Discuss This Drug

Cefixime

CHEBI:CHEBI_472657

Definition

A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.

Chemical Information

Molecular Formula
C16H15N5O7S2
Molecular Mass
453.45000
Charge
0
SMILES
[H][C@]12SCC(C=C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)\c1csc(N)n1)C(O)=O
InChI
InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1
InChIKey
OKBVVJOGVLARMR-QSWIMTSFSA-N

Alternative Names

  • (-)-cefixim
  • (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid
  • cefixima
  • cefixime
  • cefiximum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:472657
oboInOwl#hasDbXref
PMID:17116681
DRON_00010000
25033

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
package_marketing_start_date
20201126
manufacturer_name
Health Department, Oklahoma State
marketing_start_date
20150424
spl_id
30690cba-b831-45c1-b799-a013d6cfc2db
package_ndc
68180-423-11
package_description
1 BLISTER PACK in 1 CARTON (68180-423-11) / 10 CAPSULE in 1 BLISTER PACK
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040030
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113689
has_treatment
http://purl.obolibrary.org/obo/DOID_2068
owl#annotatedSource
t224946
owl#someValuesFrom
t1064800
core#notation
CHEBI:472657
rxcui
1373016
active_ingredient_strength
50 kg/50kg
pharm_class
Cephalosporins [CS]
active_ingredient_name
CEFIXIME
unii
97I1C92E55
spl_set_id
6f1df975-f825-4301-87da-d7eba56a6890
upc
0368180407041
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
PMID:17116681
DRON_00010000
25033
generic_name
CEFIXIME
brand_name
Cefixime 400 mg UD
brand_name_base
Cefixime 400 mg UD
oboInOwl#hasAlternativeId
CHEBI:3487
prefixIRI
CHEBI:472657
oboInOwl#id
CHEBI:472657
product_type
BULK INGREDIENT
dosage_form
TABLET, CHEWABLE
marketing_category
BULK INGREDIENT
labeler_name
Health Department, Oklahoma State
product_ndc
68180-423
application_number
ANDA204835
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR