Cephalexin
CHEBI:CHEBI_3534
Definition
A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.
Chemical Information
- Molecular Formula
- C16H17N3O4S
- Molecular Mass
- 347.38900
- Charge
- 0
- SMILES
- [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O
- InChI
- InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
- InChIKey
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N
Alternative Names
- (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
- 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
- 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid
- Cefalexin
- cefalexina
- cefalexine
- cefalexinum
- Celexin
- Cepastar
- Cepexin
- Cephacillin
- Ceporexin
- CEX
Treatment Applications
-
Sakati-Nyhan syndromeView Disease →
DOID:0060359
Drug Classification
-
cephalosporinView Class →
CHEBI:23066
-
beta-lactam antibiotic allergenView Class →
CHEBI:88225
-
semisynthetic derivativeView Class →
CHEBI:72588
-
t197172
-
t197469
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Cefalexin
- DRON_00010000
- 2231
- core#notation
- CHEBI:3534
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Cefalexin
- DRON_00010000
- 2231
- oboInOwl#id
- CHEBI:3534
- core#notation
- CHEBI:3534
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_59392
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_9317
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_101385
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_59392
- owl#annotatedSource
- t197413
- owl#someValuesFrom
- t2909890