Discuss This Drug

Ceftazidime

CHEBI:CHEBI_3508

Definition

A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.

Chemical Information

Molecular Formula
C22H22N6O7S2
Molecular Mass
546.57600
Charge
0
SMILES
[H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C(O)=O)\c1csc(N)n1)C([O-])=O
InChI
InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1
InChIKey
ORFOPKXBNMVMKC-DWVKKRMSSA-N

Alternative Names

  • (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate
  • CAZ
  • ceftazidima
  • ceftazidime
  • Ceftazidime anhydrous
  • ceftazidimum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3508
oboInOwl#hasDbXref
Wikipedia:Ceftazidime
DRON_00010000
2191

Additional References

Wikipedia:Ceftazidime

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:3508
rxcui
1659294
listing_expiration_date
20251231
route
INTRAVENOUS
pharm_class
Cephalosporins [CS]
active_ingredient_strength
1 kg/kg
package_marketing_start_date
20060405
manufacturer_name
Hospira, Inc.
active_ingredient_name
CEFTAZIDIME
marketing_start_date
20060420
spl_id
b4cff5d5-d1ec-4959-b062-e754517aab2d
package_ndc
0409-5086-11
package_description
10 VIAL, PHARMACY BULK PACKAGE in 1 CARTON (0409-5086-11) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, PHARMACY BULK PACKAGE (0409-5086-13)
unii
9M416Z9QNR
spl_set_id
1ab5ae3e-e303-4499-4c89-472d7cc1e46c
upc
0344567236107
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Ceftazidime
DRON_00010000
2191
generic_name
CEFTAZIDIME
brand_name
TAZICEF
brand_name_base
TAZICEF
prefixIRI
CHEBI:3508
oboInOwl#id
CHEBI:3508
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, POWDER, FOR SOLUTION
labeler_name
Antibioticos do Brasil Ltda
product_ndc
0409-5086
application_number
ANDA062640
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50696
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_53676
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040024
has_treatment
http://purl.obolibrary.org/obo/DOID_0070528
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_53676
owl#annotatedSource
t197446
owl#someValuesFrom
t2999409