Discuss This Drug

Dobutamine

CHEBI:CHEBI_4670

Definition

A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.

Chemical Information

Molecular Formula
C18H23NO3
Molecular Mass
301.38010
Charge
0
SMILES
CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
InChI
InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
InChIKey
JRWZLRBJNMZMFE-UHFFFAOYSA-N

Alternative Names

  • (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
  • 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
  • 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
  • 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
  • DL-dobutamine
  • dobutamina
  • dobutamine
  • Dobutamine
  • DOBUTAMINE
  • dobutaminum
  • rac-dobutamine
  • racemic-dobutamine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3616
oboInOwl#hasDbXref
Wikipedia:Dobutamine
core#notation
CHEBI:4670

Additional References

Wikipedia:Dobutamine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3616
oboInOwl#hasDbXref
Wikipedia:Dobutamine
oboInOwl#hasAlternativeId
CHEBI:554519
oboInOwl#id
CHEBI:4670
generic_name
Dobutamine hydrochloride
brand_name
Dobutamine Hydrochloride in Dextrose
brand_name_base
Dobutamine Hydrochloride in Dextrose
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION, CONCENTRATE
labeler_name
Slate Run Pharmaceuticals
marketing_start_date
20050430
product_ndc
0338-1077
application_number
NDA020255
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35522
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:4670
rxcui
1812170
listing_expiration_date
20241231
manufacturer_name
Slate Run Pharmaceuticals
package_marketing_start_date
01-JAN-92
route
INTRAVENOUS
pharm_class
Adrenergic beta-Agonists [MoA]
active_ingredient_strength
250 mg/20mL
spl_id
2d7ff3bc-a140-4280-a2b6-2adfe4984b10
active_ingredient_name
DOBUTAMINE HYDROCHLORIDE
package_ndc
0338-1077-02
package_description
18 BAG in 1 CARTON (0338-1077-02) / 250 mL in 1 BAG
unii
0WR771DJXV
spl_set_id
6b17b98b-e06d-42ed-925f-69aa2699dead
upc
0314335171015
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http://purl.obolibrary.org/obo/DOID_3827
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https://w3id.org/def/predibionto#has_side_effect24851
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t224936
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t3055917