Cephalexin

CHEBI:CHEBI_3534

Definition

A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.

Chemical Information

Molecular Formula
C16H17N3O4S
Molecular Mass
347.38900
Charge
0
SMILES
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O
InChI
InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
InChIKey
ZAIPMKNFIOOWCQ-UEKVPHQBSA-N

Alternative Names

  • (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
  • 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
  • 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid
  • Cefalexin
  • cefalexina
  • cefalexine
  • cefalexinum
  • Celexin
  • Cepastar
  • Cepexin
  • Cephacillin
  • Ceporexin
  • CEX

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Cefalexin
DRON_00010000
2231
core#notation
CHEBI:3534

Additional References

Wikipedia:Cefalexin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
dosage_form
FOR SUSPENSION
marketing_category
BULK INGREDIENT
labeler_name
Pharma-C, Inc.
marketing_start_date
20120604
application_number
ANDA218947
product_ndc
63629-7740
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cefalexin
DRON_00010000
2231
generic_name
Cephalexin Monohydrate
brand_name
CEPHALEXIN
brand_name_base
CEPHALEXIN
oboInOwl#id
CHEBI:3534
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_59392
package_description
8 CAPSULE in 1 BOTTLE (50090-3202-6)
package_ndc
68788-7796-2
listing_expiration_date
20241231
spl_id
198b8446-8758-eb8d-e063-6394a90a1a3a
route
ORAL
package_marketing_start_date
16-NOV-05
rxcui
645617
spl_set_id
09493dd3-0a90-620c-e063-6394a90a73ca
unii
OBN7UDS42Y
manufacturer_name
NuCare Pharmaceuticals, Inc.
core#notation
CHEBI:3534
has_treatment
http://purl.obolibrary.org/obo/DOID_9317
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_101385
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_59392
owl#annotatedSource
t197413
owl#someValuesFrom
t2909890
active_ingredient_strength
333 mg/1
active_ingredient_name
CEPHALEXIN
pharm_class
Cephalosporins [CS]
upc
0382804106288
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class