Cefazolin
CHEBI:CHEBI_474053
Definition
A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.
Chemical Information
- Molecular Formula
- C14H14N8O4S3
- Molecular Mass
- 454.511
- Charge
- 0
- SMILES
- [C@]12(N(C(=C(CS1)CSC3=NN=C(S3)C)C(=O)O)C([C@H]2NC(=O)CN4C=NN=N4)=O)[H]
- InChI
- InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
- InChIKey
- MLYYVTUWGNIJIB-BXKDBHETSA-N
Alternative Names
- (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid
- Cefamezin
- cefazolin
- cefazolina
- cefazoline
- cefazolinum
- Cephamezine
- Cephazolidin
- Cephazolin
- Cephazoline
- CEZ
Drug Classification
-
cephalosporinView Class →
CHEBI:23066
-
beta-lactam antibiotic allergenView Class →
CHEBI:88225
-
thiadiazolesView Class →
CHEBI:38099
-
tetrazolesView Class →
CHEBI:35689
-
t227290
-
t227382
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Cefazolin
- DRON_00010000
- 2180
- core#notation
- CHEBI:474053
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- labeler_name
- General Injectables and Vaccines, Inc.
- dosage_form
- POWDER, FOR SOLUTION
- marketing_start_date
- 20090201
- application_number
- ANDA209217
- spl_id
- 77cfa8c7-af08-4ae8-80a6-1e6780a17d65
- product_ndc
- 71872-7027
- route
- PARENTERAL
- package_ndc
- 72572-056-10
- package_description
- 10 VIAL, PHARMACY BULK PACKAGE in 1 CARTON (72572-056-10) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, PHARMACY BULK PACKAGE (72572-056-01)
- rxcui
- 2630753
- manufacturer_name
- General Injectables and Vaccines, Inc.
- package_marketing_start_date
- 02-SEP-21
- unii
- P380M0454Z
- spl_set_id
- c24e604f-16ca-4945-8e9d-277cc67a8c68
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Cefazolin
- DRON_00010000
- 2180
- generic_name
- Cefazolin Sodium Sterile Bulk
- brand_name
- Cefazolin Sodium
- brand_name_base
- Cefazolin Sodium
- oboInOwl#hasAlternativeId
- CHEBI:3482
- oboInOwl#id
- CHEBI:474053
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_53657
- core#notation
- CHEBI:474053
- active_ingredient_strength
- 1 g/3mL
- pharm_class
- Cephalosporins [CS]
- active_ingredient_name
- CEFAZOLIN SODIUM
- upc
- 0371872702713
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_9317
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_53657
- owl#annotatedSource
- t228423
- owl#someValuesFrom
- t3002031