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Encainide

CHEBI:CHEBI_4788

Definition

4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market.

Chemical Information

Molecular Formula
C22H28N2O2
Molecular Mass
352.46990
Charge
0
SMILES
COc1ccc(cc1)C(=O)Nc1ccccc1CCC1CCCCN1C
InChI
InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)
InChIKey
PJWPNDMDCLXCOM-UHFFFAOYSA-N

Alternative Names

  • (+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide
  • (+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
  • 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
  • 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide
  • 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
  • encainida
  • encainide
  • Encainide
  • encainidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
42368
oboInOwl#hasDbXref
Patent:US3931195
core#notation
CHEBI:4788

Additional References

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Additional Attributes

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chebi_ontology
DRON_00010000
42368
oboInOwl#hasDbXref
Patent:US3931195
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CHEBI:239046
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CHEBI:4788
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CHEBI:4788
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38633
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http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
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https://w3id.org/def/predibionto#has_side_effect25640
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