOXIME PROXETIL
product_ndc
59651-955
application_number
ANDA065409
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113636
has_treatment
http://purl.obolibrary.org/obo/DOID_3488
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect21262
owl#annotatedSource
t197359
owl#someValuesFrom
t816954