Cefazolin

CHEBI:CHEBI_474053

Definition

A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.

Chemical Information

Molecular Formula
C14H14N8O4S3
Molecular Mass
454.511
Charge
0
SMILES
[C@]12(N(C(=C(CS1)CSC3=NN=C(S3)C)C(=O)O)C([C@H]2NC(=O)CN4C=NN=N4)=O)[H]
InChI
InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
InChIKey
MLYYVTUWGNIJIB-BXKDBHETSA-N

Alternative Names

  • (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid
  • Cefamezin
  • cefazolin
  • cefazolina
  • cefazoline
  • cefazolinum
  • Cephamezine
  • Cephazolidin
  • Cephazolin
  • Cephazoline
  • CEZ

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Cefazolin
DRON_00010000
2180
core#notation
CHEBI:474053

Additional References

Wikipedia:Cefazolin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
labeler_name
General Injectables and Vaccines, Inc.
dosage_form
POWDER, FOR SOLUTION
marketing_start_date
20090201
application_number
ANDA209217
spl_id
77cfa8c7-af08-4ae8-80a6-1e6780a17d65
product_ndc
71872-7027
route
PARENTERAL
package_ndc
72572-056-10
package_description
10 VIAL, PHARMACY BULK PACKAGE in 1 CARTON (72572-056-10) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, PHARMACY BULK PACKAGE (72572-056-01)
rxcui
2630753
manufacturer_name
General Injectables and Vaccines, Inc.
package_marketing_start_date
02-SEP-21
unii
P380M0454Z
spl_set_id
c24e604f-16ca-4945-8e9d-277cc67a8c68
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cefazolin
DRON_00010000
2180
generic_name
Cefazolin Sodium Sterile Bulk
brand_name
Cefazolin Sodium
brand_name_base
Cefazolin Sodium
oboInOwl#hasAlternativeId
CHEBI:3482
oboInOwl#id
CHEBI:474053
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_53657
core#notation
CHEBI:474053
active_ingredient_strength
1 g/3mL
pharm_class
Cephalosporins [CS]
active_ingredient_name
CEFAZOLIN SODIUM
upc
0371872702713
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_9317
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_53657
owl#annotatedSource
t228423
owl#someValuesFrom
t3002031